SRD5A1 cdna clone
SRD5A1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).[supplied by OMIM, Mar 2008]
Uniprot Description
SRD5A1: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5- alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. Belongs to the steroid 5-alpha reductase family.
Protein type: Membrane protein, multi-pass; Lipid Metabolism - androgen and estrogen; Oxidoreductase; Membrane protein, integral; EC 1.3.1.22
Chromosomal Location of Human Ortholog: 5p15
Cellular Component: endoplasmic reticulum membrane
Molecular Function: 3-oxo-5-alpha-steroid 4-dehydrogenase activity; electron carrier activity
Biological Process: androgen biosynthetic process
Research Articles on SRD5A1
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Product Notes
The SRD5A1 srd5a1 (Catalog #AAA1268135) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggcaacgg cgacgggggt ggcggaggag cgcctgctgg ccgcgctcgc ctacctgcag tgcgccgtgg gctgcgcggt cttcgcgcgg aatcgtcaga cgaactcagt gtacggccgc cacgcgctgc ccagccacag gctccgagtg ccggcgcggg ccgcctgggt ggtgcaggag ctgccctcgc tggccctgcc gctctaccag tacgccagcg agtccgcccc gcgtctccgc agcgcgccca actgcatcct cctggccatg ttcctcgtcc actacgggca tcggtgctta atttacccat ttctgatgcg aggaggaaag cctatgccac tgttggcgtg tacaatggcg attatgttct gtacctgtaa cggctatttg caaagcagat acttgagcca ttgtgcagtg tatgctgatg actgggtaac agatccccgt tttctaatag gttttggctt gtggttaacg ggcatgttga taaacatcca ttcagatcat atcctaagga atctcagaaa accaggagat actggataca aaataccaag gggaggctta tttgaatacg taactgcagc caactatttt ggagaaatca tggagtggtg tggctatgcc ctggccagct ggtctgtcca aggcgcggct tttgctttct tcacgttttg ttttttatct ggtagagcaa aagagcatca tgagtggtac ctccggaaat ttgaagagta tccaaagttc agaaaaatta taattccatt tttgttttaa. It is sometimes possible for the material contained within the vial of "SRD5A1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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