Rat Neuronal acetylcholine receptor subunit alpha-4 ELISA Kit | Chrna4 elisa kit
Rat Neuronal acetylcholine receptor subunit alpha-4 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
nicotinic acetylcholine receptor subunit responsible for binding calcium sensor protein visinin-like protein-1 (Vilip1), which modulates acetylcholine receptor expression and sensitivity [RGD, Feb 2006]
Uniprot Description
nAChRA4: a ligand-gated ion channels that binds acetylcholine and mediates fast signal transmission at synapses. After binding acetylcholine, these pentameric receptors undergo an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. An integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor.
Protein type: Channel, ligand-gated; Receptor, misc.; Membrane protein, multi-pass; Membrane protein, integral
Cellular Component: cell junction; cell soma; dendrite; external side of plasma membrane; membrane; nicotinic acetylcholine-gated receptor-channel complex; plasma membrane; postsynaptic membrane
Molecular Function: acetylcholine binding; acetylcholine receptor activity; drug binding; ion channel activity; nicotinic acetylcholine-activated cation-selective channel activity; protein binding; protein heterodimerization activity
Biological Process: B cell activation; behavioral response to nicotine; calcium ion transport; cognition; DNA repair; locomotory behavior; membrane depolarization; neurological system process; neuromuscular synaptic transmission; positive regulation of dopamine secretion; protein heterooligomerization; regulation of action potential; regulation of dopamine secretion; regulation of inhibitory postsynaptic membrane potential; regulation of membrane potential; respiratory gaseous exchange; response to hypoxia; response to nicotine; response to oxidative stress; sensory perception of pain; signal transduction; synaptic transmission, cholinergic
Research Articles on Chrna4
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Product Notes
The Rat Chrna4 chrna4 (Catalog #AAA2882464) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2882464 ELISA Kit recognizes Rat Chrna4. It is sometimes possible for the material contained within the vial of "Neuronal acetylcholine receptor subunit alpha-4, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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