ZW10 cdna clone
ZW10 cDNA Clone
Gene Names
ZW10; HZW10; KNTC1AP
Synonyms
ZW10; ZW10 cDNA Clone; ZW10 cdna clone
Sequence
ATGGCCTCGTTCGTGACAGAAGTTTTGGCACACTCCGGGAGGCTGGAAAAGGAGGATCTGGGGACCCGGATCAGCCGCCTGACCCGGCGGGTGGAGGAGATCAAGGGTGAGGTGTGCAATATGATTAGCAAGAAGTACAGTGAATTCCTGCCTAGCATGCAGAGCGCGCAGGGCCTGATTACCCAGGTGGATAAGCTATCTGAAGACATTGACCTGCTGAAATCCAGGATAGAGAGTGAGGTCCGCCGGGATCTTCACGTATCAACCGGTGAATTTACAGACTTAAAGCAGCAGTTGGAAAGAGACTCAGTTGTCCTAAGTTTGCTTAAACAGTTGCAGGAGTTTTCCACTGCTATTGAAGAATATAATTGTGCATTAACAGAGAAGAAGTATGTCACTGGTGCTCAGCGTCTGGAAGAGGCACAGAAATGCTTGAAGTTATTAAAATCCAGAAAATGCTTTGATTTAAAAATATTGAAATCTCTCAGCATGGAGCTCACAATACAGAAACAGAACATACTTTATCACCTTGGAGAAGAGTGGCAGAAGCTGATTGTATGGAAGTTCCCACCATCAAAAGATACCAGCAGTTTGGAATCTTACCTACAAACTGAACTTCATTTATACACTGAACAATCGCACAAAGAGGAGAAGACCCCTATGCCACCCATCAGTTCTGTCCTCTTGGCATTTTCTGTTCTTGGAGAACTACACAGCAAGCTTAAATCATTTGGTCAGATGCTGCTGAAGTATATCCTTAGGCCGCTGGCATCTTGCCCATCCCTTCATGCTGTGATAGAAAGCCAGCCTAACATAGTTATTATTCGTTTTGAATCTATAATGACTAACTTGGAATATCCATCACCATCTGAAGTTTTTACAAAGATCAGACTGGTACTAGAAGTGCTCCAGAAACAGCTTCTAGATTTGCCACTTGACACTGACCTGGAAAATGAAAAAACATCTACTGTCCCATTGGCTGAGATGCTTGGAGACATGATCTGGGAGGACTTGTCTGAGTGCCTCATCAAAAACTGTTTGGTTTATTCGATTCCAACAAATAGCAGCAAATTACAGCAATATGAAGAGATCATACAGTCCACTGAAGAATTTGAAAATGCCCTAAAGGAAATGAGATTTTTAAAAGGAGATACTACAGATTTGCTGAAATACGCTCGTAACATCAATTCTCATTTTGCAAACAAAAAGTGCCAGGATGTGATTGTGGCAGCCAGAAATCTAATGACCTCAGAAATTCATAACACTGTGAAGATTATTCCTGATTCTAAGATAAATGTGCCAGAGTTACCCACTCCTGATGAGGATAACAAACTGGAAGTACAGAAAGTATCCAATACTCAGTACCACGAAGTGATGAATTTAGAGCCTGAAAATACATTGGACCAACATTCCTTTTCCTTGCCCACATGCCGTATCAGTGAGTCTGTGAAGAAATTAATGGAACTCGCCTATCAGACTTTACTAGAGGCAACAACCAGTAGTGATCAATGTGCTGTTCAACTTTTCTACTCAGTGAGGAATATCTTCCATTTGTTCCATGATGTTGTACCAACATATCACAAGGAGAACCTTCAAAAACTTCCCCAGTTGGCTGCTATTCATCACAACAACTGTATGTACATTGCTCACCACTTGCTGACCCTCGGGCATCAGTTCAGATTGCGTCTTGCCCCCATTCTTTGTGATGGCACTGCTACTTTTGTGGATCTTGTACCTGGCTTCAGGAGACTTGGGACAGAATGCTTTTTGGCCCAAATGCGGGCACAGAAAGGTGAACTTCTGGAAAGATTATCAAGTGCTAGGAACTTTTCAAATATGGACGATGAAGAGAATTATTCTGCAGCAAGTAAAGCAGTCCGGCAGGTACTGCACCAACTAAAGAGACTTGGAATTGTGTGGCAGGATGTCCTGCCAGTGAATATATATTGCAAGGCTATGGGGACTTTACTCAATACAGCAATTTCTGAGGTCATTGGCAAAATTACTGCCCTAGAGTGA
Sequence Length
2019
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
76,807 Da
NCBI Official Full Name
Homo sapiens ZW10, kinetochore associated, homolog (Drosophila), mRNA
NCBI Official Synonym Full Names
zw10 kinetochore protein
NCBI Official Symbol
ZW10
NCBI Official Synonym Symbols
HZW10; KNTC1AP
NCBI Protein Information
centromere/kinetochore protein zw10 homolog
UniProt Protein Name
Centromere/kinetochore protein zw10 homolog
Protein Family
UniProt Gene Name
ZW10
UniProt Entry Name
ZW10_HUMAN
NCBI Description
This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. This protein is an essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. [provided by RefSeq, Aug 2011]
Uniprot Description
ZW10: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum. Belongs to the ZW10 family.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 11q23.2
Cellular Component: cytoplasm; cytosol; endoplasmic reticulum; kinetochore; kinetochore microtubule; membrane; nucleus; spindle pole
