CIRBP recombinant protein
Recombinant Human CIRBP
Gene Names
CIRBP; CIRP
Applications
Western Blot, ELISA
Purity
Greater than 95% by SDS-PAGE gel analyses
Synonyms
CIRBP; Recombinant Human CIRBP; A18 hnRNP; A18HNRNP; cirbp; CIRBP_HUMAN; CIRP; Cold inducible RNA binding protein; Cold-inducible RNA-binding protein; Glycine rich RNA binding protein; Glycine-rich RNA-binding protein CIRP; testicular tissue protein Li 39; CIRBP recombinant protein
Host
E Coli
Purity/Purification
Greater than 95% by SDS-PAGE gel analyses
Form/Format
Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose, pH7.4
Sequence Positions
1-172
Applicable Applications for CIRBP recombinant protein
Western Blot (WB), ELISA (EIA)
Species
Human
Tag
N-terminal His-IF2DI Tag
Reconstitution
Centrifuge the vial at 10,000rpm for 1 minute, reconstitute at 200ug/ml in sterile distilled water
Preparation and Storage
Store at -20 degree C for 12 months as lyophilized; 2-8 degree C for 1 month under sterile conditions after reconstitution
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
172
NCBI Official Full Name
Cold-inducible RNA-binding protein
NCBI Official Synonym Full Names
cold inducible RNA binding protein
NCBI Official Symbol
CIRBP
NCBI Official Synonym Symbols
CIRP
NCBI Protein Information
cold-inducible RNA-binding protein; A18 hnRNP; glycine-rich RNA binding protein; cold inducible RNA-binding protein
UniProt Protein Name
Cold-inducible RNA-binding protein
Protein Family
UniProt Gene Name
CIRBP
UniProt Synonym Gene Names
A18HNRNP; CIRP
UniProt Entry Name
CIRBP_HUMAN
Uniprot Description
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (). Promotes assembly of stress granules (SGs), when overexpressed.
Research Articles on CIRBP
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Product Notes
The CIRBP cirbp (Catalog #AAA7613610) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-172. AAA Biotech's CIRBP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). Researchers should empirically determine the suitability of the CIRBP cirbp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CIRBP, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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