SHPRH cdna clone
SHPRH cDNA Clone
Gene Names
SHPRH; bA545I5.2
Synonyms
SHPRH; SHPRH cDNA Clone; SHPRH cdna clone
Sequence
ATGAGCAGCCGACGGAAACGTGCTCCTCCAGTGAGGGTAGATGAGGAAAAGAGGCAGCAGCTTCATTGGAATATGCATGAGGACAGAAGGAATGAACCTATCATCATAAGTGATGATGACGAGCAGCCCTGCCCAGGTTCAGATACCTCTTCTGCTCATTATATCATTCTAAGTGATAGTCTAAAGGAAGAAGTGGCTCACAGAGATAAGAAGAGGTGTTCAAAAGTGGTGAGCTTCTCAAAACCAATTGAAAAAGAAGAGACTGTTGGTATTTTTTCCCCTTTGTCTGTAAAGTTAAATATTGTGATTTCTCCCTATCATTTTGATAATTCCTGGAAAGCATTTCTAGGAGAATTAACTCTTCAGCTTCTTCCTGCACAGAGTTTAATTGAAAATTTTTCCGAAAGGAGTATTACATTGATGAGTTCAGAGTCAAGCAATCAGTTCCTGATTTATGTTCATTCAAAAGGTGAAGATGTAGAGAAACAAAAAAAAGAACCGATGAGTATTTGTGACAAGGGTATTCTGGTGGAGTCATCCTTCAGTGGTGAAATGTTAGAAGATTTGGGGTGGCTACAAAAGAAGAGAAGAATAAAACTCTATCAGAAACCAGAAGGAAATCACATTATCAAGGTTGGAATTTATCTTTTGGAAGCTGGCCTAGCAAAACTAGACTTCTTGAGTGATGCAAATTCAAGAATGAAAAAGTTCAATCAGCTCATGAAGAAAGTAATGGAAAAGTTACACAATTCTATTATTCCAGATGTGTTGGAAGAGGATGAAGATGATCCGGAGAGTGAGCCAGAGGGACAAGACATTGACGAGCTGTATCACTTTGTGAAACAAACACATCAGCAAGAAACGCAGTCCATCCAAGTGGATGTCCAGCATCCTGCATTGATCCCTGTGTTGAGACCCTACCAAAGAGAGGCTGTCAATTGGATGCTACAACAAGAGTGTTTCAGAAGCAGTCCTGCTACTGAAAGTGCCCTGCACTTCTTATGGCGAGAGATTGTTACATCTGAGGGTCTGAAACTCTACTATAATCCATATACAGGCTGCATCATTCGTGAGTACCCAAATTCTGGGCCGCAGTTGCTTGGTGGAATTTTAGCAGATGAGATGGGTCTTGGAAAGACAGTGGAGGTTTTGGCTCTGATTCTGACACATACTCGACAAGATGTCAAGCAAGATGCTCTCACTCTTCCCGAGGGAAAAGTGGTGAATTATTTTATTCCGTCACATTATTTTGGAGGAAAACTGAAAAAGACAGAAATCCAGAATATCGAATTTGAACCAAAAGAAAAAGTTCAATGCCCTCCTACACGTGTGATGATACTGACAGCTGTGAAAGAAATGAATGGAAAAAAAGGAGTGTCCATCCTTTCCATCTATAAGTATGTCAGTTCTATATATAGATACGATGTTCAACGGAACAGGAGTCTTTTGAAACGGATGCTGAAATGTTTAATTTTTGAAGGTCTCGTGAAACAGATCAAAGGCCATGGTTTTTCTGGGACTTTTACATTGGGAAAGAATTACAAGGAAGAGGATATATGTGATAAAACAAAAAAGCAGGCAGTAGGGAGTCCAAGGAAAATTCAGAAAGAAACTAGAAAATCAGGGAACAAGGACACAGATTCTGAATACTTGCCATCAGACACCTCTGATGATGATGATGATCCTTACTATTATTATTATAAGTCCAGGAGAAATCGCAGTAAATTGAGGAAAAAGCTTGTTCCATCCACAAAAAAAGGAAAAAGTCAACCATTTATCAATCCCGATTCACAAGGTCACTGTCCAGCTACTAGCGACTCTGGAATAACTGATGTTGCTATGTCTAAAAGTACATGTATCTCTGAATTCAACCAAGAACATGAAACAGAGGACTGTGCTGAATCTCTAAATCATGCTGATAGTGATGTACCACCTTCTAATACCATGAGTCCCTTTAACACCTCTGATTACCGCTTTGAGTGTATATGTGGTGAACTTGATCAGATAGATCGTAAGCCTCGTGTTCAATGCCTGAAGTGTCACCTGTGGCAACATGCAAAGTGTGTGAATTATGATGAGAAAAATCTGAAGATCAAGCCTTTTTACTGCCCCCACTGCCTTGTTGCAATGGAACCAGTGTCAACAAGAGCAACTCTGATCATCTCTCCAAGTTCCATCTGTCACCAGTGGGTGGATGAGATCAACAGGCATGTGAGGTCGTCATCTCTTCGAGTCTTGGTATATCAAGGAGTGAAGAAAGATGGCTTTTTACAACCTCATTTTTTGGCAGAACAGGATATAGTTATCATTACCTATGATGTACTGCGTTCAGAATTAAATTATGTCGATATCCCACATAGCAATAGTGAGGATGGGCGTCGCCTACGGAACCAGAAGCGCTATATGGCTATCCCGAGCCCCCTGGTAGCTGTGGAGTGGTGGAGGATCTGCCTTGATGAAGCTCAGATGGTTGAGTGTCCCACAGTAAAAGCTGCAGAAATGGCCCAGCGTTTGAGTGGGATTAATCGATGGTGTATCAGTGGCACTCCAGTACAGAGAGGATTAGAGGATCTTTTTGGGTTAGTGGTCTTTCTTGGTATTGAACCTTACTGTGTCAAACACTGGTGGGTTCGACTTCTCTATCGGCCTTACTGCAAGAAGAATCCTCAGCATCTCTACAGCTTTATTGCCAAGATACTGTGGAGGTCTGCAAAGAAAGATGTGATTGACCAAATCCAAATACCACCACAAACCGAAGAAATACACTGGCTCCACTTTTCTCCAGTGGAAAGGCATTTCTATCACCGTCAGCATGAGGTGTGCTGCCAGGATGTGGTGGTAAAACTCAGGAAGATTTCTGACTGGGCTCTGAAGCTCAGCAGCCTAGACAGAAGGACTGTCACCTCTATCCTGTATCCATTGCTGAGGCTCAGACAGGCCTGCTGTCACCCACAGGCTGTTCGTGGAGAGTTCTTGCCACTCCAAAAAAGCACCATGACAATGGAAGAGCTGCTGACATCTTTGCAGAAGAAATGTGGAACTGAATGTGAAGAAGCACATCGACAGCTAGTTTGTGCTCTCAATGGCTTAGCAGGCATTCATATTATTAAAGGTGAGTATGCCTTGGCAGCAGAATTGTACAGAGAAGTGTTGCGCTCCTCGGAGGAACACAAAGGAAAACTCAAAACTGATTCACTTCAAAGACTTCATGCTACCCATAACTTGATGGAATTGTTGATAGCCAGGCACCCAGGGATACCACCTACCTTGCGTGATGGCCGACTTGAGGAAGAGGCCAAACAGCTGCGAGAGCACTACATGAGCAAGTGTAATACAGAAGTTGCTGAAGCCCAGCAAGCTTTATATCCTGTGCAGCAGACCATCCATGAGCTTCAAAGAAAGATTCATTCTAATTCTCCTTGGTGGCTAAATGTGATCCACAGAGCAATAGAATTTACTATTGATGAGGAGCTAGTTCAGCGAGTGCGAAATGAAATAACCAGCAACTACAAGCAACAAACTGGCAAGCTTTCTATGTCAGAGAAGTTCCGTGATTGCAGAGGTCTTCAGTTCTTACTTACAACACAAATGGAAGAGCTAAATAAATGCCAGAAGCTAGTAAGAGAGGCTGTAAAAAACCTGGAGGGACCTCCATCTCGTAATGTTATTGAGTCTGCAACAGTCTGTCACCTCCGACCAGCCAGACTTCCTCTCAACTGCTGTGTCTTTTGTAAAGCTGATGAATTGTTCACAGAGTATGAATCAAAGCTATTTTCCAACACAGTCAAAGGCCAGACTGCAATATTTGAGGAGATGATAGAAGATGAAGAAGGACTGGTGGATGATCGAGCACCTACCACCACCCGGGGTCTCTGGGCAATAAGTGAGACAGAGCGATCTATGAAAGCAATACTATCATTTGCAAAATCACATAGGTTTGATGTTGAATTTGTTGATGAAGGAAGCACTTCAATGGATCTCTTTGAAGCATGGAAGAAGGAATATAAGTTGCTTCATGAATATTGGATGGCTCTGAGGAATCGTGTGTCTGCTGTTGATGAACTTGCAATGGCTACAGAACGACTAAGAGTGCGTGATCCTAGGGAGCCAAAGCCTAATCCGCCTGTTCTTCATATCATTGAACCACATGAGGTAGAACAAAACCGAATAAAACTACTAAATGATAAAGCTTTTGCTACATCACAGCTTCAGAAAAAACTTGGGCAGCTTCTTTACCTAACTAATTTGGAGAAGTCTCAAGATAAAACATCGGGAGGTGTTAATCCAGAACCTTGTCCAATCTGTGCTCGACAGCTAGGAAAACAGTGGGCGGTACTGACCTGTGGTCACTGTTTCTGTAATGAATGCATTTCTATAATTATTGAACAATACAGCGTGGGATCTCACAGAAGCTCCATTAAGTGTGCAATCTGCCGCCAGACCACATCTCACAAAGAAATCTCGTATGTCTTTACCTCAGAGAAAGCAAACCAGGAGGAGGACATCCCTGTGAAGGGCAGCCATTCTACAAAAGTGGAAGCTGTGGTCAGAACTCTGATGAAAATACAGCTTAGAGATCCAGGGGCCAAAGCACTCGTTTTCTCAACGTGGCAAGATGTATTAGATATTATTTCAAAAGCTCTTACTGACAACAACATGGAATTTGCACAAATCAGTCGTGTTAAGACATTTCAGGAGAACCTTTCAGCATTTAAACGTGATCCCCAAATCAATATTTTGCTGCTGCCCCTGCACACAGGTTCTAATGGATTAACTATCATTGAAGCAACTCATGTTCTCTTGGTGGAGCCCATATTGAACCCTGCCCATGAGCTTCAGGCCATAGGGAGGGTGCACCGAATTGGACAGACAAAACCTACTATTGTACACAGATTCTTAATTAAAGCAACAATAGAAGAAAGAATGCAGGCAATGCTGAAAACTGCTGAGAGAAGTCACACGAACTCATCAGCAAAGCATTCAGAGGCCTCTGTCTTGACTGTGGCTGACCTGGCAGACCTATTTACCAAAGAAACTGAAGAGCTTGAATGA
Sequence Length
5052
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
54,339 Da
NCBI Official Full Name
Homo sapiens SNF2 histone linker PHD RING helicase, mRNA
NCBI Official Synonym Full Names
SNF2 histone linker PHD RING helicase
NCBI Official Symbol
SHPRH
NCBI Official Synonym Symbols
bA545I5.2
NCBI Protein Information
E3 ubiquitin-protein ligase SHPRH
UniProt Protein Name
E3 ubiquitin-protein ligase SHPRH
Protein Family
UniProt Gene Name
SHPRH
UniProt Synonym Gene Names
KIAA2023
UniProt Entry Name
SHPRH_HUMAN
NCBI Description
SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases. SHPRH is a functional homolog of S. cerevisiae RAD5 (Unk et al., 2006 [PubMed 17108083]).[supplied by OMIM, Mar 2008]
Uniprot Description
SHPRH: E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'. Belongs to the SNF2/RAD54 helicase family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.6.1.-; EC 3.6.4.-; EC 6.3.2.-; EC 6.3.2.19; Helicase; Ligase; Ubiquitin conjugating system; Ubiquitin ligase
