Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Chemokine-like receptor 1 (Cmklr1) Recombinant Protein | Cmklr1 recombinant protein

Recombinant Rat Chemokine-like receptor 1 (Cmklr1)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Chemokine-like receptor 1 (Cmklr1); Recombinant Rat Chemokine-like receptor 1 (Cmklr1); Recombinant Chemokine-like receptor 1 (Cmklr1); Chemokine-like receptor 1; G-protein coupled chemoattractant-like receptor G-protein coupled receptor DEZ; Cmklr1 recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-371
Sequence
MEYEGYNDSSIYGEEYSDGSDYIVDLEEAGPLEAKVAEVFLVVIYSLVCFLGILGNGLVIVIATFKMKKTVNTVWFVNLAVADFLFNIFLPIHITYAAMDYHWVFGKAMCKISSFLLSHNMYTSVFLLTVISFDRCISVLLPVWSQNHRSVRLAYMTCVVVWVWLSSESPPSLVFGHVSTSHGKITCFNNFSLAAPEPFSHSTHPRTDPVGYSRHVAVTVTRFLCGFLIPVFIITACYLTIVFKLQRNRQAKTKKPFKIIITIIITFFLCWCPYHTLYLLELHHTAVPASVFSLGLPLATAVAIANSCMNPILYVFMGHDFKKFKVALFSRLVNALSEDTGPSSYPSHRSFTKMSSLIEKASVNEKETSTL
Sequence Length
371
Species
Rattus norvegicus (Rat)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
41,723 Da
NCBI Official Full Name
Chemokine-like receptor 1
NCBI Official Synonym Full Names
chemokine-like receptor 1
NCBI Official Symbol
Cmklr1
NCBI Protein Information
chemokine-like receptor 1; chemokine receptor-like 1; G-protein coupled receptor DEZ; G-protein coupled chemoattractant-like receptor
UniProt Protein Name
Chemokine-like receptor 1
UniProt Gene Name
Cmklr1
UniProt Synonym Gene Names
Dez
UniProt Entry Name
CML1_RAT

NCBI Description

may be a member of the chemokine receptor family [RGD, Feb 2006]

Uniprot Description

CMKLR1: Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF- kappa-B. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2). Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein chemoattractant receptor activity; chemokine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of interleukin-12 production; inhibition of NF-kappaB transcription factor; positive regulation of fat cell differentiation; regulation of calcium-mediated signaling; chemotaxis

Research Articles on Cmklr1

Similar Products

Product Notes

The Cmklr1 cmklr1 (Catalog #AAA1152874) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-371. The amino acid sequence is listed below: MEYEGYNDSS IYGEEYSDGS DYIVDLEEAG PLEAKVAEVF LVVIYSLVCF LGILGNGLVI VIATFKMKKT VNTVWFVNLA VADFLFNIFL PIHITYAAMD YHWVFGKAMC KISSFLLSHN MYTSVFLLTV ISFDRCISVL LPVWSQNHRS VRLAYMTCVV VWVWLSSESP PSLVFGHVST SHGKITCFNN FSLAAPEPFS HSTHPRTDPV GYSRHVAVTV TRFLCGFLIP VFIITACYLT IVFKLQRNRQ AKTKKPFKII ITIIITFFLC WCPYHTLYLL ELHHTAVPAS VFSLGLPLAT AVAIANSCMN PILYVFMGHD FKKFKVALFS RLVNALSEDT GPSSYPSHRS FTKMSSLIEK ASVNEKETST L. It is sometimes possible for the material contained within the vial of "Chemokine-like receptor 1 (Cmklr1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.