SLC5A11 cdna clone
SLC5A11 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
Cotransporters, such as SLC5A11, represent a major class of proteins that make use of ion gradients to drive active transport for the cellular accumulation of nutrients, neurotransmitters, osmolytes, and ions Roll et al. (2002) [PubMed 12039040].[supplied by OMIM, Mar 2008]
Uniprot Description
SLC5A11: Involved in the sodium-dependent cotransport of myo- inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D- xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family; Transporter
Chromosomal Location of Human Ortholog: 16p12.1
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: polyol transmembrane transporter activity; protein binding; symporter activity
Research Articles on SLC5A11
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Product Notes
The SLC5A11 slc5a11 (Catalog #AAA1273234) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggtgtggt ggccagtggg tgcatccttg tttgccagca atgttggaag tggacatttc attggcctgg cagggtcagg tgctgctacg ggcatttctg tatcagctta tgaacttaat ggcttgtttt ctgtgctgat gttggcctgg atcttcctac ccatctacat tgctggtcag gtcaccacga tgccagaata cctacggaag cgcttcggtg gcatcagaat ccccatcatc ctggctgtac tctacctatt tatctacatc ttcaccaaga tctcggtaga catgtatgca ggtgccatct tcatccagca gtctttgcac ctggatctgt acctggccat agttgggcta ctggccatca ctgctgtata cacggttgct ggtggcctgg ctgctgtgat ctacacggat gccctgcaga cgctgatcat gcttatagga gcgctcacct tgatgggcta cagtttcgcc gcggttggtg ggatggaagg actgaaggag aagtacttct tggccctggc tagcaaccgg agtgagaaca gcagctgcgg gctgccccgg gaagatgcct tccatatttt ccgagatccg ctgacatctg atctcccgtg gccgggggtc ctatttggaa tgtccatccc atccctctgg tactggtgca cggatcaggt gattgtccag cggactctgg ctgccaagaa cctgtcccat gccaaaggag gtgctctgat ggctgcatac ctgaaggtgc tgcccctctt cataatggtg ttccctggga tggtcagccg catcctcttc ccagatcaag tggcctgtgc agatccagag atctgccaga agatctgcag caacccctca ggctgttcgg acattgcgta tcccaaactc gtgctggaac tcctgcccac agggctccgt gggctgatga tggctgtgat ggtggcggct ctcatgtcct ccctcacctc catctttaac agtgccagca ccatcttcac catggacctc tggaatcacc tccggcctcg ggcatctgag aaggagctca tgattgtggg cagggtgttt gtgctgctgc tggtcctggt ctccatcctc tggatccctg tggtccaggc cagccagggc ggccagctct tcatctatat ccggtccatc agctcctacc tgcagccgcc tgtggcggtg gtcttcatca tgggatgttt ctggaagagg accaatgaaa agggtgcctt ctggggcctg atctcgggcc tgctcctggg cttggttagg ctggtcctgg actttattta cgtgcagcct cgatgcgacc agccagatga gcgcccggtc ctggtgaaga gcattcacta cctctacttc tccatgatcc tgtccacggt caccctcatc actgtctcca ccgtgagctg gttcacagag ccaccctcca aggagatggt cagccacctg acctggttta ctcgtcacga ccccgtggtc cagaaggaac aagcaccacc agcagctccc ttgtctctta ccctctctca gaacgggatg ccagaggcca gcagcagcag cagcgtccag ttcgagatgg ttcaagaaaa cacgtctaaa acccacagct gtgacatgac cccaaagcag tccaaagtgg tgaaggccat cctgtggctc tgtggaatac aggagaaggg caaggaagag ctcccggcca gagcagaagc catcatagtt tccctggaag aaaacccctt ggtgaagacc ctcctggacg tcaacctcat tttctgcgtg agctgcgcca tctttatctg gggctatttt gcttag. It is sometimes possible for the material contained within the vial of "SLC5A11, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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