CD80 IgG2a Fc & Hinge Region, Fusion Protein
CD80 IgG2a Fc & Hinge Region, Fusion Protein (B7-1 Costimulator Protein) (Biotin)
Applications
ELISA, Flow Cytometry, Functional Assay
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
CD80 IgG2a Fc & Hinge Region; Fusion Protein; Fusion Protein (B7-1 Costimulator Protein) (Biotin); Fusion Protein protein
Host
CHO cells
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in FBS, 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3.
Applicable Applications for CD80 IgG2a Fc & Hinge Region, Fusion Protein protein
ELISA (EL/EIA), Flow Cytometry (FC/FACS)
Application Notes
Suitable for use in ELISA, Flow cytometry., Recommended Dilution Optimal dilutions to be determined by the researcher.
Molecular Structure
A soluble dimeric fusion protein consisting of the extracellular (173aa) domain of human CD80 fused to murine IgG2a Fc + hinge (232 aa). Predicted monomeric molecular weight: 51.3kD.
Functional Application
CD80-muIg fusion protein blocks binding of anti-human CD80 to human tumor cells.
Human CD80-muIg/Biotin Fusion Protein*
Human CD80-muIg/Biotin Fusion Protein*
Transfectant Cell Line
CHO
Preparation and Storage
May be stored at 4 degree C. For long-term storage, aliquot and store at 4 degree C. Do not freeze. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for CD80 IgG2a Fc & Hinge Region, Fusion Protein protein
CD80, also known as BB1/B7-1, is a 60kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed on activated B cells, T cells, monocytes and dendritic cells. It is a ligand of the two T cell costimulatory molecules, CD28 and CD152 (CTLA-4). The interaction of CD80 (or CD86) with CD28 provides a costimulatory signal for T cells activated through the CD3/TCR complex.
Product Categories/Family for CD80 IgG2a Fc & Hinge Region, Fusion Protein protein
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Product Notes
The CD80 IgG2a Fc & Hinge Region, Fusion Protein (Catalog #AAA634468) is a Protein produced from CHO cells and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD80 IgG2a Fc & Hinge Region, Fusion Protein can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Flow Cytometry (FC/FACS). Suitable for use in ELISA, Flow cytometry., Recommended Dilution Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the CD80 IgG2a Fc & Hinge Region, Fusion Protein for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD80 IgG2a Fc & Hinge Region, Fusion Protein, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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