CLEC2D recombinant protein

Human CLEC2D Protein, His Tag

Cat. Num. AAA188768

• Gene Names: CLEC2D; CLAX; LLT1; OCIL
• Purity: >90%; affinity purification
• Synonyms: CLEC2D; Human CLEC2D Protein; His Tag; CLAX; LLT1; OCIL; CLEC2D recombinant protein

• Host: HEK293 cells
• Purity/Purification: >90%; affinity purification
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose is added as protectants before lyophilization.
• Sequence: 6×His+CLEC2D (Arg60-Val191)

• Species: Human
• Tag: N-6×His tag
• Reconstitution: Reconstitute with deionized water
• Preparation and Storage: Store at -80 degree C for 12 months (Avoid repeated freezing and thawing)

SDS-Page

(Figure 1. Human CLEC2D Protein, His Tag on SDS-PAGE under reducing condition.)

Related Product Information for CLEC2D recombinant protein

This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Oct 2010]

NCBI and Uniprot Product Information

• NCBI GI #: 7019447
• NCBI GeneID: 29121
• NCBI Accession #: NP_037401
• NCBI GenBank Nucleotide #: NM_013269.5
• UniProt Accession #: Q9UHP7; Q6YID5; Q8WUP7; Q9HD37; Q9HD38; D6CI39; D6CI40; D6CI41
• Molecular Weight: 17.7 kDa (155aa)
• NCBI Official Full Name: C-type lectin domain family 2 member D isoform 1
• NCBI Official Synonym Full Names: C-type lectin domain family 2 member D
• NCBI Official Symbol: CLEC2D
• NCBI Official Synonym Symbols: CLAX; LLT1; OCIL
• NCBI Protein Information: C-type lectin domain family 2 member D
• UniProt Protein Name: C-type lectin domain family 2 member D
• Protein Family: C-type lectin domain family
• UniProt Gene Name: CLEC2D
• UniProt Synonym Gene Names: CLAX; LLT1; OCIL; LLT-1

NCBI Description

This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Oct 2010]

Uniprot Description

Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis (PubMed:20843815, PubMed:16339513). Inhibits osteoclast formation (PubMed:14753741, PubMed:15123656). Inhibits bone resorption (PubMed:14753741). Modulates the release of interferon-gamma (PubMed:15104121). Binds high molecular weight sulfated glycosaminoglycans (PubMed:15123656).