Typical Testing Data/Standard Curve (for reference only)
Mouse Atrial natriuretic peptide-converting enzyme ELISA Kit | Corin elisa kit
Mouse Atrial natriuretic peptide-converting enzyme ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
CORIN: Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. Defects in CORIN are the cause of pre-eclampsia/eclampsia 5 (PEE5); also known as gestational proteinuric hypertension. Preeclampsia is a pregnancy-associated disease with maternal symptoms but placental origin. Unlike most other human disorders, it impacts 2 individuals, the mother and her child, both of whom can be severely affected. Belongs to the peptidase S1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.21.-; Membrane protein, integral; Cell surface; Protease
Cellular Component: cell surface; cytoplasmic membrane-bound vesicle; extracellular region; integral to membrane; integral to plasma membrane; membrane; plasma membrane
Molecular Function: hydrolase activity; peptidase activity; scavenger receptor activity; serine-type endopeptidase activity; serine-type peptidase activity
Biological Process: female pregnancy; neuron differentiation; peptide hormone processing; protein processing; proteolysis; regulation of blood pressure; regulation of systemic arterial blood pressure by atrial natriuretic peptide
Research Articles on Corin
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Product Notes
The Mouse Corin corin (Catalog #AAA2883144) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2883144 ELISA Kit recognizes Mouse Corin. It is sometimes possible for the material contained within the vial of "Atrial natriuretic peptide-converting enzyme, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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