CMV recombinant protein
Purified Recombinant CMV protein (gH pentamer complex) (His tag)
Purity
> 95% by SDS-PAGE
Synonyms
CMV; Purified Recombinant CMV protein (gH pentamer complex) (His tag); CMV antigen; Cytomegalovirus antigen; Cytomegalovirus protein.; CMV recombinant protein
Host
VR1814
Purity/Purification
> 95% by SDS-PAGE
Form/Format
0.2um filtered liquid in Dulbecco's PBS.
Concentration
1.0mg/ml (varies by lot)
Sequence Length
218
Grade
Recombinant
Expression system
HEK293
Species
Viral
Protein type
Recombinant
Biohazard
Recombinant protein with His tag. Use standard laboratory precautions when handling this material.
Tag/Conjugate
His tag
Biological Significance
The Cytomegalovirus gH Pentamer Complex is expressed on all wildtype hCMV strains but is notably missing from laboratory strains suchs as AD169. Receptor-mediated viral entry into endothelial cells requires a functional gH pentamric complex, ant his complex is one of the primary targets for antiviral antibodies in infected individuals.
Implications in Disease
Most people infected with CMV who are otherwise healthy experience few if any symptoms. When first infected, some adults may have symptoms similar to mononucleosis, including fatigue, fever and muscle aches. An illness resemling infectious mononucleosis is the most common presentation of CMV in people with weakened immune systems (immunocompromised).CMV also can attack specific organs . Signs and symptoms may include: Fever, Pneumonia, Diarrhea, Ulcers in the digestive tract, Hepatitis, Inflammation of the brain ( encephalitis,) Behavorial changes ,Seizures, Coma, Visual impairment and blindness, Newbors infected with CMV in the womb (congenital CMV), babies who become infeted during birth or shortly after birth (perinatal CMV) such as through breast-feeding and people with weakened immune systems are more at risk of developing signs and symptoms than are healthy adults.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Ships on dry ice. Upon receipt store at -80°C . Avoid repeat freeze/thaw cycles.
Product Categories/Family for CMV recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
CMV coat protein
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Product Notes
The CMV (Catalog #AAA5308580) is a Recombinant Protein produced from VR1814 and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CMV, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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