Chicken PAN2 poly (A) specific ribonuclease subunit homolog (S. cerevisiae) ELISA Kit | PAN2 elisa kit
Chicken PAB-dependent poly, PAN2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Function: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA when the poly(A) stretch is bound by poly(A)-binding protein (PABP), which is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1 UniRule annotationHAMAP-Rule:MF_03182
Catalytic activity: Exonucleolytic cleavage of poly(A) to 5'-AMP.UniRule annotationHAMAP-Rule:MF_03182
Enzyme regulation: Positively regulated by the regulatory subunit PAN3 UniRule annotationHAMAP-Rule:MF_03182
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Product Notes
The Chicken PAN2 pan2 (Catalog #AAA9316680) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9316680 ELISA Kit recognizes Chicken PAN2. It is sometimes possible for the material contained within the vial of "PAN2 poly (A) specific ribonuclease subunit homolog (S. cerevisiae), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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