Chicken SH2-containing protein (SHC / SLP-76) ELISA Kit | SHC / SLP-76 elisa kit
Chicken SH2-containing protein (SHC / SLP-76) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor-like domain which allows this signaling protein to form a complex with scaffolding protein Crk-associated substrate. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Uniprot Description
SHEP1: an adaptor protein linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated protein kinase signaling pathway. Directly links activated, tyrosine-phosphorylated Eph receptors to small Ras superfamily GTPases. Positively regulates T cell receptor-mediated interleukin-2 production by Jurkat cells.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 9q34.11
Cellular Component: membrane; cytoplasm
Molecular Function: protein binding; SH3/SH2 adaptor activity; guanyl-nucleotide exchange factor activity
Biological Process: positive regulation of signal transduction; small GTPase mediated signal transduction; JNK cascade; positive regulation of GTPase activity
Research Articles on SHC / SLP-76
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Product Notes
The Chicken SHC / SLP-76 sh2d3c (Catalog #AAA264805) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA264805 ELISA Kit recognizes Chicken SHC / SLP-76. It is sometimes possible for the material contained within the vial of "SH2-containing protein (SHC / SLP-76), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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