Rat Cold-inducible RNA-binding protein ELISA Kit | Cirbp elisa kit

Rat Cold-inducible RNA-binding protein ELISA Kit

Cat. Num. AAA2883741

• Reactivity: Rat
• Synonyms: Cold-inducible RNA-binding protein; Rat Cold-inducible RNA-binding protein ELISA Kit; A18 hnRNP; Glycine-rich RNA-binding protein CIRP; Cirbp; Cirp; Cirbp elisa kit

• Reactivity: Rat
• Sequence Length: 172

• Assay Type: Sandwich
• Detection Range: 78-5000 pg/ml
• Sensitivity: 39.3 pg/mL
• Intra-Assay CV: <=5.3%
• Inter-Assay CV: <=8.1%
• Recovery: 103%
• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 564358328
• NCBI GeneID: 81825
• NCBI Accession #: XP_006241076.1
• NCBI GenBank Nucleotide #: XM_006241014.2
• UniProt Accession #: P60825; O09069; O09148; Q61413
• Molecular Weight: 18,607 Da
• NCBI Official Full Name: cold-inducible RNA-binding protein isoform X1
• NCBI Official Synonym Full Names: cold inducible RNA binding protein
• NCBI Official Symbol: Cirbp
• NCBI Protein Information: cold-inducible RNA-binding protein
• UniProt Protein Name: Cold-inducible RNA-binding protein
• Protein Family: Cold-inducible RNA-binding protein
• UniProt Gene Name: Cirbp
• UniProt Synonym Gene Names: Cirp
• UniProt Entry Name: CIRBP_RAT

NCBI Description

expression decreased by ischemia and H2O2; may mediate generation of reactive oxygen species [RGD, Feb 2006]

Uniprot Description

Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor. Promotes assembly of stress granules (SGs), when overexpressed ().