UMP-CMP kinase 2, mitochondrial (CMPK2) Recombinant Protein | CMPK2 recombinant protein
Recombinant Human UMP-CMP kinase 2, mitochondrial (CMPK2)
Gene Names
CMPK2; NDK; TYKi; TMPK2; UMP-CMPK2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
UMP-CMP kinase 2; mitochondrial (CMPK2); Recombinant Human UMP-CMP kinase 2; CMPK2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
99-449, Full length protein
Sequence
LHQLRRGPFQRCQLLRLLCYCPGGQAGGAQQGFLLRDPLDDPDTRQALLELLGACQEAPRPHLGEFEADPRGQLWQRLWEVQDGRRLQVGCAQVVPVPEPPLHPVVPDLPSSVVFPDREAARAVLEECTSFIPEARAVLDLVDQCPKQIQKGKFQVVAIEGLDATGKTTVTQSVADSLKAVLLKSPPSCIGQWRKIFDDEPTIIRRAFYSLGNYIVASEIAKESAKSPVIVDRYWHSTATYAIATEVSGGLQHLPPAHHPVYQWPEDLLKPDLILLLTVSPEERLQRLQGRGMEKTREEAELEANSVFRQKVEMSYQRMENPGCHVVDASPSREKVLQTVLSLIQNSFSEP
Sequence Length
351
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
44,959 Da
NCBI Official Full Name
UMP-CMP kinase 2, mitochondrial isoform 2
NCBI Official Synonym Full Names
cytidine/uridine monophosphate kinase 2
NCBI Official Symbol
CMPK2
NCBI Official Synonym Symbols
NDK; TYKi; TMPK2; UMP-CMPK2
NCBI Protein Information
UMP-CMP kinase 2, mitochondrial
UniProt Protein Name
UMP-CMP kinase 2, mitochondrial
UniProt Gene Name
CMPK2
NCBI Description
This gene encodes one of the enzymes in the nucleotide synthesis salvage pathway that may participate in terminal differentiation of monocytic cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
Uniprot Description
May participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor. Efficacy is highest for dUMP followed by dCMP; CMP and UMP are poor substrates. May be involved in mtDNA depletion caused by long term treatment with ddC or other pyrimidine analogs. Also displays broad nucleoside diphosphate kinase activity.
Research Articles on CMPK2
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Product Notes
The CMPK2 cmpk2 (Catalog #AAA1280956) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 99-449, Full length protein. The amino acid sequence is listed below: LHQLRRGPFQ RCQLLRLLCY CPGGQAGGAQ QGFLLRDPLD DPDTRQALLE LLGACQEAPR PHLGEFEADP RGQLWQRLWE VQDGRRLQVG CAQVVPVPEP PLHPVVPDLP SSVVFPDREA ARAVLEECTS FIPEARAVLD LVDQCPKQIQ KGKFQVVAIE GLDATGKTTV TQSVADSLKA VLLKSPPSCI GQWRKIFDDE PTIIRRAFYS LGNYIVASEI AKESAKSPVI VDRYWHSTAT YAIATEVSGG LQHLPPAHHP VYQWPEDLLK PDLILLLTVS PEERLQRLQG RGMEKTREEA ELEANSVFRQ KVEMSYQRME NPGCHVVDAS PSREKVLQTV LSLIQNSFSE P. It is sometimes possible for the material contained within the vial of "UMP-CMP kinase 2, mitochondrial (CMPK2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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