Collagen type IV alpha-3-binding protein (COL4A3BP) Recombinant Protein | COL4A3BP recombinant protein

Recombinant Human Collagen type IV alpha-3-binding protein (COL4A3BP)

Cat. Num. AAA1381511

• Gene Names: COL4A3BP; CERT; GPBP; CERTL; MRD34; STARD11
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Collagen type IV alpha-3-binding protein (COL4A3BP); Recombinant Human Collagen type IV alpha-3-binding protein (COL4A3BP); COL4A3BP recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-624, Full length protein
• Sequence: MSDNQSWNSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETEYGCRGSICLSKAVITPHDFDECRFDISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYSATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQKYFDACADAVSKDELQRDKVVEDDEDDFPTTRSDGDFLHSTNGNKEKLFPHVTPKGINGIDFKGEAITFKATTAGILATLSHCIELMVKREDSWQKRLDKETEKKRRTEEAYKNAMTELKKKSHFGGPDYEEGPNSLINEEEFFDAVEAALDRQDKIEEQSQSEKVRLHWPTSLPSGDAFSSVGTHRFVQKPYSRSSSMSSIDLVSASDDVHRFSSQVEEMVQNHMTYSLQDVGGDANWQLVVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHVVETLADNAIIIYQTHKRVWPASQRDVLYLSVIRKIPALTENDPETWIVCNFSVDHDSAPLNNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANVNPGGWAPASVLRAVAKREYPKFLKRFTSYVQEKTAGKPILF
• Sequence Length: 624

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for COL4A3BP recombinant protein

This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene.

NCBI and Uniprot Product Information

• NCBI GI #: 194294543
• NCBI GeneID: 10087
• NCBI Accession #: NP_001123577.1
• NCBI GenBank Nucleotide #: NM_001130105.1
• UniProt Accession #: Q9Y5P4; Q53YV1; Q53YV2; Q96Q85; Q96Q88; Q9H2S7; Q9H2S8; A8K7S2; B3KUB7
• Molecular Weight: 83,708 Da
• NCBI Official Full Name: collagen type IV alpha-3-binding protein isoform 3
• NCBI Official Synonym Full Names: collagen type IV alpha 3 binding protein
• NCBI Official Symbol: COL4A3BP
• NCBI Official Synonym Symbols: CERT; GPBP; CERTL; MRD34; STARD11
• NCBI Protein Information: collagen type IV alpha-3-binding protein
• UniProt Protein Name: Collagen type IV alpha-3-binding protein
• Protein Family: Collagen type IV alpha-3-binding protein
• UniProt Gene Name: COL4A3BP
• UniProt Synonym Gene Names: CERT; STARD11; hCERT; GPBP; StARD11

NCBI Description

This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.