COL21A1 recombinant protein
Recombinant Human COL21A1 Protein (C-His)
Gene Names
COL21A1; FP633; COLA1L
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
COL21A1; Recombinant Human COL21A1 Protein (C-His); collagen; type XXI; alpha 1; collagen alpha-1(XXI) chain; alpha 1 type XXI collagen; FP633; COLA1L; dJ708F5.1; dJ682J15.1; FLJ39125; FLJ44623; MGC26619; DKFZp564B052; COL21A1 recombinant protein
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 mum filtered solution of PBS, pH7.4.
Sequence
Glu23-Tyr957
Sequence Length
957
Species
Human
Endotoxin
< 1.0 EU per mug as determined by the LAL method.
Fusion Tag
C-His
Preparation and Storage
Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Related Product Information for COL21A1 recombinant protein
Protein Construction: Recombinant Human COL21A1 is produced by our mammalian expression system and the target gene encoding Glu23-Tyr957 is expressed with a 6His tag at the C-terminus.
Background: Collagen alpha-1(XXI) Chain (COL21A1) is a member of the fibril-associated collagens with interruptedhelices (FACIT) family. COL21A1 is a secreted protein and contains six collagen-like domains, oneTSP N-terminal (TSPN) domain, and one VWFA domain. COL21A1 is widely expressed in manytissues with the highest expression observed at the fetal stage. COL21A1 is stimulated byPDGF/platelet-derived growth factor. Type XXI collagen is localized to tissues containing type Icollagen; it may serve to maintain the integrity of the extracellular matrix.
Background: Collagen alpha-1(XXI) Chain (COL21A1) is a member of the fibril-associated collagens with interruptedhelices (FACIT) family. COL21A1 is a secreted protein and contains six collagen-like domains, oneTSP N-terminal (TSPN) domain, and one VWFA domain. COL21A1 is widely expressed in manytissues with the highest expression observed at the fetal stage. COL21A1 is stimulated byPDGF/platelet-derived growth factor. Type XXI collagen is localized to tissues containing type Icollagen; it may serve to maintain the integrity of the extracellular matrix.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Molecular Mass: 99.7kDa
Actual Protein Molecular Mass: 115-125 & 220kDa
Actual Protein Molecular Mass: 115-125 & 220kDa
NCBI Official Full Name
collagen alpha-1(XXI) chain isoform a
NCBI Official Synonym Full Names
collagen type XXI alpha 1 chain
NCBI Official Symbol
COL21A1
NCBI Official Synonym Symbols
FP633; COLA1L
NCBI Protein Information
collagen alpha-1(XXI) chain
UniProt Protein Name
Collagen alpha-1(XXI) chain
Protein Family
UniProt Gene Name
COL21A1
UniProt Synonym Gene Names
COL1AL; FP633
UniProt Entry Name
COLA1_HUMAN
NCBI Description
This gene encodes the alpha chain of type XXI collagen, a member of the FACIT (fibril-associated collagens with interrupted helices) collagen family. Type XXI collagen is localized to tissues containing type I collagen and maintains the integrity of the extracellular matrix. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Research Articles on COL21A1
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Product Notes
The COL21A1 col21a1 (Catalog #AAA2557321) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Glu23-Tyr9 57. It is sometimes possible for the material contained within the vial of "COL21A1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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