SYT5 cdna clone
SYT5 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 [PubMed 7597049]).[supplied by OMIM, Feb 2011]
Uniprot Description
SYT5: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)- dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface. Belongs to the synaptotagmin family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 19q13.42|11p
Cellular Component: plasma membrane; synaptic vesicle membrane
Molecular Function: calcium ion binding; calcium-dependent phospholipid binding; clathrin binding; syntaxin binding
Biological Process: calcium ion-dependent exocytosis of neurotransmitter; regulation of calcium ion-dependent exocytosis; synaptic transmission; synaptic vesicle endocytosis; vesicle fusion
Research Articles on SYT5
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Product Notes
The SYT5 syt5 (Catalog #AAA1272479) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgttcccgg agcccccaac cccggggcct ccatcgcccg acacgcctcc cgactccagt cgcatcagcc acggcccagt gcccccctgg gccctggcca ccatcgtgct ggtctcaggc ctcctcatct tcagctgctg tttctgtctc taccggaaga gctgtcggag gcggacaggc aagaagagcc aggcccaagc ccaggtccac cttcaggaag tgaaggggct gggccagagt tacatagaca aggtgcagcc agaagtagag gagctggagc cagcaccatc cgggccaggg cagcaggtgg cagacaagca tgagctagga caactgcagt actccctgga ttatgacttc cagagtggcc agctgctggt gggcattctg caagcaatgg gattggcagc cttggatctt ggtggctcct cggaccccta tgtgcgggtc tacctgctgc cggacaaacg gaggcggtac gagaccaagg tgcatcggca gacgctgaac cctcactttg gggagacctt cgccttcaag gtcccctacg tggagctggg gggcagggtg ctggtcatgg cggtgtacga cttcgaccgc ttctctcgca atgacgccat cggggaggtg cgggtcccta tgagctccgt ggacctgggg cggccagtgc aggcctggcg ggagctgcag gcggctccgc gggaggagca ggagaagctt ggggacatct gcttctccct ccgctatgtc cccacggccg ggaagctcac cgtcatcgtc ctggaggcta aaaacctgaa gaagatggac gtaggaggac tgtcagatcc atacgtcaag gtccacctgc tgcagggcgg caaaaaggtg cggaagaaga aaaccaccat caagaagaac actctgaacc cctattacaa cgaagctttc agcttcgagg tgccctgtga ccaagtccag aaggtgcagg tggagctgac cgtgctggac tacgacaagc tgggcaagaa cgaggccatc gggagggtgg ccgtgggggc ggccgccggc ggggctggcc tgcggcactg ggcggacatg ctggccaacc cgcggcggcc cattgcccag tggcactcgc tgcggccccc ggaccgagtg aggctgctgc ctgcgccctg a. It is sometimes possible for the material contained within the vial of "SYT5, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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