COLEC10 recombinant protein

COLEC10 Protein, Mouse, Recombinant (hFc Tag)

Cat. Num. AAA8122599

• Gene Names: Colec10; CL-L1
• Purity: >85% as determined by SDS-PAGE
• Synonyms: COLEC10; COLEC10 Protein; Mouse; Recombinant (hFc Tag); Mouse COLEC10 Protein (Fc Tag); CL-L1 Protein; collectin sub-family member 10 (C-type lectin); COLEC10 recombinant protein

• Host: HEK293 Cells
• Purity/Purification: >85% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Cys119-Lys277

• Species: Mouse
• Endotoxin: <1.0EU per ug of the protein as determined by the LAL method
• Predicted N Terminal: Glu
• Tag: N-human IgG1-Fc
• Protein Construction: A DNA sequence encoding the mouse COLEC10 (Q8CF98)(Cys119-Lys277) was expressed with the Fc region of human IgG1 at the N-terminus.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

SDS-Page

Related Product Information for COLEC10 recombinant protein

Background: COLEC1 is a member of the C-lectin family. Members of this family possess collagen-like sequences and carbohydrate recognition domains. The other members of this family are secreted proteins and bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. This gene product is a cytosolic protein, a characteristic that suggests that it may have different biological functions than other C-lectins.

References

Ohtani K., et al.,(1999), Molecular cloning of a novel human collectin from liver (CL-L1). J. Biol. Chem. 274:13681-13689.Clark H.F., et al., (2003), The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.Genome Res. 13:2265-2270.Ota T., et al.,(2004), Complete sequencing and characterization of 21,243 full-length human cDNAs.Nat. Genet. 36:40-45.

NCBI and Uniprot Product Information

• NCBI GI #: 226053018
• NCBI GeneID: 239447
• NCBI Accession #: NP_775598.2
• NCBI GenBank Nucleotide #: NM_173422.3
• UniProt Accession #: Q8CF98; Q8C1C5
• Molecular Weight: 30,524 Da
• NCBI Official Full Name: collectin-10
• NCBI Official Synonym Full Names: collectin sub-family member 10
• NCBI Official Symbol: Colec10
• NCBI Official Synonym Symbols: CL-L1
• NCBI Protein Information: collectin-10
• UniProt Protein Name: Collectin-10
• Protein Family: Collectin
• UniProt Gene Name: Colec10
• UniProt Synonym Gene Names: Cll1; CL-L1
• UniProt Entry Name: COL10_MOUSE

Uniprot Description

COLEC10: Lectin that binds to various sugars: galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine. Belongs to the COLEC10/COLEC11 family.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: collagen; cytoplasm; extracellular region; nucleus; cytosol

Molecular Function: mannose binding; carbohydrate binding

Biological Process: heterophilic cell adhesion; embryonic development; defense response