UBA7 cdna clone
UBA7 cDNA Clone
Gene Names
UBA7; D8; UBE2; UBA1B; UBE1L
Synonyms
UBA7; UBA7 cDNA Clone; UBA7 cdna clone
Sequence
atggatgccctggacgcttcgaagctactggatgaggagctgtattcaagacagctgtatgtgctgggctcacctgccatgcagaggattcagggagccagggtcctggtgtcaggcctgcagggcctgggggccgaggtggccaagaacttggttctgatgggtgtgggcagcctcactctgcatgatccccaccccacctgctggtccgacctggctgcccagtttctcctctcagagcaggacttggaaaggagcagagccgaggcctctcaagagctcttggctcagctcaacagagctgtccaggtcgtcgtgcacacgggtgacatcactgaggacctgctgttggacttccaggtggtggtgctgactgctgcaaagctggaggagcagctgaaggtgggcaccttgtgtcataagcatggagtttgctttctggcggctgacacccggggcctcgtggggcagttgttctgtgactttggtgaggacttcactgtgcaggaccccacagaggcagaacccctgacagctgccatccagcacatctcccagggctcccctggcattctcactctgaggaaaggggccaatacccactacttccgtgatggagacttggtgactttctcgggaattgagggaatggttgagctcaacgactgtgatccccggtctatccacgtgcgggaggatgggtccctggagattggagacacaacaactttctctcggtacttgcgtggtggggctatcactgaagtcaagagacccaagactgtgagacataagtccctggacacagccctgctccagccccatgtggtggcccagagctcccaggaagttcaccatgcccactgcctgcatcaggccttctgtgcactgcacaagttccagcacctccatggccggccaccccagccctgggatcctgttgatgcagagactgtggtgggcctggcccgggacctggaaccactgaagcggacagaggaagagccactggaagagccactggatgaggccctagtgcggacagtcgccctaagcagtgcaggtgtcttgagccctatggtggccatgctgggtgcagtagctgcccaggaagtgctgaaggcaatctccaggaagttcatgcctctggaccagtggctttactttgatgccctcgattgtcttccggaagatggggagctccttcccagtcctgaggactgtgccctgagaggcagccgctatgatgggcaaattgcagtgtttggggctggttttcaggagaaactgagacgccagcactacctcctggtgggcgctggtgccattggttgtgagctgctcaaagtctttgccctagtgggactgggggccgggaacagcgggggcttgactgttgttgacatggaccacatagagcgctccaatctcagccgtcagttcctcttcaggtcccaggacgttggtagacccaaggcagaggtggctgcagcagctgcccggggcctgaacccagacttacaggtgatcccgctcacctacccactggatcccaccacagagcacatctatggggataactttttctcccgtgtggatggtgtggctgctgccctggacagtttccaggcccggcgctatgtggctgctcgttgcacccactatctgaagccactgctggaggcaggcacatcgggcacctggggcagtgctacagtattcatgccacatgtgactgaggcctacagagcccctgcctcagctgcagcttctgaggatgccccctaccctgtctgtaccgtgcggtacttccctagcacagccgagcacaccctgcagtgggcccggcatgagtttgaagaactcttccgactgtctgcagagaccatcaaccaccaccaacaggcacacacttccctggcagacatggatgagccacagacactcaccttactgaagccagtgcttggggtcctgagagtgcgtccacagaactggcaagactgtgtggcgtgggctcttggccactggaaactctgctttcattatggcatcaaacagctgctgaggcacttcccacctaataaagtgcttgaggatggaactcccttctggtcaggtcccaaacagtgtccccagcccttggagtttgacaccaaccaagacacacacctcctctacgtactggcagctgccaacctgtatgcccagatgcatgggctgcctggctcacaggactggactgcactcagggagctgctgaagctgctgccacagcctgacccccaacagatggcccccatctttgctagtaatctagagctggcttcggcttctgctgagtttggccctgagcagcagaaggaactgaacaaagccctggaagtctggagtgtgggccctcccctgaagcctctgatgtttgagaaggatgatgacagcaacttccatgtggactttgtggtagcggcagctagcctgagatgtcagaactacgggattccaccggtcaaccgtgcccagagcaagcgaattgtgggccagattatcccagccattgccaccactacagcagctgtggcaggcctgttgggcctggagctgtataaggtggtgagtgggccacggcctcgtagtgcctttcgccacagctacctacatctggctgaaaactacctcatccgctatatgccttttgccccagccatccagacgttccatcacctgaagtggacctcttgggaccgtctgaaggtaccagctgggcagcctgagaggaccctggagtcgctgctggctcatcttcaggagcagcacgggttgagggtgaggatcctgctgcacggctcagccctgctctatgcggccggatggtcacctgaaaagcaggcccagcacctgcccctcagggtgacagaactggttcagcagctgacaggccaggcacctgctcctgggcagcgggtgttggtgctagagctgagctgtgagggtgacgacgaggacactgccttcccacctctgcactatgagctgtga
