SPIRE2 cdna clone

SPIRE2 cDNA Clone

Gene Names

SPIRE2; Spir-2

Synonyms

SPIRE2; SPIRE2 cDNA Clone; SPIRE2 cdna clone

Ordering
Cat. Num. AAA1275840 For Research Use Only!

Sequence

ATGGCCAACAACGACAGCGAGGACAGCGGCTGCGGTGCCGCCGATGAGGGCTACGGGGGTCCCGAGGAGGAGGAGGAGGCCGAGGGCGTCCCCCGCAGCGTGCGCACCTTTGCCCAGGCCATGCGGCTGTGCGCGGCGCGGCTGACCGACCCCCGGGGCGCACAGGCGCATTACCAGGCCGTGTGCCGCGCGCTCTTCGTGGAGACGCTGGAGCTGCGGGCCTTCCTGGCCAGGGTCCGGGAGGCCAAGGAGATGCTGCAGAAGCTTCGGGAGGACGAGCCGCATCTGGAGACGCCTCGGGCAGAGCTGGACAGCCTGGGTCACACAGACTGGGCCCGACTGTGGGTTCAGCTCATGCGGGAGCTCCGCCGCGGAGTGAAGCTGAAGAAGGTGCAAGAGCAGGAGTTCAACCCCCTCCCCACCGAGTTCCAGCTCACGCCCTTCGAGATGCTGATGCAGGACATCCGGGCCCGGAACTACAAGCTGCGCAAGGTGGATGGGGACATCCCGCCCCGGGTGAAGAAGGACGCTCACGAGCTCATCCTGGACTTTATCCGCTCACGGCCTCCACTGAAGCAGGTCTCTGAGAGGCGGCTGCGCCCGTTGCCACCAAAGCAAAGGTCCCTGCATGAGAAGATCCTGGAGGAGATCAAGCAGGAGCGGAGGCTGCGCCCGGTGCGGGGCGAGGGCTGGGCTGCCCGCGGGTTTGGCTCTCTGCCCTGCATCCTCAACGCCTGCTCCGGAGATGCCAAGTCCACCTCCTGCATCAACCTGTCAGTCACAGATGCTGGGGGCAGCGCCCAGCGCCCGCGGCCCCGCGTGCTGCTCAAGGCGCCTACCTTGGCTGAAATGGAAGAGATGAATACATCTGAGGAAGAAGAGTCTCCGTGTGGGGAGGTGACGCTGAAACGGGACCGCTCCTTCTCAGAGCATGACCTGGCCCAGCTCCGAAGTGAGGTGGCCTCTGGCCTGCAGTCGGCCACCCACCCCCCAGGAGGGACGGAGCCACCACGGCCCCGAGCTGGCAGTGCGCATGTGTGGAGGCCCGGCTCCCGAGACCAGGGTACCTGTCCCGCGAGTGTCTCTGACCCCAGCCACCCCCTACTCAGCAACCGGGGCTCCTCGGGGGACAGACCCGAGGCCTCCATGACCCCCGATGCCAAACACCTGTGGCTGGAGTTCAGCCACCCCGTGGAGAGCCTGGCGCTGACTGTGGAAGAGGTGATGGACGTGCGCCGTGTGCTGGTGAAGGCCGAGATGGAAAAGTTTTTGCAGAACAAGGAGCTCTTCAGCAGTCTGAAGAAGGGGAAGATTTGCTGCTGCTGCCGGGCCAAGTTCCCGCTGTTCTCGTGGCCGCCCAGCTGTCTCTTCTGCAAGAGAGCCGTCTGCACTTCCTGTAGCATAAAGATGAAGATGCCTTCTAAGAAATTTGGACACATCCCTGTCTACACACTGGGCTTTGAGAGTCCTCAGAGGGTATCAGCTGCCAAAACCGCGCCAATCCAGAGAAGAGACATCTTTCAGTCTCTGCAAGGGCCACAGTGGCAGAGCGTGGAGGAGGCGTTCCCCCACATCTACTCCCACGGCTGTGTCCTGAAGGATGTCTGCAGTGAGTGCACCAGCTTTGTGGCAGACGTGGTGCGTTCCAGCCGCAAGAGCGTGGACGTCCTCAACACTACGCCACGACGCAGTCGCCAGACCCAATCCCTCTACATCCCTAACACCAGGACTTTTGACTTCAAGTGA

Sequence Length

1746

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

NCBI and Uniprot Product Information

NCBI GI #

141796931

NCBI GeneID

84501

Molecular Weight

65,375 Da

NCBI Official Full Name

Homo sapiens spire homolog 2 (Drosophila), mRNA

NCBI Official Synonym Full Names

spire type actin nucleation factor 2

NCBI Official Symbol

SPIRE2

NCBI Official Synonym Symbols

Spir-2

NCBI Protein Information

protein spire homolog 2

UniProt Protein Name

Protein spire homolog 2

Protein Family

Protein spire

UniProt Gene Name

SPIRE2

UniProt Synonym Gene Names

KIAA1832; SPIR2; Spir-2

UniProt Entry Name

SPIR2_HUMAN

Uniprot Description

SPIRE2: Acts as a actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in vesicle transport processes providing a novel link between actin organization and intracellular transport. Belongs to the spire family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 16q24

Cellular Component: cell cortex; cleavage furrow; cytoplasmic vesicle membrane

Biological Process: actin cytoskeleton organization and biogenesis; establishment of meiotic spindle localization; intracellular transport; polar body extrusion after meiotic divisions; vesicle-mediated transport

Research Articles on SPIRE2

1. This DNA damage-induced nuclear actin assembly requires two biologically and physically linked nucleation factors: Formin-2 and Spire-1/Spire-2.

