TIE1 cdna clone
TIE1 cDNA Clone
Gene Names
TIE1; TIE; JTK14
Synonyms
TIE1; TIE1 cDNA Clone; TIE1 cdna clone
Sequence
atggtctggcgggtgccccctttcttgctccccatcctcttcttggcttctcatgtgggcgcggcggtggacctgacgctgctggccaacctgcggctcacggacccccagcgcttcttcctgacttgcgtgtctggggaggccggggcggggaggggctcggacgcctggggcccgcccctgctgctggagaaggacgaccgtatcgtgcgcaccccgcccgggccacccctgcgcctggcgcgcaacggttcgcaccaggtcacgcttcgcggcttctccaagccctcggacctcgtgggcgtcttctcctgcgtgggcggtgctggggcgcggcgcacgcgcgtcatctacgtgcacaacagccctggagcccacctgcttccagacaaggtcacacacactgtgaacaaaggtgacaccgctgtactttctgcacgtgtgcacaaggagaagcagacagacgtgatctggaagagcaacggatcctacttctacaccctggactggcatgaagcccaggatgggcggttcctgctgcagctcccaaatgtgcagccaccatcgagcggcatctacagtgccacttacctggaagccagccccctgggcagcgccttctttcggctcatcgtgcggggttgtggggctgggcgctgggggccaggctgtaccaaggagtgcccaggttgcctacatggaggtgtctgccacgaccatgacggcgaatgtgtatgcccccctggcttcactggcacccgctgtgaacaggcctgcagagagggccgttttgggcagagctgccaggagcagtgcccaggcatatcaggctgccggggcctcaccttctgcctcccagacccctatggctgctcttgtggatctggctggagaggaagccagtgccaagaagcttgtgcccctggtcattttggggctgattgccgactccagtgccagtgtcagaatggtggcacttgtgaccggttcagtggttgtgtctgcccctctgggtggcatggagtgcactgtgagaagtcagaccggatcccccagatcctcaacatggcctcagaactggagttcaacttagagacgatgccccggatcaactgtgcagctgcagggaaccccttccccgtgcggggcagcatagagctacgcaagccagacggcactgtgctcctgtccaccaaggccattgtggagccagagaagaccacagctgagttcgaggtgccccgcttggttcttgcggacagtgggttctgggagtgccgtgtgtccacatctggcggccaagacagccggcgcttcaaggtcaatgtgaaagtgccccccgtgcccctggctgcacctcggctcctgaccaagcagagccgccagcttgtggtctccccgctggtctcgttctctggggatggacccatctccactgtccgcctgcactaccggccccaggacagtaccatggactggtcgaccattgtggtggaccccagtgagaacgtgacgttaatgaacctgaggccaaagacaggatacagtgttcgtgtgcagctgagccggccaggggaaggaggagagggggcctgggggcctcccaccctcatgaccacagactgtcctgagcctttgttgcagccgtggttggagggctggcatgtggaaggcactgaccggctgcgagtgagctggtccttgcccttggtgcccgggccactggtgggcgacggtttcctgctgcgcctgtgggacgggacacgggggcaggagcggcgggagaacgtctcatccccccaggcccgcactgccctcctgacgggactcacgcctggcacccactaccagctggatgtgcagctctaccactgcaccctcctgggcccggcctcgccccctgcacacgtgcttctgccccccagtgggcctccagccccccgacacctccacgcccaggccctctcagactccgagatccagctgacatggaagcacccggaggctctgcctgggccaatatccaagtacgttgtggaggtgcaggtggctgggggtgcaggagacccactgtggatagacgtggacaggcctgaggagacaagcaccatcatccgtggcctcaacgccagcacgcgctacctcttccgcatgcgggccagcattcaggggctcggggactggagcaacacagtagaagagtccaccctgggcaacgggctgcaggctgagggcccagtccaagagagccgggcagctgaagagggcctggatcagcagctgatcctggcggtggtgggctccgtgtctgccacctgcctcaccatcctggccgcccttttaaccctggtgtgcatccgcagaagctgcctgcatcggagacgcaccttcacctaccagtcaggctcgggcgaggagaccatcctgcagttcagctcagggaccttgacacttacccggcggccaaaactgcagcccgagcccctgagctacccagtgctagagtgggaggacatcacctttgaggacctcatcggggaggggaacttcggccaggtcatccgggccatgatcaagaaggacgggctgaagatgaacgcagccatcaaaatgctgaaagagtatgcctctgaaaatgaccatcgtgactttgcgggagaactggaagttctgtgcaaattggggcatcaccccaacatcatcaacctcctgggggcctgtaagaaccgaggttacttgtatatcgctattgaatatgccccctacgggaacctgctagattttctgcggaaaagccgggtcctagagactgacccagcttttgctcgagagcatgggacagcctctacccttagctcccggcagctgctgcgtttcgccagtgatgcggccaatggcatgcagtacctgagtgagaagcagttcatccacagggacctggctgcccggaatgtgctggtcggagagaacctagcctccaagattgcagacttcggcctttctcggggagaggaggtttatgtgaagaagacgatggggcgtctccctgtgcgctggatggccattgagtccctgaactacagtgtctataccaccaagagtgatgtctggtcctttggagtccttctttgggagatagtgagccttggaggtacaccctactgtggcatgacctgtgccgagctctatgaaaagctgccccagggctaccgcatggagcagcctcgaaactgtgacgatgaagtgtacgagctgatgcgtcagtgctggcgggaccgtccctatgagcgacccccctttgcccagattgcgctacagctaggccgcatgctggaagccaggaaggcctatgtgaacatgtcgctgtttgagaacttcacttacgcgggcattgatgccacagctgaggaggcctga
Sequence Length
3417
Vector
pUC
Clone Sequence Report
Provided with product shipment
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
34,138 Da
NCBI Official Full Name
Homo sapiens tyrosine kinase with immunoglobulin-like and EGF-like domains 1, mRNA
NCBI Official Synonym Full Names
tyrosine kinase with immunoglobulin like and EGF like domains 1
NCBI Official Symbol
TIE1
NCBI Official Synonym Symbols
TIE; JTK14
NCBI Protein Information
tyrosine-protein kinase receptor Tie-1
UniProt Protein Name
Tyrosine-protein kinase receptor Tie-1
Protein Family
UniProt Gene Name
TIE1
UniProt Synonym Gene Names
TIE
UniProt Entry Name
TIE1_HUMAN
NCBI Description
This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Uniprot Description
TIE1: Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis. Belongs to the protein kinase superfamily. Tyr protein kinase family. Tie subfamily.
Protein type: Protein kinase, tyrosine (receptor); Membrane protein, integral; Protein kinase, TK; Kinase, protein; EC 2.7.10.1; TK group; Tie family
Chromosomal Location of Human Ortholog: 1p34-p33
Cellular Component: integral to plasma membrane
Molecular Function: protein binding
Biological Process: mesoderm development; signal transduction
Research Articles on TIE1
Similar Products
Product Notes
The TIE1 tie1 (Catalog #AAA1266568) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggtctggc gggtgccccc tttcttgctc cccatcctct tcttggcttc tcatgtgggc gcggcggtgg acctgacgct gctggccaac ctgcggctca cggaccccca gcgcttcttc ctgacttgcg tgtctgggga ggccggggcg gggaggggct cggacgcctg gggcccgccc ctgctgctgg agaaggacga ccgtatcgtg cgcaccccgc ccgggccacc cctgcgcctg gcgcgcaacg gttcgcacca ggtcacgctt cgcggcttct ccaagccctc ggacctcgtg ggcgtcttct cctgcgtggg cggtgctggg gcgcggcgca cgcgcgtcat ctacgtgcac aacagccctg gagcccacct gcttccagac aaggtcacac acactgtgaa caaaggtgac accgctgtac tttctgcacg tgtgcacaag gagaagcaga cagacgtgat ctggaagagc aacggatcct acttctacac cctggactgg catgaagccc aggatgggcg gttcctgctg cagctcccaa atgtgcagcc accatcgagc ggcatctaca gtgccactta cctggaagcc agccccctgg gcagcgcctt ctttcggctc atcgtgcggg gttgtggggc tgggcgctgg gggccaggct gtaccaagga gtgcccaggt tgcctacatg gaggtgtctg ccacgaccat gacggcgaat gtgtatgccc ccctggcttc actggcaccc gctgtgaaca ggcctgcaga gagggccgtt ttgggcagag ctgccaggag cagtgcccag gcatatcagg ctgccggggc ctcaccttct gcctcccaga cccctatggc tgctcttgtg gatctggctg gagaggaagc