SCARA3 cdna clone

SCARA3 cDNA Clone

Cat. Num. AAA1268122

• Gene Names: SCARA3; CSR; APC7; CSR1; MSLR1; MSRL1
• Synonyms: SCARA3; SCARA3 cDNA Clone; SCARA3 cdna clone

• Sequence: atgaaagtgaggtcggccggcggcgatggagatgccttgtgcgttacagaagaggacctggcgggtgacgacgaggacatgccgaccttcccatgcacccagaagggccggccagggccccgctgcagccgctgccagaagaacctatctttgcacacatcggtgcggattctttacctcttcctggccctgctcctggtggccgtggctgtgttggcctctctggttttcagaaaagtggactctctctccgaagacatctccttgacccagtctatttatgacaagaagcttgtgttaatgcagaaaaatctccagggcctggatccgaaagccctgaacaactgctctttctgccatgaagctgggcagctggggccagagatccgaaaactgcaggaggagctggagggaattcagaagctgcttctggcccaggaggtgcagctggaccagaccttacaggcccaggaggtgctctccaccaccagcagacaaatctcccaggagatgggcagttgctccttctccatccaccaggttaaccagtctctggggctcttcctggcccaggtgagaggctggcaggccaccacagctggcctggacctctctctgaaggacctcacccaggagtgctacgatgtcaaggctgcagtgcaccagatcaacttcaccgtggggcagacttccgagtggatccacgggatccagcggaagacagacgaggagaccctgaccctccagaagattgtcaccgactggcagaactacacacggctcttcagcggcctgcgcaccacctccaccaagactggagaggcggtcaagaacatccaggccaccctgggggcctcctcacagcgcatcagccagaactcagagagcatgcacgacctggtactccaggtcatgggcttgcagctgcagctggataacatctcgtccttcctggatgaccacgaagagaacatgcatgatcttcagtaccatacccactacgcccagaaccgcactgtggagaggtttgagtctctggaaggacgcatggcttctcacgagattgaaattggcaccatcttcaccaacatcaatgccaccgacaaccacgtgcacagcatgctcaagtacctggatgacgtgcggctctcctgcacgctgggcttccacacccatgccgaggagctctactacctgaacaagtctgtctccatcatgctgggcaccacagacctgctccgggagcgcttcagcctgctcagtgcccggctggacctcaacgtccggaacctctccatgatcgtggaggagatgaaggcagtggacacacagcatggagaaatccttcgcaatgtcaccatcctacgaggtcacactttgttttcacataatcggatatga
• Sequence Length: 1401

• Vector: pENTR223.1 or pUC
• Clone Sequence Report: Provided with product shipment

NCBI and Uniprot Product Information

• NCBI GI #: 38173793
• NCBI GeneID: 51435
• Molecular Weight: 52,434 Da
• NCBI Official Full Name: Homo sapiens scavenger receptor class A, member 3, mRNA
• NCBI Official Synonym Full Names: scavenger receptor class A member 3
• NCBI Official Symbol: SCARA3
• NCBI Official Synonym Symbols: CSR; APC7; CSR1; MSLR1; MSRL1
• NCBI Protein Information: scavenger receptor class A member 3
• UniProt Protein Name: Scavenger receptor class A member 3
• Protein Family: Scavenger receptor
• UniProt Gene Name: SCARA3
• UniProt Synonym Gene Names: CSR
• UniProt Entry Name: SCAR3_HUMAN

NCBI Description

This gene encodes a macrophage scavenger receptor-like protein. This protein has been shown to deplete reactive oxygen species, and thus play an important role in protecting cells from oxidative stress. The expression of this gene is induced by oxidative stress. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

CSR: a ubiquitous single-pass type II membrane protein of the endoplasmic reticulum and/or Golgi that may function as a tumor suppressor. Protects against intracellular damage by scavenging oxidative molecules produced by oxidative stress and UV irradiation. Frequently down-regulated and methylated in prostate cancer samples. Two alternatively spliced human isoforms have been described, CSR1 and -2.

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 8p21

Molecular Function: protein binding; scavenger receptor activity; structural molecule activity

Biological Process: response to oxidative stress; toll-like receptor 3 signaling pathway; UV protection