Sequence Length
3039
Vector
pUC
Clone Sequence Report
Provided with product shipment
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
111,694 Da
NCBI Official Full Name
Homo sapiens ubiquitin-like modifier activating enzyme 7, mRNA
NCBI Official Synonym Full Names
ubiquitin like modifier activating enzyme 7
NCBI Official Symbol
UBA7
NCBI Official Synonym Symbols
D8; UBE2; UBA1B; UBE1L
NCBI Protein Information
ubiquitin-like modifier-activating enzyme 7
UniProt Protein Name
Ubiquitin-like modifier-activating enzyme 7
Protein Family
UniProt Gene Name
UBA7
UniProt Synonym Gene Names
UBE1L; UBE2; Ubiquitin-activating enzyme 7
UniProt Entry Name
UBA7_HUMAN
NCBI Description
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq, Jul 2008]
Uniprot Description
UBE1L: Activates ubiquitin by first adenylating with ATP its C- terminal glycine residue and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin- E1 thioester and free AMP. Belongs to the ubiquitin-activating E1 family.
Protein type: EC 6.3.2.19; Ubiquitin conjugating system; Ubiquitin ligase
Chromosomal Location of Human Ortholog: 3p21
Cellular Component: cytosol; nucleoplasm; nucleus
Molecular Function: ISG15 activating enzyme activity; protein binding; ubiquitin activating enzyme activity; ubiquitin-protein ligase activity
Biological Process: bypass DNA synthesis; ISG15-protein conjugation; modification-dependent protein catabolic process; negative regulation of interferon type I production; protein modification process
Research Articles on UBA7
Similar Products
Product Notes
The UBA7 uba7 (Catalog #AAA1270151) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggatgccc tggacgcttc gaagctactg gatgaggagc tgtattcaag acagctgtat gtgctgggct cacctgccat gcagaggatt cagggagcca gggtcctggt gtcaggcctg cagggcctgg gggccgaggt ggccaagaac ttggttctga tgggtgtggg cagcctcact ctgcatgatc cccaccccac ctgctggtcc gacctggctg cccagtttct cctctcagag caggacttgg aaaggagcag agccgaggcc tctcaagagc tcttggctca gctcaacaga gctgtccagg tcgtcgtgca cacgggtgac atcactgagg acctgctgtt ggacttccag gtggtggtgc tgactgctgc aaagctggag gagcagctga aggtgggcac cttgtgtcat aagcatggag tttgctttct ggcggctgac acccggggcc tcgtggggca gttgttctgt gactttggtg aggacttcac tgtgcaggac cccacagagg cagaacccct gacagctgcc atccagcaca tctcccaggg ctcccctggc attctcactc tgaggaaagg ggccaatacc cactacttcc gtgatggaga cttggtgact ttctcgggaa ttgagggaat ggttgagctc aacgactgtg atccccggtc