Protein cornichon (cni) Recombinant Protein | cni recombinant protein
Recombinant Drosophila melanogaster Protein cornichon (cni)
NCBI and Uniprot Product Information
Uniprot Description
Function: Acts as cargo receptor necessary for the transportation of gurken (grk) to a transitional endoplasmic reticulum (tER) site and promotes its incorporation into coat protein complex II (COPII) vesicles. Associated with gurken, produces a signal received by torpedo resulting in a signaling pathway that first establishes posterior follicle cell fates and normal localization of the anterior and posterior determinants, later they act in a signaling event inducing dorsal follicle cell fates and regulating the dorsal-ventral pattern of egg and embryo. Ref.1 Ref.6
Subunit structure: Interacts with grk. Ref.6
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein Ref.6.
Tissue specificity: Expressed in male and female somatic tissues. Ref.6
Developmental stage: Detectable in the germline from germarium stages onwards and becomes enriched within the oocyte during early and middle stages of oogenesis. In early stages, it is present in the nurse cell oocyte cluster. It is highly expressed in stage 1-6 egg chambers, expression ceases during stage 7 and cannot be detected in stages 8 and 9. During stage 10, it is reexpressed in the nurse cells. Ref.1 Ref.6
Sequence similarities: Belongs to the cornichon family.
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Product Notes
The cni cni (Catalog #AAA1000157) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-144. The amino acid sequence is listed below: MAFNFTAFTY IVALIGDAFL IFFAIFHVIA FDELKTDYKN PIDQCNSLNP LVLPEYLLHI FLNLLFLFCG EWFSLCINIP LIAYHIWRYK NRPVMSGPGL YDPTTVLKTD TLYRNMREGW IKLAVYLISF FYYIYGMVYS LIST. It is sometimes possible for the material contained within the vial of "Protein cornichon (cni), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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