UBR3 cdna clone
UBR3 cDNA Clone
Gene Names
UBR3; ZNF650
Synonyms
UBR3; UBR3 cDNA Clone; UBR3 cdna clone
Sequence
ATGGAAACTGCAATGGATGTTGATTCTCCTGAGAATGATATTCCTATGGAGATCACCACGGCAGAACCACAGGTTTCCGAGGCAGTATATGACTGTGTTATTTGTGGACAGAGTGGCCCCTCCTCTGAAGATCGACCTACTGGATTAGTTGTACTGTTACAAGCATCCTCAGTTTTGGGGCAGTGCCGTGACAATGTTGAGCCAAAAAAGTTGCCGATCAGTGAAGAGGAGCAGATTTACCCTTGGGATACCTGTGCAGCCGTTCATGATGTGAGGCTTTCATTATTACAGCGTTATTTTAAGGATAGTTCATGTCTCTTGGCAGTATCAATTGGCTGGGAAGGAGGTGTTTATGTACAAACCTGTGGTCACACATTACATATAGATTGTCATAAATCTTACATGGAATCATTACGGAATGACCAGGTTCTTCAGGGCTTCTCGGTGGACAAAGGAGAATTCACGTGTCCACTCTGTAGGCAGTTTGCTAACAGTGTTCTTCCATGTTATCCTGGAAGCAATGTGGAAAATAACCCTTGGCAACGTCCTAGCAACAAAAGCATACAAGATCTCATAAAGGAAGTGGAGGAGCTGCAGGGACGACCGGGAGCTTTCCCATCAGAAACAAATTTAAGTAAAGAAATGGAATCTGTAATGAAAGATATAAAAAATACCACTCAGAAGAAATATAGAGACTATAGCAAGACCCCGGGCTCACCAGACAATGATTTTCTCTTTATGTACTCTGTTGCTAGAACCAATTTAGAACTTGAATTGATTCATCGAGGAGGCAATTTGTGTTCAGGTGGTGCAAGCACAGCTGGCAAAAGGTCTTGTTTAAATCAGCTGTTTCATGTATTAGCCTTGCACATGCGGCTTTATAGCATTGACTCTGAGTATAATCCCTGGAGAAAGCTCACCCAGTTAGAAGAGATGAATCCACAGCTGGGATATGAAGAACAACAGCCTGAGGTTCCAATTCTTTATCATGATGTAACATCCCTTTTGCTCATCCAGATCTTAATGATGCCACAACCCTTACGCAAAGACCACTTTACCTGCATTGTGAAGGTACTTTTTACCCTACTGTACACACAGGCTCTTGCAGCACTCTCAGTTAAATGCAGCGAAGAAGATAGGTCAGCCTGGAAACACGCGGGAGCTCTCAAAAAGAGTACATGTGATGCAGAAAAGTCTTACGAAGTATTACTGAGCTTTGTGATAAGTGAACTATTTAAAGGAAAGTTATACCATGAAGAAGGAACTCAGGAATGTGCAATGGTTAACCCTATTGCTTGGTCTCCTGAATCCATGGAAAAATGCTTACAGGACTTCTGCTTACCTTTTCTCAGAATCACCAGCCTTCTTCAGCACCACCTTTTTGGGGAAGATTTACCTAGCTGCCAGGAAGAAGAAGAATTTTCAGTTCTTGCCAGCTGCCTGGGACTTCTGCCAACGTTTTACCAAACAGAACATCCATTCATCAGTGCCTCCTGTCTGGATTGGCCAGTTCCAGCATTTGATATTATAACTCAGTGGTGTTTTGAGATAAAATCATTTACTGAAAGACATGCAGAACAAGGAAAGGCCTTGCTTATCCAAGAGTCAAAATGGAAATTACCACACCTACTACAGTTGCCTGAGAATTATAACACCATTTTTCAGTACTACCACAGAAAAACCTGTAGTGTCTGCACCAAGGTTCCTAAAGATCCTGCTGTTTGCCTTGTGTGTGGTACTTTTGTATGCCTGAAAGGACTTTGCTGCAAGCAACAAAGTTACTGTGAATGTGTACTGCACTCTCAGAACTGTGGTGCAGGAACAGGTATTTTCCTTTTGATCAATGCATCGGTAATTATCATCATTCGAGGTCACCGCTTCTGCCTCTGGGGTTCCGTGTATTTGGATGCTCATGGAGAGGAAGACCGGGATCTTAGGCGAGGCAAACCTCTCTACATTTGTAAGGAAAGATACAAAGTTCTTGAGCAACAGTGGATTTCTCATACTTTTGATCACATCAATAAAAGATGGGGTCCACATTACAATGGGCTGTGA
Sequence Length
2055
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
215,971 Da
NCBI Official Full Name
Homo sapiens cDNA clone IMAGE:40036320, containing frame-shift errors
NCBI Official Synonym Full Names
ubiquitin protein ligase E3 component n-recognin 3 (putative)
NCBI Official Symbol
UBR3
NCBI Official Synonym Symbols
ZNF650
NCBI Protein Information
E3 ubiquitin-protein ligase UBR3
UniProt Protein Name
E3 ubiquitin-protein ligase UBR3
Protein Family
UniProt Gene Name
UBR3
UniProt Synonym Gene Names
KIAA2024; ZNF650
UniProt Entry Name
UBR3_HUMAN
Uniprot Description
UBR3: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Does not bind to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Belongs to the UBR1 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Ligase; EC 6.3.2.19; Ubiquitin ligase; Membrane protein, integral; Membrane protein, multi-pass; Ubiquitin conjugating system; EC 6.3.2.-
Chromosomal Location of Human Ortholog: 2q31.1
Cellular Component: cytoplasm; ubiquitin ligase complex
Molecular Function: ubiquitin-protein ligase activity
Biological Process: embryonic development; sensory perception of smell; suckling behavior; ubiquitin-dependent protein catabolic process
