SLC24A5 cdna clone
SLC24A5 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the potassium-dependent sodium/calcium exchanger family and encodes an intracellular membrane protein with 2 large hydrophilic loops and 2 sets of multiple transmembrane-spanning segments. Sequence variation in this gene has been associated with differences in skin pigmentation. [provided by RefSeq, Jul 2008]
Uniprot Description
SLC24A5: Cation exchanger involved in pigmentation, possibly by participating in ion transport in melanosomes. Probably transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.
Protein type: Transporter, SLC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral
Chromosomal Location of Human Ortholog: 15q21.1
Cellular Component: integral to plasma membrane; trans-Golgi network; trans-Golgi network membrane
Molecular Function: calcium channel activity; calcium ion binding; calcium, potassium:sodium antiporter activity; potassium ion binding; sodium ion binding
Biological Process: cellular calcium ion homeostasis; ion transport
Disease: Skin/hair/eye Pigmentation, Variation In, 4
Research Articles on SLC24A5
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Product Notes
The SLC24A5 slc24a5 (Catalog #AAA1276781) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgcagacaa aagggggcca aacatgggcg agaagggctc tgttgctcgg catcctgtgg gccactgcac atctgcctct ctcagggacc tccctgcccc aacgtctccc aagggccaca ggaaatagca cccaatgtgt tatttctcca tcatcggagt ttcccgaagg gtttttcacg agacaggagc gcagagatgg aggcatcata atctatttcc taattatcgt ttacatgttc atggccatat ctattgtctg tgatgaatac ttcctaccct ccctggaaat catcagtgaa tcccttggat tgtctcagga tgttgcaggc acaactttca tggcagcggg cagttcagct cctgaattag ttactgcttt cctaggtgta tttatcacaa agggagatat tggcattagc accatccttg gatctgcaat ttataatctc cttggcatct gtgctgcctg tggtttgcta tctaatacgg tctcaacact atcatgttgg cccctattca gagactgtgc agcgtacaca attagtgcag cagcagttct tggtataata tatgacaacc aagtttactg gtatgaaggg gctttactgc ttttgatata tggattgtat gttttggtgc tgtgttttga cattaaaatt aaccaatata ttataaagaa atgcagtcct tgctgcgcct gtcttgccaa agctatggag agaagtgaac aacagccact gatgggctgg gaagatgaag gtcaaccatt cattcgtcgg caatcaagaa ctgatagtgg aatattttat gaagattctg gctactctca gctctctata agtttacatg gccttagtca ggtttctgaa gatccaccaa gtgttttcaa catgcctgaa gcagacttaa aaagaatttt ttgggtatta tcccttccta ttattacatt actttttcta accacaccag attgtagaaa aaagttttgg aaaaactact ttgtgataac ctttttcatg tctgcaatat ggatatccgc atttacatat atcctggttt ggatggtcac aataactggg gaaacactag aaattcccga tacagtaatg ggccttactt tattagcagc aggaacaagc ataccagaca caattgcaag tgtgttggtt gcaagaaaag ggaaaggaga tatggctatg tctaacatcg tgggatccaa tgtgtttgat atgttgtgcc ttggtattcc atggtttatt aaaactgcat ttataaatgg atcagctcct gcagaagtaa acagcagagg actaacttac ataaccatct ctctcaacat ttcaattatt tttctttttt tagcagttca cttcaatggc tggaaactag acagaaagtt gggaatagtc tgcctattat catacttggg gcttgctaca ttatcagttc tatatgaact tggaattatt ggaaataata aaataagggg ctgtggaggt tga. It is sometimes possible for the material contained within the vial of "SLC24A5, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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