Testing Data
(EIA binding of C2380-03F to C2380-03A antibody coated plate)
CD28 IgG2a Fc, Fusion Protein
CD28 IgG2a Fc, Fusion Protein (Biotin)
Applications
ELISA
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
CD28 IgG2a Fc; Fusion Protein; Fusion Protein (Biotin); Fusion Protein protein
Host
CHO cells
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in FBS, 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3.
Applicable Applications for CD28 IgG2a Fc, Fusion Protein protein
ELISA (EL/EIA)
Application Notes
Suitable for use in ELISA and Antibody Blocking.
Molecular Structure
A soluble fusion protein consisting of the extracellular (134 aa) domain of human CD28 fused to murine IgG2a Fc (232 aa), with a predicted monomeric molecular weight of 41.8kD.
Functional Application
CD28-muIg fusion protein blocks binding of anti-human CD28 to human tumor cells.
Transfectant Cell Line
CHO
Human CD28-muIg/Biotin Fusion Protein
Human CD28-muIg/Biotin Fusion Protein
Preparation and Storage
May be stored at 4 degree C. For long-term storage, aliquot and store at 4 degree C. Do not freeze. Stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Testing Data
(EIA binding of C2380-03F to C2380-03A antibody coated plate)
Testing Data
(EIA binding of C2380-03F to C2380-03A antibody coated plate)
Related Product Information for CD28 IgG2a Fc, Fusion Protein protein
Human CD28 is an important costimulatory molecule found on all CD4+ T cells and on about half of the CD8+ T cells. T cell activities attributed to CD28 include, prevention of anergy, induction of cytokine gene transcription, stabilization of cytokine mRNAs and activation of CD8+ cytotoxic T lymphocytes. The ligands for CD28, identified as CD80 (B7-1) and CD86 (B7-2), are immunoglobulin superfamily monomeric transmembrane glycoproteins of 60kD and 80kD, respectively.
Product Categories/Family for CD28 IgG2a Fc, Fusion Protein protein
Similar Products
Product Notes
The CD28 IgG2a Fc, Fusion Protein (Catalog #AAA635150) is a Protein produced from CHO cells and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD28 IgG2a Fc, Fusion Protein can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Suitable for use in ELISA and Antibody Blocking. Researchers should empirically determine the suitability of the CD28 IgG2a Fc, Fusion Protein for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD28 IgG2a Fc, Fusion Protein, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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