Consortin (CNST) Recombinant Protein | CNST recombinant protein
Recombinant Human Consortin (CNST)
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
NCBI Description
Targeting of numerous transmembrane proteins to the cell surface is thought to depend on their recognition by cargo receptors that interact with the adaptor machinery for anterograde traffic at the distal end of the Golgi complex. Consortin (CNST) is an integral membrane protein that acts as a binding partner of connexins, the building blocks of gap junctions, and acts as a trans-Golgi network (TGN) receptor involved in connexin targeting to the plasma membrane and recycling from the cell surface (del Castillo et al., 2010 [PubMed 19864490]).[supplied by OMIM, Jun 2010]
Uniprot Description
CNST: Required for targeting of connexins to the plasma membrane. Belongs to the CNST family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 1q44
Cellular Component: integral to membrane; membrane; plasma membrane; protein complex; trans-Golgi network; transport vesicle
Molecular Function: phosphatase binding; protein binding
Biological Process: positive regulation of Golgi to plasma membrane protein transport
Research Articles on CNST
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Product Notes
The CNST cnst (Catalog #AAA7011925) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-725aa; full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the CNST cnst for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MDDSDTPTYY LQIEPQDGCH PGDSVERSVT CLPSASDENE NQLDGDGHEH LTSSDSAMGK PQVSEQDSLN NNESCTLSCE VAAGENLQNT LCEASRDEQA FLGKDKKIPG KRSPRSKKGT AKKIPPGLFS GDIAPLMQEK VLSAVTYAVD DEEAAEVNAN EQPEAPKLVL QSLFSLIRGE VEQLDSRALP LCLHQIAESY FQEEDYEKAM KFIQLERLYH EQLLANLSAI QEQWETKWKT VQPHTVTALR NSEKGFNGED FERLTKICAT HQDPLLSKHK IAAVEKSQER KCSTQLLVSE DPKEGGATTK ESESKTCLGT ESSKESQHTV EPLGSSPCCH QMDVQTDSPS LSVTAGKDHM EELLCSAEAT LALHTQSSET AGSPSGPDSS EDACEDDSRL QLAQTEACQD VARIEGIAED PKVFLSSKSK TEPLISPGCD RIPPALISEG KYSQAQRKEL RLPLRDASEA LPTDQLENNE LNELQQPDLT DSDGKSPQAQ ADSDGSENVL CGNNQISDLG ILLPEVCMAP EEKGDKDDQL NKETEDYLNS LLEGCLKDTE DSLSYEDNQD DDSDLLQDLS PEEASYSLQE NLPSDESCLS LDDLAKRIEI AEVVPTEGLV SILKKRNDTV GDHPAQMQHK PSKRRVRFQE IDDSLDQDEV GGGSCILLVL LCIATVFLSV GGTALYCTFG DMESPVCTDF ADNMDFYYTK LLQGVAELKH WIYLS. It is sometimes possible for the material contained within the vial of "Consortin (CNST), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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