XRCC6BP1 cdna clone
XRCC6BP1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
Uniprot Description
XRCC6BP1: Belongs to the peptidase M76 family.
Protein type: DNA repair, damage; EC 3.4.24.-; Protease
Chromosomal Location of Human Ortholog: 12q14.1
Cellular Component: intracellular membrane-bound organelle; plasma membrane
Molecular Function: DNA-dependent protein kinase activity
Biological Process: double-strand break repair via nonhomologous end joining
Research Articles on XRCC6BP1
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Product Notes
The XRCC6BP1 atp23 (Catalog #AAA1275188) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggcgggag ctccggacga gcgccggcgg ggccccgcgg caggggagca gctgcagcag caacacgtct cttgccaggt cttccccgag cgtctggccc aggggaatcc ccagcaaggg ttcttctcca gcttcttcac ctgcaaccag aagtgccagc ttaggctcct gaagacgctg gagacaagta ggagccatga cctggaggct gtggttccac agaatgggtc tgagaccggg tgggcgagga agggcctggg caacacctgg ccaggggctt caggttcagc acagagtcta gacagactgg gcatcatggg ggctgggttg ggagcctga. It is sometimes possible for the material contained within the vial of "XRCC6BP1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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