ZFYVE16 cdna clone
ZFYVE16 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an endosomal protein that belongs to the FYVE zinc finger family of proteins. The encoded protein is thought to regulate membrane trafficking in the endosome. This protein functions as a scaffold protein in the transforming growth factor-beta signaling pathway and is involved in positive and negative feedback regulation of the bone morphogenetic protein signaling pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Uniprot Description
endofin: May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Lipid-binding
Chromosomal Location of Human Ortholog: 5q14
Cellular Component: cytoplasm; early endosome; early endosome membrane; intracellular membrane-bound organelle
Molecular Function: phosphatidylinositol binding; phosphatidylinositol-3,4,5-triphosphate binding; protein binding; protein transporter activity
Biological Process: BMP signaling pathway; endosome transport; protein targeting to lysosome; regulation of endocytosis
Research Articles on ZFYVE16
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Product Notes
The ZFYVE16 zfyve16 (Catalog #AAA1278676) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggacagtt attttaaagc agctgtcagt gacttggaca aactccttga tgattttgaa cagaacccag atgaacaaga ttatctccaa gatgtacaaa atgcatatga ttctaaccac tgctcagttt cttcagagtt ggcttcctca cagcgaactt cattgctccc aaaagaccaa gagtgcgtta atagttgtgc ctcatcagaa acaagctatg gaacaaatga gagttccctg aataaaaaaa cactcaaggg acttacttct atacaaaatg aaaaaaatgt aacaggactt gatcttcttt cttctgtgga tggtggtact tcagatgaaa tccagccgtt atatatggga cgatgtagta aacctatctg tgatctgata agtgacatgg gtaacttagt tcatgcaacc aatagtgaag aagatattaa aaaattattg ccagatgatt ttaagtctaa tgcagattcc ttgattggat tggatttatc ttcagtgtca gatactccct gtgtttcttc aacagaccat gatagcgata ctgtcagaga acaacagaat gataccagtt ctgaattaca aaatagagaa atcggaggaa tcaaagaatt gggtataaaa gtagatacaa cactttcaga ttcctataat tacagtggaa cagaaaattt aaaagataaa aagatcttta atcagttaga atcaattgtt gattttaaca tgtcatctgc tttgactcga caaagttcca aaatgtttca tgccaaagac aagctacaac acaagagcca gccatgtgga ttactaaaag atgttggctt agtaaaagag gaagtagatg tggcagtcat aactgccgca gaatgtttaa aagaagaggg caagacaagt gctttgacct gcagccttcc gaaaaatgaa gatttatgct taaatgattc aaattcaaga gatgaaaatt tcaaattacc tgacttttcc tttcaggaag ataagactgt tataaaacaa tctgcacaag aagactcaaa aagtttagac cttaaggata atgatgtaat ccaagattcc tcttcagctt tacatgtttc cagtaaagat gtgccgtcct cattgtcctg tcttcctgcg tctgggtcta tgtgtggatc attaattgaa agtaaagcac ggggtgattt tttacctcag catgaacata aagataatat acaagatgca gtgactatac atgaagaaat acagaacagt gttgttctag gtggggaacc attcaaagag aatgatcttt tgaaacagga aaaatgtaaa agcatactcc ttcagtcatt aattgaaggg atggaagaca gaaagataga tcctgaccag acagtaatca gagctgagtc tttggatggt ggtgacacca gttctacagt tgtagaatct caagaggggc tttctggcac tcatgtccca gagtcttctg attgttgtga aggttttatt aatacttttt caagcaatga tatggatggg caagacttag attactttaa tattgatgaa ggcgcaaaaa gtggcccact aattagtgat gctgaacttg atgcctttct gacagaacag tatcttcaga ccactaacat aaagtctttt gaagaaaatg taaatgactc taaatcgcaa atgaatcaga tagatatgaa aggcttagat gatggaaaca tcaataatat atatttcaat gcagaagcag gagctattgg ggaaagtcat ggtattaata taatttgtga aacagttgat aaacaaaata caatagaaaa tggcctttct ttaggagaaa aaagcactat tccagttcaa caagggttac ctaccagtaa gtctgagatt acaaatcaat tatcagtctc tgatattaac agtcaatctg ttggaggggc cagacctaag caattgttta gccttccatc aagaacaagg agttcaaagg acctgaataa gccagatgtt ccagatacaa tagaaagtga acccagcaca gcagataccg ttgttccaat cacttgtgct atagattcta cagctgatcc acaggttagc ttcaactcta attacattga tatagaaagt aattctgaag gtggatctag tttcgtaact gcaaatgaag attctgtacc tgaaaacact tgcaaagaag gcttggtttt gggccagaaa cagcctactt gggttcctga ttcagaagct ccaaactgta tgaactgcca agtcaaattt acttttacca aacggcgaca ccattgccga gcatgtggga aagtattttg tggtgtctgt tgtaatagga agtgtaaact gcaatatcta gaaaaggaag caagagtatg tgtagtctgc tatgaaacta ttagtaaagg tgagtgttaa. It is sometimes possible for the material contained within the vial of "ZFYVE16, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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