SDS-PAGE
CIB2 / KIP-2 recombinant protein
Recombinant Human CIB2 / KIP-2 Protein (His tag)
SDS-PAGE
SDS-PAGE
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is similar to that of KIP/CIB, calcineurin B, and calmodulin. The encoded protein is a calcium-binding regulatory protein that interacts with DNA-dependent protein kinase catalytic subunits (DNA-PKcs), and it is involved in photoreceptor cell maintenance. Mutations in this gene cause deafness, autosomal recessive, 48 (DFNB48), and also Usher syndrome 1J (USH1J). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Uniprot Description
CIB2: Critical for proper photorecetor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process
Protein type: Calcium-binding
Chromosomal Location of Human Ortholog: 15q25.1
Cellular Component: cytoplasm; photoreceptor inner segment; photoreceptor outer segment; stereocilium
Molecular Function: calcium ion binding; magnesium ion binding; protein binding; protein homodimerization activity
Biological Process: calcium ion homeostasis; elevation of cytosolic calcium ion concentration; photoreceptor cell maintenance
Disease: Deafness, Autosomal Recessive 48; Usher Syndrome, Type Ij
Research Articles on CIB2 / KIP-2
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Product Notes
The CIB2 / KIP-2 cib2 (Catalog #AAA2545475) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The recombinant human CIB2 consisting of 198 amino acids and has a calculated molecular mass of 23.1 kDa. The apparent molecular mass of the protein is approximately 27 kDa in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the CIB2 / KIP-2 cib2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CIB2 / KIP-2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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