Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Testing Data (Peptide-+)

anti-Human, Mouse Collagen VII alpha1 Antibody | anti-CO7A1 antibody

Collagen VII alpha1 Antibody

Gene Names
COL7A1; EBD1; EBR1; EBDCT; NDNC8
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
Collagen VII alpha1; Collagen VII alpha1 Antibody; Collagen alpha-1(VII) chain; Long-chain collagen; LC collagen; anti-CO7A1 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse
Specificity
Collagen VII alpha1 antibody detects endogenous levels of total Collagen VII alpha1 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
2944
Applicable Applications for anti-CO7A1 antibody
Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes
IHC: 1:50-1:100
IF: 1:100-1:500
ELISA: 1:1000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human Collagen VII alpha1.
Preparation and Storage
Store at-20 degree C for 1 year.

Testing Data

(Peptide-+)

Testing Data (Peptide-+)

Immunohistochemistry (IHC)

(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using Collagen VII alpha1 antibody. Immunofluorescence analysis of COS-7 cells, using Collagen VII alpha1 antibody.)

Immunohistochemistry (IHC) (Peptide-+ Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using Collagen VII alpha1 antibody. Immunofluorescence analysis of COS-7 cells, using Collagen VII alpha1 antibody.)
References
Christiano A.M., Genomics 21:169-179(1994). Tanaka T., Biochem. Biophys. Res. Commun. 183:958-963(1992). Gammon W.R., J. Invest. Dermatol. 99:691-696(1992).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
292,267 Da
NCBI Official Full Name
collagen alpha-1(VII) chain
NCBI Official Synonym Full Names
collagen type VII alpha 1 chain
NCBI Official Symbol
COL7A1
NCBI Official Synonym Symbols
EBD1; EBR1; EBDCT; NDNC8
NCBI Protein Information
collagen alpha-1(VII) chain
UniProt Protein Name
Collagen alpha-1(VII) chain
UniProt Gene Name
COL7A1
UniProt Synonym Gene Names
LC collagen

NCBI Description

This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq, Jul 2008]

Uniprot Description

Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen.

Research Articles on CO7A1

Similar Products

Product Notes

The CO7A1 col7a1 (Catalog #AAA858748) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Collagen VII alpha1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Collagen VII alpha1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA). IHC: 1:50-1:100 IF: 1:100-1:500 ELISA: 1:1000. Researchers should empirically determine the suitability of the CO7A1 col7a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Collagen VII alpha1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.