TNFRSF14 cdna clone
TNFRSF14 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. [provided by RefSeq, Jul 2008]
Uniprot Description
TNFRSF14: Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.
Protein type: Membrane protein, integral; Receptor, misc.; Cell cycle regulation
Chromosomal Location of Human Ortholog: 1p36.32
Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane
Molecular Function: viral receptor activity; protein binding; tumor necrosis factor receptor activity; ubiquitin protein ligase binding
Biological Process: positive regulation of peptidyl-tyrosine phosphorylation; entry of virus into host cell; defense response to Gram-positive bacterium; cell surface receptor linked signal transduction; tumor necrosis factor-mediated signaling pathway; T cell costimulation; positive regulation of cytokine secretion during immune response; negative regulation of alpha-beta T cell proliferation; immune response; defense response to Gram-negative bacterium
Research Articles on TNFRSF14
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Product Notes
The TNFRSF14 tnfrsf14 (Catalog #AAA1266815) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggagcctc ctggagactg ggggcctcct ccctggagat ccacccccag aaccgacgtc ttgaggctgg tgctgtatct caccttcctg ggagccccct gctacgcccc agctctgccg tcctgcaagg aggacgagta cccagtgggc tccgagtgct gccccaagtg cagtccaggt tatcgtgtga aggaggcctg cggggagctg acgggcacag tgtgtgaacc ctgccctcca ggcacctaca ttgcccacct caatggccta agcaagtgtc tgcagtgcca aatgtgtgac ccagccatgg gcctgcgcgc gagccggaac tgctccagga cagagaacgc cgtgtgtggc tgcagcccag gccacttctg catcgtccag gacggggacc actgcgccgc gtgccgcgct tacgccacct ccagcccggg ccagagggtg cagaagggag gcaccgagag tcaggacacc ctgtgtcaga actgcccccc ggggaccttc tctcccaatg ggaccctgga ggaatgtcag caccagacca agtgcagctg gctggtgacg aaggccggag ctgggaccag cagctcccac tgggtatggt ggtttctctc agggagcctc gtcatcgtca ttgtttgctc cacagttggc ctaatcatat gtgtgaaaag aagaaagcca aggggtgatg tagtcaaggt gatcgtctcc gtccagcgga aaagacagga ggcagaaggt gaggccacag tcattgaggc cctgcaggcc cctccggacg tcaccacggt ggccgtggag gagacaatac cctcattcac ggggaggagc ccaaaccact ga. It is sometimes possible for the material contained within the vial of "TNFRSF14, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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