IK Cytokine, Down Regulator Of HLA II (IK) CLIA Kit | IK clia kit

CLIA Kit for IK Cytokine, Down Regulator Of HLA II (IK)

Cat. Num. AAA2000959

• Gene Names: IK; RED; CSA2
• Synonyms: IK Cytokine; Down Regulator Of HLA II (IK); CLIA Kit for IK Cytokine; IK clia kit

• Specificity: This assay has high sensitivity and excellent specificity for detection of IK Cytokine, Down Regulator Of HLA II (IK); No significant cross-reactivity or interference between IK Cytokine, Down Regulator Of HLA II (IK) and analogues was observed.
• Sequence Length: 557

• Assay Type: Sandwich
• Samples: Tissue homogenates and other biological fluids
• Detection Range: 0.014-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 3.33ng/mL, 1.11ng/mL, 0.37ng/mL, 0.123ng/mL, 0.041ng/mL, 0.014ng/mL
• Sensitivity: The minimum detectable dose of this kit is typically less than 0.066ng/mL
• Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level IK Cytokine, Down Regulator Of HLA II (IK) were tested 20 times on one plate, respectively.; Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level IK Cytokine, Down Regulator Of HLA II (IK) were tested on 3 different plates, 8 replicates in each plate.; CV(%) = SD/meanX100; Intra-Assay: CV<10%; Inter-Assay: CV<12%
• Organism Species: Rattus norvegicus (Rat)
• Assay Length: 4.5 hours
• Preparation and Storage: The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.; To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for IK clia kit

The microtiter plate provided in this kit has been pre-coated with an antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated secondary antibody. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then the mixture of substrate A and B is added to generate glow light emission kinetics. Upon plate development, the intensity of the emitted light is proportional to the IK Cytokine, Down Regulator Of HLA II (IK) level in the sample or standard.

NCBI and Uniprot Product Information

• NCBI GI #: 47940619
• NCBI GeneID: 3550
• UniProt Accession #: Q13123; Q6IPD8
• Molecular Weight: 65,602 Da
• NCBI Official Full Name: IK cytokine, down-regulator of HLA II
• NCBI Official Synonym Full Names: IK cytokine, down-regulator of HLA II
• NCBI Official Symbol: IK
• NCBI Official Synonym Symbols: RED; CSA2
• NCBI Protein Information: protein Red; IK factor; RD element; cytokine IK; prer protein; chondrosarcoma-associated protein 2
• UniProt Protein Name: Protein Red
• Protein Family: Protein
• UniProt Gene Name: IK
• UniProt Synonym Gene Names: RED; RER
• UniProt Entry Name: RED_HUMAN

NCBI Description

The protein encoded by this gene was identified by its RED repeat, a stretch of repeated arginine, glutamic acid and aspartic acid residues. The protein localizes to discrete dots within the nucleus, excluding the nucleolus. Its function is unknown. This gene maps to chromosome 5; however, a pseudogene may exist on chromosome 2. [provided by RefSeq, Jul 2008]

Uniprot Description

IK: May bind to chromatin. Belongs to the RED family.

Protein type: Cytokine; Spliceosome

Chromosomal Location of Human Ortholog: 5q31.3

Cellular Component: nucleoplasm; extracellular space; nucleolus

Molecular Function: identical protein binding; protein binding

Biological Process: cell-cell signaling; immune response