Chromosomal Location of Human Ortholog: 6q24.3
Molecular Function: protein binding; ubiquitin protein ligase binding; ubiquitin-protein ligase activity
Biological Process: protein polyubiquitination; response to DNA damage stimulus
Research Articles on SHPRH
Similar Products
Product Notes
The SHPRH shprh (Catalog #AAA1276437) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGAGCAGCC GACGGAAACG TGCTCCTCCA GTGAGGGTAG ATGAGGAAAA GAGGCAGCAG CTTCATTGGA ATATGCATGA GGACAGAAGG AATGAACCTA TCATCATAAG TGATGATGAC GAGCAGCCCT GCCCAGGTTC AGATACCTCT TCTGCTCATT ATATCATTCT AAGTGATAGT CTAAAGGAAG AAGTGGCTCA CAGAGATAAG AAGAGGTGTT CAAAAGTGGT GAGCTTCTCA AAACCAATTG AAAAAGAAGA GACTGTTGGT ATTTTTTCCC CTTTGTCTGT AAAGTTAAAT ATTGTGATTT CTCCCTATCA TTTTGATAAT TCCTGGAAAG CATTTCTAGG AGAATTAACT CTTCAGCTTC TTCCTGCACA GAGTTTAATT GAAAATTTTT CCGAAAGGAG TATTACATTG ATGAGTTCAG AGTCAAGCAA TCAGTTCCTG ATTTATGTTC ATTCAAAAGG TGAAGATGTA GAGAAACAAA AAAAAGAACC GATGAGTATT TGTGACAAGG GTATTCTGGT GGAGTCATCC TTCAGTGGTG AAATGTTAGA AGATTTGGGG TGGCTACAAA AGAAGAGAAG AATAAAACTC TATCAGAAAC CAGAAGGAAA TCACATTATC AAGGTTGGAA TTTATCTTTT GGAAGCTGGC CTAGCAAAAC TAGACTTCTT GAGTGATGCA AATTCAAGAA TGAAAAAGTT CAATCAGCTC ATGAAGAAAG TAATGGAAAA GTTACACAAT TCTATTATTC CAGATGTGTT GGAAGAGGAT GAAGATGATC CGGAGAGTGA GCCAGAGGGA CAAGACATTG ACGAGCTGTA TCACTTTGTG AAACAAACAC ATCAGCAAGA AACGCAGTCC ATCCAAGTGG ATGTCCAGCA TCCTGCATTG ATCCCTGTGT TGAGACCCTA CCAAAGAGAG GCTGTCAATT GGATGCTACA ACAAGAGTGT TTCAGAAGCA GTCCTGCTAC TGAAAGTGCC CTGCACTTCT TATGGCGAGA GATTGTTACA TCTGAGGGTC TGAAACTCTA CTATAATCCA TATACAGGCT GCATCATTCG TGAGTACCCA AATTCTGGGC CGCAGTTGCT TGGTGGAATT TTAGCAGATG AGATGGGTCT TGGAAAGACA GTGGAGGTTT TGGCTCTGAT TCTGACACAT ACTCGACAAG ATGTCAAGCA AGATGCTCTC ACTCTTCCCG AGGGAAAAGT GGTGAATTAT TTTATTCCGT CACATTATTT TGGAGGAAAA CTGAAAAAGA CAGAAATCCA GAATATCGAA TTTGAACCAA AAGAAAAAGT TCAATGCCCT CCTACACGTG TGATGATACT GACAGCTGTG AAAGAAATGA ATGGAAAAAA AGGAGTGTCC ATCCTTTCCA TCTATAAGTA TGTCAGTTCT ATATATAGAT ACGATGTTCA ACGGAACAGG AGTCTTTTGA AACGGATGCT GAAATGTTTA ATTTTTGAAG GTCTCGTGAA