ZNF521 cdna clone
ZNF521 cDNA Clone
Gene Names
ZNF521; EHZF; Evi3
Synonyms
ZNF521; ZNF521 cDNA Clone; ZNF521 cdna clone
Sequence
atgtctcgccgcaagcaagcgaaaccgagatccctcaaagaccccaactgtaaacttgaagacaagactgaagatggagaggcactagattgtaagaagaggccggaagacggggaggagttggaagacgaagctgtgcacagctgtgacagctgcctccaggtgtttgaatcgctgagcgatatcacagaacacaagattaatcaatgtcaactgacagatggagtggatgttgaagatgatccgacttgctcttggccagcttcctcaccttctagcaaggatcagacttcccctagccatggagaaggttgcgattttggagaggaagaaggtggccctgggcttccatacccgtgtcaattctgtgacaagtcgtttagccgcctcagctacctaaagcaccatgagcagagtcacagtgacaaactgcctttcaaatgcacctactgcagtaggctgttcaaacacaagcgcagccgagatcgccacataaaactccacaccggggacaagaagtaccactgcagtgaatgtgatgctgcgttttccagaagtgatcacttgaagatccacttaaagactcacacgtccaacaagccatataaatgtgccatttgtcgccgtgggtttctgtcctctagttccttacacggacacatgcaggttcatgagaggaacaaggacggctctcagtccggttccaggatggaggactggaagatgaaggacactcagaagtgcagtcagtgtgaggaaggctttgacttcccggaagacctccaaaaacacattgcagagtgccaccccgaatgctccccaaatgaggaccgagcggccctccagtgtgtctactgccacgagctcttcgtagaggagacctccctcatgaaccacatggagcaggtgcatagcggggagaagaagaactcatgcagcatttgttctgagagtttccacacagttgaggaactgtacagccacatggacagtcaccagcaaccggagtcatgcaatcacagcaacagcccttccctggtcacggtgggctatacctccgtgtccagtacgactccagattccaacctctcagtggacagctcaaccatggtggaagctgccccgccaatcccaaagagtcgagggaggaagagggccgctcaacaaacccctgacatgactggtccctcgagtaaacaagcaaaagttacctacagctgtatttactgcaacaaacaattattttcaagtcttgcagttctgcagattcacctgaaaactatgcacttagataagccagaacaggcccatatttgtcagtattgcttggaggtcctgccctcactctataacctaaatgaacatcttaagcaagtgcatgaagctcaggacccaggtctgattgtttctgccatgcctgccattgtctaccagtgtaacttctgttccgaagttgtcaacgacctcaacactcttcaggaacacatccgatgttctcatggatttgcaaaccctgcagctaaagatagtaatgcattcttttgtccccattgctatatggggtttctcactgactcttccctggaagagcatattagacaggttcattgtgacctcagtggctcccgatttgggtctccagtgcttgggactcccaaagaaccagtagtagaagtctattcttgttcctattgtacaaattcgccaatattcaacagcgttcttaaactgaacaagcatatcaaagagaatcataaaaacattcccttggccctgaattatatccacaatgggaagaaatccagggccttaagccccctatctcctgtggccatagagcagacatctcttaagatgatgcaggcagtaggaggtgcacctgcacgtcccactggagaatatatctgtaatcaatgtggtgctaagtacacatccctagacagctttcagactcacctaaaaactcatctcgacactgtgcttccaaaattgacctgtcctcagtgcaacaaggaattccccaaccaagaatccttgctgaagcatgttaccattcactttatgatcacttcaacgtattacatctgtgagagttgtgacaagcaattcacatcagtggatgaccttcagaaacacctgctggacatgcacacctttgtcttctttcgctgcaccctctgccaggaagtttttgactcaaaagtctccattcagctccacttggctgtgaagcacagtaacgaaaagaaagtctataggtgcacatcttgcaactgggacttccgcaacgaaactgacttgcagctccatgtgaaacacaaccacctggaaaaccaagggaaagtgcataagtgcattttctgcggtgagtcctttggcaccgaggtggagctgcaatgccacatcaccactcacagtaagaagtacaactgcaagttctgtagcaaagccttccatgcgatcattttgttagaaaaacacttgcgagaaaaacactgtgtattcgaaaccaagacacccaactgtggaacaaatggagcttccgagcaagtgcagaaagaggaagtggagctgcagactttgctgaccaacagccaggagtcccacaacagtcacgatgggagcgaagaagacgttgacacctctgagcctatgtacggctgcgacatttgtggggcagcctacactatggaaactttgctgcagaatcaccagctccgagaccacaacatcagacctggagaaagtgccatcgtgaaaaagaaagctgagctcattaaagggaattacaagtgcaacgtgtgctctcgaaccttcttctccgaaaatggcctccgggaacatatgcagacccacctaggccctgtcaaacactacatgtgccctatttgcggagagcggtttccctcccttttaactcttactgaacacaaagtcacgcatagtaagagtcttgatactggaaactgccggatttgcaagatgcctctccagagtgaagaggagtttttagagcattgccaaatgcaccctgacttgaggaattccctgacaggctttcgctgcgtggtgtgcatgcagacagtgacctccaccttggaactcaaaatccatgggacgttccacatgcaaaagacagggaatgggtctgcagttcagaccacagggcggggccagcacgtccaaaaactgtataagtgcgcatcttgcctcaaagaattccgttccaagcaagatctggtgaaacttgatatcaatggcctgccatatggtctgtgtgccggctgcgtgaatctcagtaagagcgccagcccaggcattaacgtccctcccggcacgaatagaccaggcttgggccagaatgagaatctgagtgccattgaggggaaaggcaaggtggggggactgaagacacgctgctctagctgcaacgttaagtttgagtctgaaagtgaactccagaaccacatccaaaccatccaccgagagctcgtgccagacagcaacagcacacagttgaaaacgccccaagtatcaccaatgcccagaatcagtccctcccagtcggatgagaagaagacctatcaatgcatcaaatgtcagatggttttctacaatgaatgggatattcaggttcatgttgcaaatcacatgattgatgaaggactgaaccatgaatgcaaactctgcagccagacctttgactctcctgccaaactccagtgccacctgatagagcacagcttcgaagggatgggaggcaccttcaagtgtccagtctgctttacagtatttgttcaagcaaacaagttgcagcagcatattttctctgcccatggacaagaagacaagatctatgactgtacacaatgtccacagaagtttttcttccaaacagagctgcagaatcatacaatgacccaacacagcagttag
Sequence Length
3936
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
147,866 Da
NCBI Official Full Name
Homo sapiens zinc finger protein 521, mRNA
NCBI Official Synonym Full Names
zinc finger protein 521
NCBI Official Symbol
ZNF521
NCBI Official Synonym Symbols
EHZF; Evi3
NCBI Protein Information
zinc finger protein 521
UniProt Protein Name
Zinc finger protein 521
Protein Family
UniProt Gene Name
ZNF521
UniProt Synonym Gene Names
EHZF; LIP3
UniProt Entry Name
ZN521_HUMAN
Uniprot Description
ZNF521: Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage; this interaction preventing EBF1 to bind DNA and activate target genes. A chromosomal aberration involving ZNF521 is found in acute lymphoblastic leukemia. Translocation t(9;18)(p13;q11.2) with PAX5. The translocation generates the PAX5-ZNF521 oncogene consisting of the N-terminus part of PAX5 and the C-terminus part of ZNF521. Belongs to the krueppel C2H2-type zinc-finger protein family.
Protein type: DNA-binding; Oncoprotein; C2H2-type zinc finger protein; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 18q11.2
Cellular Component: nucleus
Molecular Function: protein domain specific binding
Research Articles on ZNF521
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Product Notes
The ZNF521 znf521 (Catalog #AAA1271582) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgtctcgcc gcaagcaagc gaaaccgaga tccctcaaag accccaactg taaacttgaa gacaagactg aagatggaga ggcactagat tgtaagaaga ggccggaaga cggggaggag ttggaagacg aagctgtgca cagctgtgac agctgcctcc aggtgtttga atcgctgagc gatatcacag aacacaagat taatcaatgt caactgacag atggagtgga tgttgaagat gatccgactt gctcttggcc agcttcctca ccttctagca aggatcagac ttcccctagc catggagaag gttgcgattt tggagaggaa gaaggtggcc ctgggcttcc atacccgtgt caattctgtg acaagtcgtt tagccgcctc agctacctaa agcaccatga gcagagtcac agtgacaaac tgcctttcaa atgcacctac tgcagtaggc tgttcaaaca caagcgcagc cgagatcgcc acataaaact ccacaccggg gacaagaagt accactgcag tgaatgtgat gctgcgtttt ccagaagtga tcacttgaag atccacttaa agactcacac gtccaacaag ccatataaat gtgccatttg tcgccgtggg tttctgtcct ctagttcctt acacggacac atgcaggttc atgagaggaa caaggacggc tctcagtccg gttccaggat ggaggactgg aagatgaagg acactcagaa gtgcagtcag tgtgaggaag gctttgactt cccggaagac ctccaaaaac acattgcaga gtgccacccc gaatgctccc caaatgagga ccgagcggcc ctccagtgtg tctactgcca cgagctcttc gtagaggaga cctccctcat gaaccacatg gagcaggtgc atagcgggga gaagaagaac tcatgcagca tttgttctga gagtttccac acagttgagg aactgtacag ccacatggac agtcaccagc aaccggagtc atgcaatcac agcaacagcc cttccctggt cacggtgggc tatacctccg tgtccagtac gactccagat tccaacctct