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Cell Growth Regulator With EF-Hand Domain 1 Recombinant Protein | CGREF1 recombinant protein

Recombinant Human Cell Growth Regulator With EF-Hand Domain 1

Gene Names
CGREF1; CGR11
Purity
Greater than 85% as determined by SDS-PAGE.
Synonyms
Cell Growth Regulator With EF-Hand Domain 1; Recombinant Human Cell Growth Regulator With EF-Hand Domain 1; CGREF1 Human; Cell Growth Regulator With EF-Hand Domain 1 Human Recombinant; Cell Growth Regulatory Gene 11 Protein; Hydrophobestin; CGR11; Cell Growth Regulator With EF Hand Domain Protein 1; Cell Growth Regulator With EF Hand Domain 1; Cell growth regulator with EF hand domain protein 1; CGREF1 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 85% as determined by SDS-PAGE.
Form/Format
CGREF1 protein solution (0.5mg/ml) containing Phosphate Buffered Saline (pH7.4).
Sterile filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSAPKDGVT RPDSEVQHQL LPNPFQPGQE QLGLLQSYLK GLGRTEVQLEHLSREQVLLY LFALHDYDQS GQLDGLELLS MLTAALAPGA ANSPTTNPVI LIVDKVLETQ DLNGDGLMTPAELINFPGVA LRHVEPGEPL APSPQEPQAV GRQSLLAKSP LRQETQEAPG PREEAKGQVE ARRESLDPVQEPGGQAEADG DVPGPRGEAE GQAEAKGDAP GPRGEAGGQA EAEGDAPGPR GEAGGQAEAR ENGEEAKELPGETLESKNTQ NDFEVHIVQV ENDEI
Sequence Length
318
Related Product Information for CGREF1 recombinant protein
Introduction: Cell Growth Regulator with EF-Hand Domain 1, also known as CGREF1 is a secreted calcium ion binding protein. CGREF1 includes two EF-hand domains & both EF-hands are essential for function. CGREF1 is most likely digested extracellularly by an unfamiliar serine protease generating extremely hydrophobic bioactive peptides. CGREF1 mediates cell-cell adhesion in a calcium-dependent manner. In addition, CGREF1 is capable to inhibit growth in more than a few cell lines.

Description: CGREF1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 305 amino acids (20-301 a.a) and having a molecular mass of 32.3kDa. CGREF1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for CGREF1 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,064 Da
NCBI Official Full Name
cell growth regulator with EF hand domain protein 1 isoform a
NCBI Official Synonym Full Names
cell growth regulator with EF-hand domain 1
NCBI Official Symbol
CGREF1
NCBI Official Synonym Symbols
CGR11
NCBI Protein Information
cell growth regulator with EF hand domain protein 1
UniProt Protein Name
Cell growth regulator with EF hand domain protein 1
UniProt Gene Name
CGREF1
UniProt Synonym Gene Names
CGR11
UniProt Entry Name
CGRE1_HUMAN

Uniprot Description

CGREF1: Mediates cell-cell adhesion in a calcium-dependent manner. Able to inhibit growth in several cell lines.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 2p23.3

Biological Process: negative regulation of cell proliferation; response to stress

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Product Notes

The CGREF1 cgref1 (Catalog #AAA140596) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSAPK DGVT RPDSEVQHQL LPNPFQPGQE QLGLLQSYLK GLGRTEVQLE HLSREQVLLY LFALHDYDQS GQLDGLELLS MLTAALAPGA ANSPTTNPVI LIVDKVLETQ DLNGDGLMTP AELINFPGVA LRHVEPGEPL APSPQEPQAV GRQSLLAKSP LRQETQEAPG PREEAKGQVE ARRESLDPVQ EPGGQAEADG DVPGPRGEAE GQAEAKGDAP GPRGEAGGQA EAEGDAPGPR GEAGGQAEAR ENGEEAKELP GETLESKNTQ NDFEVHIVQV ENDEI. It is sometimes possible for the material contained within the vial of "Cell Growth Regulator With EF-Hand Domain 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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