ACAGATCAAA GGCCATGGTT TTTCTGGGAC TTTTACATTG GGAAAGAATT ACAAGGAAGA GGATATATGT GATAAAACAA AAAAGCAGGC AGTAGGGAGT CCAAGGAAAA TTCAGAAAGA AACTAGAAAA TCAGGGAACA AGGACACAGA TTCTGAATAC TTGCCATCAG ACACCTCTGA TGATGATGAT GATCCTTACT ATTATTATTA TAAGTCCAGG AGAAATCGCA GTAAATTGAG GAAAAAGCTT GTTCCATCCA CAAAAAAAGG AAAAAGTCAA CCATTTATCA ATCCCGATTC ACAAGGTCAC TGTCCAGCTA CTAGCGACTC TGGAATAACT GATGTTGCTA TGTCTAAAAG TACATGTATC TCTGAATTCA ACCAAGAACA TGAAACAGAG GACTGTGCTG AATCTCTAAA TCATGCTGAT AGTGATGTAC CACCTTCTAA TACCATGAGT CCCTTTAACA CCTCTGATTA CCGCTTTGAG TGTATATGTG GTGAACTTGA TCAGATAGAT CGTAAGCCTC GTGTTCAATG CCTGAAGTGT CACCTGTGGC AACATGCAAA GTGTGTGAAT TATGATGAGA AAAATCTGAA GATCAAGCCT TTTTACTGCC CCCACTGCCT TGTTGCAATG GAACCAGTGT CAACAAGAGC AACTCTGATC ATCTCTCCAA GTTCCATCTG TCACCAGTGG GTGGATGAGA TCAACAGGCA TGTGAGGTCG TCATCTCTTC GAGTCTTGGT ATATCAAGGA GTGAAGAAAG ATGGCTTTTT ACAACCTCAT TTTTTGGCAG AACAGGATAT AGTTATCATT ACCTATGATG TACTGCGTTC AGAATTAAAT TATGTCGATA TCCCACATAG CAATAGTGAG GATGGGCGTC GCCTACGGAA CCAGAAGCGC TATATGGCTA TCCCGAGCCC CCTGGTAGCT GTGGAGTGGT GGAGGATCTG CCTTGATGAA GCTCAGATGG TTGAGTGTCC CACAGTAAAA GCTGCAGAAA TGGCCCAGCG TTTGAGTGGG ATTAATCGAT GGTGTATCAG TGGCACTCCA GTACAGAGAG GATTAGAGGA TCTTTTTGGG TTAGTGGTCT TTCTTGGTAT TGAACCTTAC TGTGTCAAAC ACTGGTGGGT TCGACTTCTC TATCGGCCTT ACTGCAAGAA GAATCCTCAG CATCTCTACA GCTTTATTGC CAAGATACTG TGGAGGTCTG CAAAGAAAGA TGTGATTGAC CAAATCCAAA TACCACCACA AACCGAAGAA ATACACTGGC TCCACTTTTC TCCAGTGGAA AGGCATTTCT ATCACCGTCA GCATGAGGTG TGCTGCCAGG ATGTGGTGGT AAAACTCAGG AAGATTTCTG ACTGGGCTCT GAAGCTCAGC AGCCTAGACA GAAGGACTGT CACCTCTATC CTGTATCCAT TGCTGAGGCT CAGACAGGCC TGCTGTCACC CACAGGCTGT TCGTGGAGAG TTCTTGCCAC TCCAAAAAAG CACCATGACA ATGGAAGAGC TGCTGACATC TTTGCAGAAG AAATGTGGAA CTGAATGTGA AGAAGCACAT CGACAGCTAG TTTGTGCTCT CAATGGCTTA GCAGGCATTC ATATTATTAA AGGTGAGTAT GCCTTGGCAG CAGAATTGTA CAGAGAAGTG TTGCGCTCCT CGGAGGAACA CAAAGGAAAA CTCAAAACTG ATTCACTTCA AAGACTTCAT GCTACCCATA ACTTGATGGA ATTGTTGATA GCCAGGCACC CAGGGATACC ACCTACCTTG CGTGATGGCC GACTTGAGGA AGAGGCCAAA CAGCTGCGAG AGCACTACAT GAGCAAGTGT AATACAGAAG TTGCTGAAGC CCAGCAAGCT