Typical Testing Data/Standard Curve (for reference only)
Human complement factor H-related 1 ELISA Kit | CFHR1 elisa kit
Human Complement factor H-related protein 1, CFHR1 ELISA Kit
Gene Names
CFHR1; CFHL; FHR1; HFL1; HFL2; CFHL1; H36-1; H36-2; CFHL1P; CFHR1P
Reactivity
Human
Synonyms
complement factor H-related 1; Human Complement factor H-related protein 1; CFHR1 ELISA Kit; Human Complement factor H-related protein 1 (CFHR1) ELISA kit; CFHL; CFHL1; CFHL1P; CFHR1P; FHR1; H36-1; H36-2; HFL1; HFL2; MGC104329; H factor (complement) -like 1; H factor (complement) -like 2; complement factor H-related 1 pseudogene; CFHR1 elisa kit
Reactivity
Human
Specificity
This assay has high sensitivity and excellent specificity for detection of human CFHR1. No significant cross-reactivity or interference between human CFHR1 and analogues was observed.
Sequence Length
330
Samples
Serum, plasma, tissue homogenates
Assay Type
Quantitative Competitive
Detection Range
25 ng/ml-1600 ng/ml
Sensitivity
< 12.5 ng/ml
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision
Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for CFHR1 elisa kit
Principle of the Assay: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been precoated with CFHR1. Standards or samples are added to the appropriate microtiter plate wells with Horseradish Peroxidase (HRP) conjugated antibody preparation specific for CFHR1. The competitive inhibition reaction is launched between with pre-coated CFHR1 and CFHR1 in samples. A substrate solution is added to the wells and the color develops in opposite to the amount of CFHR1 in the sample. The color development is stopped and the intensity of the color is measured.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
37,651 Da
NCBI Official Full Name
complement factor H-related protein 1
NCBI Official Synonym Full Names
complement factor H-related 1
NCBI Official Symbol
CFHR1
NCBI Official Synonym Symbols
CFHL; FHR1; HFL1; HFL2; CFHL1; H36-1; H36-2; CFHL1P; CFHR1P
NCBI Protein Information
complement factor H-related protein 1; H36; FHR-1; H-factor-like 1; h factor-like protein 1; H factor (complement)-like 1; H factor (complement)-like 2; complement factor H-related 1 pseudogene
UniProt Protein Name
Complement factor H-related protein 1
Protein Family
UniProt Gene Name
CFHR1
UniProt Synonym Gene Names
CFHL; CFHL1; CFHL1P; CFHR1P; FHR1; HFL1; HFL2; FHR-1; H-factor-like 1
UniProt Entry Name
FHR1_HUMAN
NCBI Description
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. [provided by RefSeq, Oct 2009]
Uniprot Description
CFHR1: Might be involved in complement regulation. Can associate with lipoproteins and may play a role in lipid metabolism.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 1q32
Cellular Component: extracellular space
Biological Process: complement activation
Disease: Macular Degeneration, Age-related, 1; Hemolytic Uremic Syndrome, Atypical, Susceptibility To, 1
Research Articles on CFHR1
Similar Products
Product Notes
The Human CFHR1 cfhr1 (Catalog #AAA916002) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA916002 ELISA Kit recognizes Human CFHR1. It is sometimes possible for the material contained within the vial of "complement factor H-related 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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