cagtggacag ctcaaccatg gtggaagctg ccccgccaat cccaaagagt cgagggagga agagggccgc tcaacaaacc cctgacatga ctggtccctc gagtaaacaa gcaaaagtta cctacagctg tatttactgc aacaaacaat tattttcaag tcttgcagtt ctgcagattc acctgaaaac tatgcactta gataagccag aacaggccca tatttgtcag tattgcttgg aggtcctgcc ctcactctat aacctaaatg aacatcttaa gcaagtgcat gaagctcagg acccaggtct gattgtttct gccatgcctg ccattgtcta ccagtgtaac ttctgttccg aagttgtcaa cgacctcaac actcttcagg aacacatccg atgttctcat ggatttgcaa accctgcagc taaagatagt aatgcattct tttgtcccca ttgctatatg gggtttctca ctgactcttc cctggaagag catattagac aggttcattg tgacctcagt ggctcccgat ttgggtctcc agtgcttggg actcccaaag aaccagtagt agaagtctat tcttgttcct attgtacaaa ttcgccaata ttcaacagcg ttcttaaact gaacaagcat atcaaagaga atcataaaaa cattcccttg gccctgaatt atatccacaa tgggaagaaa tccagggcct taagccccct atctcctgtg gccatagagc agacatctct taagatgatg caggcagtag gaggtgcacc tgcacgtccc actggagaat atatctgtaa tcaatgtggt gctaagtaca catccctaga cagctttcag actcacctaa aaactcatct cgacactgtg cttccaaaat tgacctgtcc tcagtgcaac aaggaattcc ccaaccaaga atccttgctg aagcatgtta ccattcactt tatgatcact tcaacgtatt acatctgtga gagttgtgac aagcaattca catcagtgga tgaccttcag aaacacctgc tggacatgca cacctttgtc ttctttcgct gcaccctctg ccaggaagtt tttgactcaa aagtctccat tcagctccac ttggctgtga agcacagtaa cgaaaagaaa gtctataggt gcacatcttg caactgggac ttccgcaacg aaactgactt gcagctccat gtgaaacaca accacctgga aaaccaaggg aaagtgcata agtgcatttt ctgcggtgag tcctttggca ccgaggtgga gctgcaatgc cacatcacca ctcacagtaa gaagtacaac tgcaagttct gtagcaaagc cttccatgcg atcattttgt tagaaaaaca cttgcgagaa aaacactgtg tattcgaaac caagacaccc aactgtggaa caaatggagc ttccgagcaa gtgcagaaag aggaagtgga gctgcagact ttgctgacca acagccagga gtcccacaac agtcacgatg ggagcgaaga agacgttgac acctctgagc ctatgtacgg ctgcgacatt tgtggggcag cctacactat ggaaactttg ctgcagaatc accagctccg agaccacaac atcagacctg gagaaagtgc catcgtgaaa aagaaagctg agctcattaa agggaattac aagtgcaacg tgtgctctcg aaccttcttc tccgaaaatg gcctccggga acatatgcag acccacctag gccctgtcaa acactacatg tgccctattt gcggagagcg gtttccctcc cttttaactc ttactgaaca caaagtcacg catagtaaga gtcttgatac tggaaactgc cggatttgca agatgcctct ccagagtgaa gaggagtttt tagagcattg ccaaatgcac cctgacttga ggaattccct gacaggcttt cgctgcgtgg tgtgcatgca gacagtgacc tccaccttgg aactcaaaat ccatgggacg ttccacatgc aaaagacagg gaatgggtct gcagttcaga ccacagggcg gggccagcac gtccaaaaac tgtataagtg cgcatcttgc ctcaaagaat tccgttccaa gcaagatctg gtgaaacttg atatcaatgg cctgccatat ggtctgtgtg ccggctgcgt gaatctcagt aagagcgcca gcccaggcat taacgtccct cccggcacga atagaccagg cttgggccag aatgagaatc tgagtgccat tgaggggaaa ggcaaggtgg ggggactgaa gacacgctgc tctagctgca acgttaagtt tgagtctgaa agtgaactcc agaaccacat ccaaaccatc caccgagagc tcgtgccaga cagcaacagc acacagttga aaacgcccca agtatcacca atgcccagaa tcagtccctc ccagtcggat gagaagaaga cctatcaatg catcaaatgt cagatggttt tctacaatga atgggatatt caggttcatg ttgcaaatca catgattgat gaaggactga accatgaatg caaactctgc agccagacct ttgactctcc tgccaaactc cagtgccacc tgatagagca cagcttcgaa gggatgggag gcaccttcaa gtgtccagtc tgctttacag tatttgttca agcaaacaag ttgcagcagc atattttctc tgcccatgga caagaagaca agatctatga ctgtacacaa tgtccacaga agtttttctt ccaaacagag ctgcagaatc atacaatgac ccaacacagc agttag. It is sometimes possible for the material contained within the vial of "ZNF521, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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