TTATATCCTG TGCAGCAGAC CATCCATGAG CTTCAAAGAA AGATTCATTC TAATTCTCCT TGGTGGCTAA ATGTGATCCA CAGAGCAATA GAATTTACTA TTGATGAGGA GCTAGTTCAG CGAGTGCGAA ATGAAATAAC CAGCAACTAC AAGCAACAAA CTGGCAAGCT TTCTATGTCA GAGAAGTTCC GTGATTGCAG AGGTCTTCAG TTCTTACTTA CAACACAAAT GGAAGAGCTA AATAAATGCC AGAAGCTAGT AAGAGAGGCT GTAAAAAACC TGGAGGGACC TCCATCTCGT AATGTTATTG AGTCTGCAAC AGTCTGTCAC CTCCGACCAG CCAGACTTCC TCTCAACTGC TGTGTCTTTT GTAAAGCTGA TGAATTGTTC ACAGAGTATG AATCAAAGCT ATTTTCCAAC ACAGTCAAAG GCCAGACTGC AATATTTGAG GAGATGATAG AAGATGAAGA AGGACTGGTG GATGATCGAG CACCTACCAC CACCCGGGGT CTCTGGGCAA TAAGTGAGAC AGAGCGATCT ATGAAAGCAA TACTATCATT TGCAAAATCA CATAGGTTTG ATGTTGAATT TGTTGATGAA GGAAGCACTT CAATGGATCT CTTTGAAGCA TGGAAGAAGG AATATAAGTT GCTTCATGAA TATTGGATGG CTCTGAGGAA TCGTGTGTCT GCTGTTGATG AACTTGCAAT GGCTACAGAA CGACTAAGAG TGCGTGATCC TAGGGAGCCA AAGCCTAATC CGCCTGTTCT TCATATCATT GAACCACATG AGGTAGAACA AAACCGAATA AAACTACTAA ATGATAAAGC TTTTGCTACA TCACAGCTTC AGAAAAAACT TGGGCAGCTT CTTTACCTAA CTAATTTGGA GAAGTCTCAA GATAAAACAT CGGGAGGTGT TAATCCAGAA CCTTGTCCAA TCTGTGCTCG ACAGCTAGGA AAACAGTGGG CGGTACTGAC CTGTGGTCAC TGTTTCTGTA ATGAATGCAT TTCTATAATT ATTGAACAAT ACAGCGTGGG ATCTCACAGA AGCTCCATTA AGTGTGCAAT CTGCCGCCAG ACCACATCTC ACAAAGAAAT CTCGTATGTC TTTACCTCAG AGAAAGCAAA CCAGGAGGAG GACATCCCTG TGAAGGGCAG CCATTCTACA AAAGTGGAAG CTGTGGTCAG AACTCTGATG AAAATACAGC TTAGAGATCC AGGGGCCAAA GCACTCGTTT TCTCAACGTG GCAAGATGTA TTAGATATTA TTTCAAAAGC TCTTACTGAC AACAACATGG AATTTGCACA AATCAGTCGT GTTAAGACAT TTCAGGAGAA CCTTTCAGCA TTTAAACGTG ATCCCCAAAT CAATATTTTG CTGCTGCCCC TGCACACAGG TTCTAATGGA TTAACTATCA TTGAAGCAAC TCATGTTCTC TTGGTGGAGC CCATATTGAA CCCTGCCCAT GAGCTTCAGG CCATAGGGAG GGTGCACCGA ATTGGACAGA CAAAACCTAC TATTGTACAC AGATTCTTAA TTAAAGCAAC AATAGAAGAA AGAATGCAGG CAATGCTGAA AACTGCTGAG AGAAGTCACA CGAACTCATC AGCAAAGCAT TCAGAGGCCT CTGTCTTGAC TGTGGCTGAC CTGGCAGACC TATTTACCAA AGAAACTGAA GAGCTTGAAT GA. It is sometimes possible for the material contained within the vial of "SHPRH, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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