COVID 19 E Coronavirus Recombinant Protein | COVID-19 recombinant protein
2019-nCoV E protein; 2019-nCoV sM protein
Applications
Immunogen, calibrator or standard.
Purity
Purity: Greater than 85% as determined by reducing SDS-PAGE.Purification: Affinity purification chromatography.
Synonyms
COVID 19 E Coronavirus; 2019-nCoV E protein; 2019-nCoV sM protein; 2019 Novel Coronavirus; Coronavirus; CoV; COVID-19 virus; HCoV-2; Human Coronavirus 2019; SARS2; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; sM; COVID-19 recombinant protein
Host
E.coli
Purity/Purification
Purity: Greater than 85% as determined by reducing SDS-PAGE.
Purification: Affinity purification chromatography.
Purification: Affinity purification chromatography.
Form/Format
Supplied as a 0.2 uM filtered solution of 20mM Tris–HCl, 200mM NaCl, pH 8.0
Applicable Applications for COVID-19 recombinant protein
Immunogen, calibrator or standard.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Ships on dry ice.
Short Term: -20°C
Long Term: -80°C
Short Term: -20°C
Long Term: -80°C
Related Product Information for COVID-19 recombinant protein
Description: Recombinant 2019-nCoV Envelope Protein is produced by our E.coli expression system and the target gene encoding Met1-Val75 is expressed with a BBP, 6His tag at the N-terminus.
Background: Coronavirus envelope (E) proteins are short (100 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.
Background: Coronavirus envelope (E) proteins are short (100 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.
Product Categories/Family for COVID-19 recombinant protein
NCBI and Uniprot Product Information
Molecular Weight
Mol Mass: 27.5kDa
AP Mol Mass: 22-25kDa, reducing conditions
AP Mol Mass: 22-25kDa, reducing conditions
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Product Notes
The COVID-19 (Catalog #AAA8574736) is a Recombinant Protein produced from E.coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's COVID 19 E Coronavirus can be used in a range of immunoassay formats including, but not limited to, Immunogen, calibrator or standard. Researchers should empirically determine the suitability of the COVID-19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COVID 19 E Coronavirus, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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