Molecular Function: centromeric DNA binding; protein binding
Biological Process: ER to Golgi vesicle-mediated transport; establishment of mitotic spindle orientation; Golgi organization and biogenesis; meiosis; mitotic cell cycle checkpoint; mitotic cell cycle spindle assembly checkpoint; mitotic metaphase plate congression; mitotic sister chromatid segregation; protein complex assembly; regulation of exit from mitosis; retrograde vesicle-mediated transport, Golgi to ER; sister chromatid cohesion
Research Articles on ZW10
Similar Products
Product Notes
The ZW10 zw10 (Catalog #AAA1275757) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGCCTCGT TCGTGACAGA AGTTTTGGCA CACTCCGGGA GGCTGGAAAA GGAGGATCTG GGGACCCGGA TCAGCCGCCT GACCCGGCGG GTGGAGGAGA TCAAGGGTGA GGTGTGCAAT ATGATTAGCA AGAAGTACAG TGAATTCCTG CCTAGCATGC AGAGCGCGCA GGGCCTGATT ACCCAGGTGG ATAAGCTATC TGAAGACATT GACCTGCTGA AATCCAGGAT AGAGAGTGAG GTCCGCCGGG ATCTTCACGT ATCAACCGGT GAATTTACAG ACTTAAAGCA GCAGTTGGAA AGAGACTCAG TTGTCCTAAG TTTGCTTAAA CAGTTGCAGG AGTTTTCCAC TGCTATTGAA GAATATAATT GTGCATTAAC AGAGAAGAAG TATGTCACTG GTGCTCAGCG TCTGGAAGAG GCACAGAAAT GCTTGAAGTT ATTAAAATCC AGAAAATGCT TTGATTTAAA AATATTGAAA TCTCTCAGCA TGGAGCTCAC AATACAGAAA CAGAACATAC TTTATCACCT TGGAGAAGAG TGGCAGAAGC TGATTGTATG GAAGTTCCCA CCATCAAAAG ATACCAGCAG TTTGGAATCT TACCTACAAA CTGAACTTCA TTTATACACT GAACAATCGC ACAAAGAGGA GAAGACCCCT ATGCCACCCA TCAGTTCTGT CCTCTTGGCA TTTTCTGTTC TTGGAGAACT ACACAGCAAG CTTAAATCAT TTGGTCAGAT GCTGCTGAAG TATATCCTTA GGCCGCTGGC ATCTTGCCCA TCCCTTCATG CTGTGATAGA AAGCCAGCCT AACATAGTTA TTATTCGTTT TGAATCTATA ATGACTAACT TGGAATATCC ATCACCATCT GAAGTTTTTA CAAAGATCAG ACTGGTACTA GAAGTGCTCC AGAAACAGCT TCTAGATTTG CCACTTGACA CTGACCTGGA AAATGAAAAA ACATCTACTG TCCCATTGGC TGAGATGCTT GGAGACATGA TCTGGGAGGA CTTGTCTGAG TGCCTCATCA AAAACTGTTT GGTTTATTCG ATTCCAACAA ATAGCAGCAA ATTACAGCAA TATGAAGAGA TCATACAGTC CACTGAAGAA TTTGAAAATG CCCTAAAGGA AATGAGATTT TTAAAAGGAG ATACTACAGA TTTGCTGAAA TACGCTCGTA ACATCAATTC TCATTTTGCA AACAAAAAGT GCCAGGATGT GATTGTGGCA GCCAGAAATC TAATGACCTC AGAAATTCAT AACACTGTGA AGATTATTCC TGATTCTAAG ATAAATGTGC CAGAGTTACC CACTCCTGAT GAGGATAACA AACTGGAAGT ACAGAAAGTA TCCAATACTC AGTACCACGA AGTGATGAAT TTAGAGCCTG AAAATACATT GGACCAACAT TCCTTTTCCT TGCCCACATG CCGTATCAGT GAGTCTGTGA AGAAATTAAT GGAACTCGCC TATCAGACTT TACTAGAGGC AACAACCAGT AGTGATCAAT GTGCTGTTCA ACTTTTCTAC TCAGTGAGGA ATATCTTCCA TTTGTTCCAT GATGTTGTAC CAACATATCA CAAGGAGAAC CTTCAAAAAC TTCCCCAGTT GGCTGCTATT CATCACAACA ACTGTATGTA CATTGCTCAC CACTTGCTGA CCCTCGGGCA TCAGTTCAGA TTGCGTCTTG CCCCCATTCT TTGTGATGGC ACTGCTACTT TTGTGGATCT TGTACCTGGC TTCAGGAGAC TTGGGACAGA ATGCTTTTTG GCCCAAATGC GGGCACAGAA AGGTGAACTT CTGGAAAGAT TATCAAGTGC TAGGAACTTT TCAAATATGG ACGATGAAGA GAATTATTCT GCAGCAAGTA AAGCAGTCCG GCAGGTACTG CACCAACTAA AGAGACTTGG AATTGTGTGG CAGGATGTCC TGCCAGTGAA TATATATTGC AAGGCTATGG GGACTTTACT CAATACAGCA ATTTCTGAGG TCATTGGCAA AATTACTGCC CTAGAGTGA. It is sometimes possible for the material contained within the vial of "ZW10, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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