Chicken Mediator of RNA polymerase II transcription subunit 12-like protein (MED12L) ELISA Kit | MED12L elisa kit
Chicken Mediator of RNA polymerase II transcription subunit 12-like protein (MED12L) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is part of the Mediator complex, which is involved in transcriptional coactivation of nearly all RNA polymerase II-dependent genes. The Mediator complex links gene-specific transcriptional activators with the basal transcription machinery. [provided by RefSeq, May 2010]
Uniprot Description
MED12L: May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Belongs to the Mediator complex subunit 12 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription initiation complex
Chromosomal Location of Human Ortholog: 3q25.1
Cellular Component: Srb-mediator complex
Molecular Function: beta-catenin binding; transcription factor binding
Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter
Research Articles on MED12L
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Product Notes
The Chicken MED12L med12l (Catalog #AAA7246627) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7246627 ELISA Kit recognizes Chicken MED12L. It is sometimes possible for the material contained within the vial of "Mediator of RNA polymerase II transcription subunit 12-like protein (MED12L), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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