COQ7 recombinant protein
Recombinant Human COQ7 Protein
Gene Names
COQ7; CAT5; CLK1; CLK-1; COQ10D8
Reactivity
Human
Applications
ELISA, Western Blot, SDS-Page
Purity
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Synonyms
COQ7; Recombinant Human COQ7 Protein; Ubiquinone biosynthesis protein COQ7 homolog; Coenzyme Q biosynthesis protein 7 homolog; Timing protein clk-1 homolog; COQ7 recombinant protein
Host
Human cells
Reactivity
Human
Purity/Purification
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 muM filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Sequence
SGMTLDNISR AAVDRIIRVD HAGEYGANRI YAGQMAVLGR TSVGPVIQKM WDQEKDHLKK FNELMVTFRV RPTVLMPLWN VLGFALGAGT ALLGKEGAMA CTVAVEESIA HHYNNQIRTL MEEDPEKYEE LLQLIKKFRD EELEHHDIGL DHDAELAPAY AVLKSIIQAG CRVAIYLSER LVDHHHHHH
Sequence Length
179
Applicable Applications for COQ7 recombinant protein
ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS)
Endotoxin
Less than 0.1 ng/mug (1 IEU/mug) as determined by LAL test.
Directions for Use
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 mug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Preparation and Storage
Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.
Related Product Information for COQ7 recombinant protein
Recombinant Human COQ7 Protein is produced by our Mammalian expression system and the target gene encoding Ser37-Leu217 is expressed with a 6His tag at the C-terminus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
20,158 Da
NCBI Official Full Name
5-demethoxyubiquinone hydroxylase, mitochondrial isoform 2
NCBI Official Synonym Full Names
coenzyme Q7, hydroxylase
NCBI Official Symbol
COQ7
NCBI Official Synonym Symbols
CAT5; CLK1; CLK-1; COQ10D8
NCBI Protein Information
5-demethoxyubiquinone hydroxylase, mitochondrial
UniProt Protein Name
5-demethoxyubiquinone hydroxylase, mitochondrial
Protein Family
UniProt Gene Name
COQ7
UniProt Synonym Gene Names
DMQ hydroxylase
UniProt Entry Name
COQ7_HUMAN
NCBI Description
The protein encoded by this gene is similar to a mitochondrial di-iron containing hydroxylase in Saccharomyces cerevisiae that is involved with ubiquinone biosynthesis. Mutations in the yeast gene lead to slower development and longer life span. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]
Uniprot Description
COQ7: Involved in lifespan determination in ubiquinone- independent manner. Involved in ubiquinone biosynthesis. Potential central metabolic regulator. Belongs to the COQ7 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cofactor and Vitamin Metabolism - ubiquinone and other terpenoid-quinone biosynthesis; Mitochondrial
Chromosomal Location of Human Ortholog: 16p12.3
Cellular Component: nucleus
Molecular Function: protein binding
Disease: Coenzyme Q10 Deficiency, Primary, 8
Research Articles on COQ7
Similar Products
Product Notes
The COQ7 coq7 (Catalog #AAA8248816) is a Recombinant Protein produced from Human cells and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Human COQ7 Protein reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's COQ7 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS). Researchers should empirically determine the suitability of the COQ7 coq7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: SGMTLDNISR AAVDRIIRVD HAGEYGANRI YAGQMAVLGR TSVGPVIQKM WDQEKDHLKK FNELMVTFRV RPTVLMPLWN VLGFALGAGT ALLGKEGAMA CTVAVEESIA HHYNNQIRTL MEEDPEKYEE LLQLIKKFRD EELEHHDIGL DHDAELAPAY AVLKSIIQAG CRVAIYLSER LVDHHHHHH. It is sometimes possible for the material contained within the vial of "COQ7, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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