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DNAJC6 blocking peptide

DNAJC6 Immunizing Peptide

Gene Names
DNAJC6; DJC6; PARK19
Reactivity
Human, Mouse, Rat, Dog, Cow, Pig
Synonyms
DNAJC6; DNAJC6 Immunizing Peptide; DnaJ (Hsp40) homolog; subfamily C; member 6; DJC6; KIAA0473; MGC129914; MGC129915; MGC48436; subfamily B; auxilin; DNAJC6 blocking peptide
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat, Dog, Cow, Pig
Form/Format
100ug of dried peptide
Sequence
C-SPQNRPNYNVSFSA
Sequence Length
913
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
98,649 Da
NCBI Official Full Name
putative tyrosine-protein phosphatase auxilin isoform 2
NCBI Official Synonym Full Names
DnaJ heat shock protein family (Hsp40) member C6
NCBI Official Symbol
DNAJC6
NCBI Official Synonym Symbols
DJC6; PARK19
NCBI Protein Information
putative tyrosine-protein phosphatase auxilin
UniProt Protein Name
Putative tyrosine-protein phosphatase auxilin
UniProt Gene Name
DNAJC6
UniProt Synonym Gene Names
KIAA0473
UniProt Entry Name
AUXI_HUMAN

NCBI Description

DNAJC6 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 [PubMed 11147971]).[supplied by OMIM, Mar 2008]

Uniprot Description

DNAJC6: Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Chaperone; EC 3.1.3.48; Protein phosphatase, tyrosine (non-receptor)

Chromosomal Location of Human Ortholog: 1p31.3

Cellular Component: cytosol

Molecular Function: protein tyrosine phosphatase activity; SH3 domain binding

Disease: Parkinson Disease 19, Juvenile-onset

Research Articles on DNAJC6

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Product Notes

The DNAJC6 dnajc6 (Catalog #AAA426530) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The DNAJC6 Immunizing Peptide reacts with Human, Mouse, Rat, Dog, Cow, Pig and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-SPQNRPNY NVSFSA. It is sometimes possible for the material contained within the vial of "DNAJC6, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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