Human Collagen alpha-1(XXVII) chain ELISA Kit | COL27A1 elisa kit
Human Collagen alpha-1(XXVII) chain ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the fibrillar collagen family, and plays a role during the calcification of cartilage and the transition of cartilage to bone. The encoded protein product is a preproprotein. It includes an N-terminal signal peptide, which is followed by an N-terminal propetide, mature peptide and a C-terminal propeptide. The N-terminal propeptide contains thrombospondin N-terminal-like and laminin G-like domains. The mature peptide is a major triple-helical region. The C-terminal propeptide, also known as COLFI domain, plays crucial roles in tissue growth and repair. Mutations in this gene cause Steel syndrome. Alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been determined. [provided by RefSeq, Sep 2014]
Uniprot Description
COL27A1: Plays a role during the calcification of cartilage and the transition of cartilage to bone. Belongs to the fibrillar collagen family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 9q32
Cellular Component: endoplasmic reticulum lumen; extracellular region; fibrillar collagen
Molecular Function: extracellular matrix structural constituent; metal ion binding
Biological Process: extracellular matrix organization and biogenesis
Disease: Steel Syndrome
Research Articles on COL27A1
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Product Notes
The Human COL27A1 col27a1 (Catalog #AAA2882339) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2882339 ELISA Kit recognizes Human COL27A1. It is sometimes possible for the material contained within the vial of "Collagen alpha-1(XXVII) chain, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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