Research Articles on UBR3
1. UBR3/6 regulate cardiomyocyte Nav 1.5 channel protein levels via the ubiquitin-proteasome pathway.
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Product Notes
The UBR3 ubr3 (Catalog #AAA1274116) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGAAACTG CAATGGATGT TGATTCTCCT GAGAATGATA TTCCTATGGA GATCACCACG GCAGAACCAC AGGTTTCCGA GGCAGTATAT GACTGTGTTA TTTGTGGACA GAGTGGCCCC TCCTCTGAAG ATCGACCTAC TGGATTAGTT GTACTGTTAC AAGCATCCTC AGTTTTGGGG CAGTGCCGTG ACAATGTTGA GCCAAAAAAG TTGCCGATCA GTGAAGAGGA GCAGATTTAC CCTTGGGATA CCTGTGCAGC CGTTCATGAT GTGAGGCTTT CATTATTACA GCGTTATTTT AAGGATAGTT CATGTCTCTT GGCAGTATCA ATTGGCTGGG AAGGAGGTGT TTATGTACAA ACCTGTGGTC ACACATTACA TATAGATTGT CATAAATCTT ACATGGAATC ATTACGGAAT GACCAGGTTC TTCAGGGCTT CTCGGTGGAC AAAGGAGAAT TCACGTGTCC ACTCTGTAGG CAGTTTGCTA ACAGTGTTCT TCCATGTTAT CCTGGAAGCA ATGTGGAAAA TAACCCTTGG CAACGTCCTA GCAACAAAAG CATACAAGAT CTCATAAAGG AAGTGGAGGA GCTGCAGGGA CGACCGGGAG CTTTCCCATC AGAAACAAAT TTAAGTAAAG AAATGGAATC TGTAATGAAA GATATAAAAA ATACCACTCA GAAGAAATAT AGAGACTATA GCAAGACCCC GGGCTCACCA GACAATGATT TTCTCTTTAT GTACTCTGTT GCTAGAACCA ATTTAGAACT TGAATTGATT CATCGAGGAG GCAATTTGTG TTCAGGTGGT GCAAGCACAG CTGGCAAAAG GTCTTGTTTA AATCAGCTGT TTCATGTATT AGCCTTGCAC ATGCGGCTTT ATAGCATTGA CTCTGAGTAT AATCCCTGGA GAAAGCTCAC CCAGTTAGAA GAGATGAATC CACAGCTGGG ATATGAAGAA CAACAGCCTG AGGTTCCAAT TCTTTATCAT GATGTAACAT CCCTTTTGCT CATCCAGATC TTAATGATGC CACAACCCTT ACGCAAAGAC CACTTTACCT GCATTGTGAA GGTACTTTTT ACCCTACTGT ACACACAGGC TCTTGCAGCA CTCTCAGTTA AATGCAGCGA AGAAGATAGG TCAGCCTGGA AACACGCGGG AGCTCTCAAA AAGAGTACAT GTGATGCAGA AAAGTCTTAC GAAGTATTAC TGAGCTTTGT GATAAGTGAA CTATTTAAAG GAAAGTTATA CCATGAAGAA GGAACTCAGG AATGTGCAAT GGTTAACCCT ATTGCTTGGT CTCCTGAATC CATGGAAAAA TGCTTACAGG ACTTCTGCTT ACCTTTTCTC AGAATCACCA GCCTTCTTCA GCACCACCTT TTTGGGGAAG ATTTACCTAG CTGCCAGGAA GAAGAAGAAT TTTCAGTTCT TGCCAGCTGC CTGGGACTTC TGCCAACGTT TTACCAAACA GAACATCCAT TCATCAGTGC CTCCTGTCTG GATTGGCCAG TTCCAGCATT TGATATTATA ACTCAGTGGT GTTTTGAGAT AAAATCATTT ACTGAAAGAC ATGCAGAACA AGGAAAGGCC TTGCTTATCC AAGAGTCAAA ATGGAAATTA CCACACCTAC TACAGTTGCC TGAGAATTAT AACACCATTT TTCAGTACTA CCACAGAAAA ACCTGTAGTG TCTGCACCAA GGTTCCTAAA GATCCTGCTG TTTGCCTTGT GTGTGGTACT TTTGTATGCC TGAAAGGACT TTGCTGCAAG CAACAAAGTT ACTGTGAATG TGTACTGCAC TCTCAGAACT GTGGTGCAGG AACAGGTATT TTCCTTTTGA TCAATGCATC GGTAATTATC ATCATTCGAG GTCACCGCTT CTGCCTCTGG GGTTCCGTGT ATTTGGATGC TCATGGAGAG GAAGACCGGG ATCTTAGGCG AGGCAAACCT CTCTACATTT GTAAGGAAAG ATACAAAGTT CTTGAGCAAC AGTGGATTTC TCATACTTTT GATCACATCA ATAAAAGATG GGGTCCACAT TACAATGGGC TGTGA. It is sometimes possible for the material contained within the vial of "UBR3, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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