Human cat eye syndrome chromosome region, candidate 2 ELISA Kit | CECR2 elisa kit

Human Cat eye syndrome critical region protein 2, CECR2 ELISA Kit

Cat. Num. AAA9337842

• Reactivity: Human
• Synonyms: cat eye syndrome chromosome region; candidate 2; Human Cat eye syndrome critical region protein 2; CECR2 ELISA Kit; Human Cat eye syndrome critical region protein 2 (CECR2) ELISA kit; KIAA1740; ; CECR2 elisa kit

• Reactivity: Human

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 586798134
• NCBI GeneID: 27443
• NCBI Accession #: NP_001276975.1
• NCBI GenBank Nucleotide #: NM_001290046.1
• UniProt Accession #: Q9BXF3; Q658Z4; Q96P58; Q9C0C3; A8MS90; A8MX16
• Molecular Weight: 164,213 Da
• NCBI Official Full Name: cat eye syndrome critical region protein 2 isoform 2
• NCBI Official Synonym Full Names: cat eye syndrome chromosome region, candidate 2
• NCBI Official Symbol: CECR2
• NCBI Protein Information: cat eye syndrome critical region protein 2
• UniProt Protein Name: Cat eye syndrome critical region protein 2
• Protein Family: Cat eye syndrome critical region protein
• UniProt Gene Name: CECR2
• UniProt Synonym Gene Names: KIAA1740
• UniProt Entry Name: CECR2_HUMAN

NCBI Description

This gene encodes a bromodomain-containing protein that is involved in chromatin remodeling, and may additionally play a role in DNA damage response. The encoded protein functions as part of an ATP-dependent complex that is involved in neurulation. This gene is a candidate gene for Cat Eye Syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

Uniprot Description

CECR2: Part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of chromatin structure in an ATP-dependent manner. May be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 22q11.2

Cellular Component: nucleus

Molecular Function: protein binding

Biological Process: vesicle-mediated transport; neural fold formation; inner ear receptor stereocilium organization and biogenesis; single fertilization; neural tube closure; ATP-dependent chromatin remodeling; cytokinesis; cytoskeleton organization and biogenesis; DNA fragmentation during apoptosis