cagtgccaag aagcttgtgc ccctggtcat tttggggctg attgccgact ccagtgccag tgtcagaatg gtggcacttg tgaccggttc agtggttgtg tctgcccctc tgggtggcat ggagtgcact gtgagaagtc agaccggatc ccccagatcc tcaacatggc ctcagaactg gagttcaact tagagacgat gccccggatc aactgtgcag ctgcagggaa ccccttcccc gtgcggggca gcatagagct acgcaagcca gacggcactg tgctcctgtc caccaaggcc attgtggagc cagagaagac cacagctgag ttcgaggtgc cccgcttggt tcttgcggac agtgggttct gggagtgccg tgtgtccaca tctggcggcc aagacagccg gcgcttcaag gtcaatgtga aagtgccccc cgtgcccctg gctgcacctc ggctcctgac caagcagagc cgccagcttg tggtctcccc gctggtctcg ttctctgggg atggacccat ctccactgtc cgcctgcact accggcccca ggacagtacc atggactggt cgaccattgt ggtggacccc agtgagaacg tgacgttaat gaacctgagg ccaaagacag gatacagtgt tcgtgtgcag ctgagccggc caggggaagg aggagagggg gcctgggggc ctcccaccct catgaccaca gactgtcctg agcctttgtt gcagccgtgg ttggagggct ggcatgtgga aggcactgac cggctgcgag tgagctggtc cttgcccttg gtgcccgggc cactggtggg cgacggtttc ctgctgcgcc tgtgggacgg gacacggggg caggagcggc gggagaacgt ctcatccccc caggcccgca ctgccctcct gacgggactc acgcctggca cccactacca gctggatgtg cagctctacc actgcaccct cctgggcccg gcctcgcccc ctgcacacgt gcttctgccc cccagtgggc ctccagcccc ccgacacctc cacgcccagg ccctctcaga ctccgagatc cagctgacat ggaagcaccc ggaggctctg cctgggccaa tatccaagta cgttgtggag gtgcaggtgg ctgggggtgc aggagaccca ctgtggatag acgtggacag gcctgaggag acaagcacca tcatccgtgg cctcaacgcc agcacgcgct acctcttccg catgcgggcc agcattcagg ggctcgggga ctggagcaac acagtagaag agtccaccct gggcaacggg ctgcaggctg agggcccagt ccaagagagc cgggcagctg aagagggcct ggatcagcag ctgatcctgg cggtggtggg ctccgtgtct gccacctgcc tcaccatcct ggccgccctt ttaaccctgg tgtgcatccg cagaagctgc ctgcatcgga gacgcacctt cacctaccag tcaggctcgg gcgaggagac catcctgcag ttcagctcag ggaccttgac acttacccgg cggccaaaac tgcagcccga gcccctgagc tacccagtgc tagagtggga ggacatcacc tttgaggacc tcatcgggga ggggaacttc ggccaggtca tccgggccat gatcaagaag gacgggctga agatgaacgc agccatcaaa atgctgaaag agtatgcctc tgaaaatgac catcgtgact ttgcgggaga actggaagtt ctgtgcaaat tggggcatca ccccaacatc atcaacctcc tgggggcctg taagaaccga ggttacttgt atatcgctat tgaatatgcc ccctacggga acctgctaga ttttctgcgg aaaagccggg tcctagagac tgacccagct tttgctcgag agcatgggac agcctctacc cttagctccc ggcagctgct gcgtttcgcc agtgatgcgg ccaatggcat gcagtacctg agtgagaagc agttcatcca cagggacctg gctgcccgga atgtgctggt cggagagaac ctagcctcca agattgcaga cttcggcctt tctcggggag aggaggttta tgtgaagaag acgatggggc gtctccctgt gcgctggatg gccattgagt ccctgaacta cagtgtctat accaccaaga gtgatgtctg gtcctttgga gtccttcttt gggagatagt gagccttgga ggtacaccct actgtggcat gacctgtgcc gagctctatg aaaagctgcc ccagggctac cgcatggagc agcctcgaaa ctgtgacgat gaagtgtacg agctgatgcg tcagtgctgg cgggaccgtc cctatgagcg accccccttt gcccagattg cgctacagct aggccgcatg ctggaagcca ggaaggccta tgtgaacatg tcgctgtttg agaacttcac ttacgcgggc attgatgcca cagctgagga ggcctga. It is sometimes possible for the material contained within the vial of "TIE1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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