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Product Notes

The SPIRE2 spire2 (Catalog #AAA1275840) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGCCAACA ACGACAGCGA GGACAGCGGC TGCGGTGCCG CCGATGAGGG CTACGGGGGT CCCGAGGAGG AGGAGGAGGC CGAGGGCGTC CCCCGCAGCG TGCGCACCTT TGCCCAGGCC ATGCGGCTGT GCGCGGCGCG GCTGACCGAC CCCCGGGGCG CACAGGCGCA TTACCAGGCC GTGTGCCGCG CGCTCTTCGT GGAGACGCTG GAGCTGCGGG CCTTCCTGGC CAGGGTCCGG GAGGCCAAGG AGATGCTGCA GAAGCTTCGG GAGGACGAGC CGCATCTGGA GACGCCTCGG GCAGAGCTGG ACAGCCTGGG TCACACAGAC TGGGCCCGAC TGTGGGTTCA GCTCATGCGG GAGCTCCGCC GCGGAGTGAA GCTGAAGAAG GTGCAAGAGC AGGAGTTCAA CCCCCTCCCC ACCGAGTTCC AGCTCACGCC CTTCGAGATG CTGATGCAGG ACATCCGGGC CCGGAACTAC AAGCTGCGCA AGGTGGATGG GGACATCCCG CCCCGGGTGA AGAAGGACGC TCACGAGCTC ATCCTGGACT TTATCCGCTC ACGGCCTCCA CTGAAGCAGG TCTCTGAGAG GCGGCTGCGC CCGTTGCCAC CAAAGCAAAG GTCCCTGCAT GAGAAGATCC TGGAGGAGAT CAAGCAGGAG CGGAGGCTGC GCCCGGTGCG GGGCGAGGGC TGGGCTGCCC GCGGGTTTGG CTCTCTGCCC TGCATCCTCA ACGCCTGCTC CGGAGATGCC AAGTCCACCT CCTGCATCAA CCTGTCAGTC ACAGATGCTG GGGGCAGCGC CCAGCGCCCG CGGCCCCGCG TGCTGCTCAA GGCGCCTACC TTGGCTGAAA TGGAAGAGAT GAATACATCT GAGGAAGAAG AGTCTCCGTG TGGGGAGGTG ACGCTGAAAC GGGACCGCTC CTTCTCAGAG CATGACCTGG CCCAGCTCCG AAGTGAGGTG GCCTCTGGCC TGCAGTCGGC CACCCACCCC CCAGGAGGGA CGGAGCCACC ACGGCCCCGA GCTGGCAGTG CGCATGTGTG GAGGCCCGGC TCCCGAGACC AGGGTACCTG TCCCGCGAGT GTCTCTGACC CCAGCCACCC CCTACTCAGC AACCGGGGCT CCTCGGGGGA CAGACCCGAG GCCTCCATGA CCCCCGATGC CAAACACCTG TGGCTGGAGT TCAGCCACCC CGTGGAGAGC CTGGCGCTGA CTGTGGAAGA GGTGATGGAC GTGCGCCGTG TGCTGGTGAA GGCCGAGATG GAAAAGTTTT TGCAGAACAA GGAGCTCTTC AGCAGTCTGA AGAAGGGGAA GATTTGCTGC TGCTGCCGGG CCAAGTTCCC GCTGTTCTCG TGGCCGCCCA GCTGTCTCTT CTGCAAGAGA GCCGTCTGCA CTTCCTGTAG CATAAAGATG AAGATGCCTT CTAAGAAATT TGGACACATC CCTGTCTACA CACTGGGCTT TGAGAGTCCT CAGAGGGTAT CAGCTGCCAA AACCGCGCCA ATCCAGAGAA GAGACATCTT TCAGTCTCTG CAAGGGCCAC AGTGGCAGAG CGTGGAGGAG GCGTTCCCCC ACATCTACTC CCACGGCTGT GTCCTGAAGG ATGTCTGCAG TGAGTGCACC AGCTTTGTGG CAGACGTGGT GCGTTCCAGC CGCAAGAGCG TGGACGTCCT CAACACTACG CCACGACGCA GTCGCCAGAC CCAATCCCTC TACATCCCTA ACACCAGGAC TTTTGACTTC AAGTGA. It is sometimes possible for the material contained within the vial of "SPIRE2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

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SPIRE2 cdna clone