SPACA1 cdna clone
SPACA1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively. [provided by RefSeq, Jul 2008]
Uniprot Description
SPACA1: May be involved in sperm-egg fusion.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 6q15
Cellular Component: acrosomal membrane
Biological Process: acrosome formation
Research Articles on SPACA1
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Product Notes
The SPACA1 spaca1 (Catalog #AAA1276142) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgagcccca ggggcacggg ctgctccgcc gggctgctga tgactgtcgg ctggctgctt ctggcgggcc tccagtccgc gcgcgggacc aacgtcaccg ctgccgtcca ggatgccggc ctggcccacg aaggcgaggg cgaggaggag accgaaaaca acgacagcga gaccgcggag aactacgctc cgcctgaaac cgaggatgtt tcaaatagga atgtcgtcaa agaagtagaa ttcggaatgt gcaccgttac atgtggtatt ggtgttagag aagttatatt aacaaatgga tgccctggtg gtgaatccaa gtgtgttgta cgggtagaag aatgccgtgg accaacagat tgtggctggg gtaaaccaat ttcagaaagt cttgaaagtg ttagattggc atgtattcac acatctccct taaatcgttt caaatatatg tggaaacttc taagacaaga ccaacaatcc attatacttg taaatgattc agcaatccta gaagtacgca aggaaagtca ccccttggct ttcgagtgtg acacactgga taataatgaa atagtagcaa ctattaaatt cacagtctat acgagcagtg aattgcagat gagaagatca agcctaccag ccactgatgc agccctaatt tttgtgctga ccataggagt cattatctgt gtatttataa ttttcttatt gatcttcata atcataaatt gggcagcagt caaggctttc tggggggcaa aagcctctac acccgaggta caatccgagc agagttctgt gagatacaaa gattcaactt ctcttgacca attaccaaca gaaatgcctg gtgaagatga tgctttaagt gaatggaatg aatga. It is sometimes possible for the material contained within the vial of "SPACA1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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