tatccacgtg cgggaggatg ggtccctgga gattggagac acaacaactt tctctcggta cttgcgtggt ggggctatca ctgaagtcaa gagacccaag actgtgagac ataagtccct ggacacagcc ctgctccagc cccatgtggt ggcccagagc tcccaggaag ttcaccatgc ccactgcctg catcaggcct tctgtgcact gcacaagttc cagcacctcc atggccggcc accccagccc tgggatcctg ttgatgcaga gactgtggtg ggcctggccc gggacctgga accactgaag cggacagagg aagagccact ggaagagcca ctggatgagg ccctagtgcg gacagtcgcc ctaagcagtg caggtgtctt gagccctatg gtggccatgc tgggtgcagt agctgcccag gaagtgctga aggcaatctc caggaagttc atgcctctgg accagtggct ttactttgat gccctcgatt gtcttccgga agatggggag ctccttccca gtcctgagga ctgtgccctg agaggcagcc gctatgatgg gcaaattgca gtgtttgggg ctggttttca ggagaaactg agacgccagc actacctcct ggtgggcgct ggtgccattg gttgtgagct gctcaaagtc tttgccctag tgggactggg ggccgggaac agcgggggct tgactgttgt tgacatggac cacatagagc gctccaatct cagccgtcag ttcctcttca ggtcccagga cgttggtaga cccaaggcag aggtggctgc agcagctgcc cggggcctga acccagactt acaggtgatc ccgctcacct acccactgga tcccaccaca gagcacatct atggggataa ctttttctcc cgtgtggatg gtgtggctgc tgccctggac agtttccagg cccggcgcta tgtggctgct cgttgcaccc actatctgaa gccactgctg gaggcaggca catcgggcac ctggggcagt gctacagtat tcatgccaca tgtgactgag gcctacagag cccctgcctc agctgcagct tctgaggatg ccccctaccc tgtctgtacc gtgcggtact tccctagcac agccgagcac accctgcagt gggcccggca tgagtttgaa gaactcttcc gactgtctgc agagaccatc aaccaccacc aacaggcaca cacttccctg gcagacatgg atgagccaca gacactcacc ttactgaagc cagtgcttgg ggtcctgaga gtgcgtccac agaactggca agactgtgtg gcgtgggctc ttggccactg gaaactctgc tttcattatg gcatcaaaca gctgctgagg cacttcccac ctaataaagt gcttgaggat ggaactccct tctggtcagg tcccaaacag tgtccccagc ccttggagtt tgacaccaac caagacacac acctcctcta cgtactggca gctgccaacc tgtatgccca gatgcatggg ctgcctggct cacaggactg gactgcactc agggagctgc tgaagctgct gccacagcct gacccccaac agatggcccc catctttgct agtaatctag agctggcttc ggcttctgct gagtttggcc ctgagcagca gaaggaactg aacaaagccc tggaagtctg gagtgtgggc cctcccctga agcctctgat gtttgagaag gatgatgaca gcaacttcca tgtggacttt gtggtagcgg cagctagcct gagatgtcag aactacggga ttccaccggt caaccgtgcc cagagcaagc gaattgtggg ccagattatc ccagccattg ccaccactac agcagctgtg gcaggcctgt tgggcctgga gctgtataag gtggtgagtg ggccacggcc tcgtagtgcc tttcgccaca gctacctaca tctggctgaa aactacctca tccgctatat gccttttgcc ccagccatcc agacgttcca tcacctgaag tggacctctt gggaccgtct gaaggtacca gctgggcagc ctgagaggac cctggagtcg ctgctggctc atcttcagga gcagcacggg ttgagggtga ggatcctgct gcacggctca gccctgctct atgcggccgg atggtcacct gaaaagcagg cccagcacct gcccctcagg gtgacagaac tggttcagca gctgacaggc caggcacctg ctcctgggca gcgggtgttg gtgctagagc tgagctgtga gggtgacgac gaggacactg ccttcccacc tctgcactat gagctgtga. It is sometimes possible for the material contained within the vial of "UBA7, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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