Canopy homolog 2 Recombinant Protein | CNPY2 recombinant protein

Recombinant Human Protein canopy homolog 2

Cat. Num. AAA717403

• Gene Names: CNPY2; MSAP; TMEM4; ZSIG9; HP10390
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Canopy homolog 2; Recombinant Human Protein canopy homolog 2; MIR-interacting saposin-like protein; Putative secreted protein Zsig9; Transmembrane protein 4; CNPY2 recombinant protein

• Host: E Coli
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Liquid containing glycerol
• Sequence Positions: 22-182aa; Full Length
• Sequence: RSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL
• Sequence Length: 84

• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

Related Product Information for CNPY2 recombinant protein

Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation.

Product Categories/Family for CNPY2 recombinant protein

Metabolism

References

Selection of cDNAs encoding putative type II membrane proteins on the cell surface from a human full-length cDNA bank.Yokoyama-Kobayashi M., Yamaguchi T., Sekine S., Kato S.Gene 228:161-167(1999) MSAP is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain.Bornhauser B.C., Olsson P.-A., Lindholm D.J. Biol. Chem. 278:35412-35420(2003) Homo sapiens putative secreted protein.Sheppard P., Jelinek L., Whitmore T., Blumberg H., Lehner J., O'Hara P.The secreted protein discovery initiative (SPDI) , a large-scale effort to identify novel human secreted and transmembrane proteins a bioinformatics assessment.Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J., Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P., Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E., Heldens S., Huang A., Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D., Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L., Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C., Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J., Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M.Genome Res. 13:2265-2270(2003) Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.Nat. Genet. 36:40-45(2004)

NCBI and Uniprot Product Information

• NCBI GI #: 300360487
• NCBI GeneID: 10330
• NCBI Accession #: NP_001177920.1
• NCBI GenBank Nucleotide #: NM_001190991.1
• UniProt Accession #: Q9Y2B0; Q9UHE9; B2R7B9
• Molecular Weight: 45.4 kDa
• NCBI Official Full Name: protein canopy homolog 2 isoform 2
• NCBI Official Synonym Full Names: canopy FGF signaling regulator 2
• NCBI Official Symbol: CNPY2
• NCBI Official Synonym Symbols: MSAP; TMEM4; ZSIG9; HP10390
• NCBI Protein Information: protein canopy homolog 2
• UniProt Protein Name: Protein canopy homolog 2
• Protein Family: Protein canopy
• UniProt Gene Name: CNPY2
• UniProt Synonym Gene Names: MSAP; TMEM4; ZSIG9
• UniProt Entry Name: CNPY2_HUMAN

Uniprot Description

TMEM4: Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation. Belongs to the canopy family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Membrane protein, integral; Endoplasmic reticulum; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 12q15

Cellular Component: endoplasmic reticulum; integral to plasma membrane

Molecular Function: protein binding

Biological Process: positive regulation of low-density lipoprotein receptor biosynthetic process