WNT2B cdna clone
WNT2B cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Uniprot Description
WNT2B: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May be involved in normal development or differentiation as well as in carcinogenesis. Belongs to the Wnt family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 1p13
Cellular Component: extracellular region; extracellular space
Molecular Function: frizzled binding
Biological Process: cell fate commitment; chondrocyte differentiation; forebrain regionalization; lens development in camera-type eye; male gonad development; neuron differentiation; Wnt receptor signaling pathway
Research Articles on WNT2B
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Product Notes
The WNT2B wnt2b (Catalog #AAA1275887) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGCTGAGAC CGGGTGGTGC GGAGGAAGCT GCGCAGCTCC CGCTTCGGCG CGCCAGCGCC CCGGTCCCTG TGCCGTCGCC CGCGGCCCCC GACGGCTCCC GGGCTTCGGC CCGCCTAGGT CTTGCCTGCC TTCTGCTCCT GCTGCTGCTG ACGCTGCCGG CCCGCGTAGA CACGTCCTGG TGGTACATTG GGGCACTGGG GGCACGAGTG ATCTGTGACA ATATCCCTGG TTTGGTGAGC CGGCAGCGGC AGCTGTGCCA GCGTTACCCA GACATCATGC GTTCAGTGGG CGAGGGTGCC CGAGAATGGA TCCGAGAGTG TCAGCACCAA TTCCGCCACC ACCGCTGGAA CTGTACCACC CTGGACCGGG ACCACACCGT CTTTGGCCGT GTCATGCTCA GAAGTAGCCG AGAGGCAGCT TTTGTATATG CCATCTCATC AGCAGGGGTA GTCCACGCTA TTACTCGCGC CTGTAGCCAG GGTGAACTGA GTGTGTGCAG CTGTGACCCC TACACCCGTG GCCGACACCA TGACCAGCGT GGGGACTTTG ACTGGGGTGG CTGCAGTGAC AACATCCACT ACGGTGTCCG TTTTGCCAAG GCCTTCGTGG ATGCCAAGGA GAAGAGGCTT AAGGATGCCC GGGCCCTCAT GAACTTACAT AATAACCGCT GTGGTCGCAC GGCTGTGCGG CGGTTTCTGA AGCTGGAGTG TAAGTGCCAT GGCGTGAGTG GTTCCTGTAC TCTGCGCACC TGCTGGCGTG CACTCTCAGA TTTCCGCCGC ACAGGTGATT ACCTGCGGCG ACGCTATGAT GGGGCTGTGC AGGTGATGGC CACCCAAGAT GGTGCCAACT TCACCGCAGC CCGCCAAGGC TATCGCCGTG CCACCCGGAC TGATCTTGTC TACTTTGACA ACTCTCCAGA TTACTGTGTC TTGGACAAGG CTGCAGGTTC CCTAGGCACT GCAGGCCGTG TCTGCAGCAA GACATCAAAA GGAACAGACG GTTGTGAAAT CATGTGCTGT GGCCGAGGGT ACGACACAAC TCGAGTCACC CGTGTTACCC AGTGTGAGTG CAAATTCCAC TGGTGCTGTG CTGTACGGTG CAAGGAATGC AGAAATACTG TGGACGTCCA TACTTGCAAA GCCCCCAAGA AGGCAGAGTG GCTGGACCAA ACCTGA. It is sometimes possible for the material contained within the vial of "WNT2B, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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