Goat Cholesteryl Ester Transfer Protein ELISA Kit | CETP elisa kit
Goat Cholesteryl Ester Transfer Protein ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is found in plasma, where it is involved in the transfer of cholesteryl ester from high density lipoprotein (HDL) to other lipoproteins. Defects in this gene are a cause of hyperalphalipoproteinemia 1 (HALP1). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
Uniprot Description
CETP: Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol. Defects in CETP are the cause of hyperalphalipoproteinemia type 1 (HALP1). Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL). Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Vesicle; Lipid-binding; Secreted
Chromosomal Location of Human Ortholog: 16q21
Cellular Component: extracellular space; extracellular region; vesicle
Molecular Function: lipid transporter activity; phospholipid transporter activity; cholesterol transporter activity; cholesterol binding; phosphatidylcholine binding; lipid binding; triglyceride binding
Biological Process: receptor-mediated endocytosis; cholesterol metabolic process; cholesterol transport; lipid homeostasis; lipoprotein metabolic process; lipid transport; phosphatidylcholine metabolic process; cholesterol homeostasis; triacylglycerol metabolic process; reverse cholesterol transport; phospholipid transport; triacylglycerol transport; transmembrane transport; phospholipid homeostasis
Disease: Hyperalphalipoproteinemia 1