SBF2 cdna clone
SBF2 cDNA Clone
Gene Names
SBF2; CMT4B2; MTMR13; DENND7B
Synonyms
SBF2; SBF2 cDNA Clone; SBF2 cdna clone
Sequence
atggcccggctggctgactacttcattgtggtaggctatgaccacgagaagccaggatcaggagaaggtctggggaaaataatccagagatttccacagaaggactgggatgatacaccttttccacagggaattgagttgttttgtcagcctggcgggtggcagctgtccagagagaggaagcagccaacgttctttgtggttgtcctgacagacattgactcagatcgacattactgctcatgcctaaccttctatgaggcagagatcaatcttcagggaacaaagaaggaagagattgaaggtgaagcaaaagtgtctggtttaattcagcctgcagaagtgtttgctcccaaaagcctggtgttggtatccagattatattatccagaaatttttagggcttgcctgggtttgatctataccgtgtatgtggacagcctgaatgtctccttggaaagtctaattgcaaacctttgtgcctgccttgtcccagcggctggagggtctcagaagctgttttctttgggtgcaggagatagacagttgatccagactcctttacatgatagtcttcctatcacgggcactagtgtggctctcctgttccagcaattgggaattcaaaatgtcctcagcctcttttgtgcagtcctcacagaaaataaggttctcttccattctgcaagtttccagagacttagtgatgcttgtagagccctggaatctttaatgtttcctcttaaatatagttatccttatatccctattctcccggctcagctactggaagttctaagttccccaacgcctttcattattggagtacattctgtctttaaaactgatgtccatgaacttttagatgtaatcatagcagatttggatggaggcactattaaaattcccgaatgtattcacctctcttccctcccagaaccacttctacatcagactcaatcagctctttctttgattttacacccagatttggaagtagcagatcatgcttttcctcctccacgaacagctttatcccactcaaaaatgctggataaagaggtgcgagccgttttccttagattatttgcacaactcttccaaggatatagatcctgcctgcaacttataagaattcatgcagagccagtaatacatttccacaagacagcattcttggggcagcgtggtttggtcgagaatgatttcctcactaaagtactcagtggaatggcatttgcaggttttgtttcagaaagaggtcctccttatagatcttgtgatctctttgatgagttggtagcctttgaagtagagagaattaaagttgaagaaaataacccagtgaagatgataaagcatgtcagggaacttgctgagcaactattcaaaaatgagaatccaaatcctcatatggcattccagaaagttccacggccaacagaaggatcccatttgcgagttcatattcttcctttcccagagattaatgaagcccgggttcaggaattaatacaggaaaatgttgctaagaaccagaatgcacctcctgccacacgaatagaaaagaaatgtgttgtgccagcaggtccacctgttgtttcgataatggacaaggtgacgacagttttcaacagtgcacaaagactagaagttgtcagaaactgtatctcattcatatttgaaaataaaattttggaaactgaaaagacccttcctgctgcactcagagcccttaaaggaaaggcagcaagacagtgtctcactgatgaattgggtttgcatgtccagcaaaaccgggcaatattagaccatcaacagtttgactacataataaggatgatgaattgtactctacaggattgttcaagtttagaagaatacaacattgccgcagcattactccctttgaccagtgctttctataggaaacttgcccctggagtcagccagtttgcttacacgtgtgtacaagaccaccccatttggacaaatcagcaattttgggagacaaccttttacaatgcagtgcaggaacaggttcgctccctttatctctcagccaaggaagacaatcatgccccgcatctgaagcaaaaggataagcttcctgatgaccattatcaggagaagacagcaatggacctggcagctgagcaactacgcctttggcctaccctgagcaagtcaactcagcaagagctagtgcaacatgaggaaagcactgtctttagtcaggccattcactttgcaaacctcatggtgaacctgctagttccactcgacacaagtaaaaacaagctcctaagaacatcagcgccaggtgactgggagagcggaagcaacagcattgtcacaaacagtattgcaggaagtgtagctgagagctatgatacagagagtgggtttgaagattcagagaatactgacattgccaattctgttgtgcggttcattacccgatttattgacaaagtttgtacagagagtggagttactcaggatcacatcaagagccttcattgcatgataccaggaattgtagctatgcacattgagaccctagaagcagtacatcgagaaagcagaagacttccgcctattcagaagcccaagattcttagacctgctctgctgccaggagaagaaattgtctgtgagggtcttcgagtcttgctggatcctgatggaagagaagaagctactggaggtcttcttggaggccctcagctcctgccagcagaaggagccttgttcctcaccacatacagaattctcttcagaggaacaccccatgatcagttagtgggtgagcagacagttgtgcggagctttcccattgcctccatcaccaaggagaagaagattacaatgcagaaccagctacagcagaacatgcaagaaggactgcagatcacatcagcatcttttcagttgattaaggtagcatttgatgaagaagtcagtccagaagtagtagagatctttaagaaacagctgatgaagttccgttatcctcagtccattttcagtacctttgcttttgctgctggacaaactaccccacaaataattttaccaaaacagaaggaaaagaacacttcttttcgtaccttctcaaaaacaattgtgaaaggtgccaaaagggcagggaaaatgacaattgggcggcaatatttactgaagaagaagacagggacaattgtggaagaaagagtaaatcgtcctggatggaatgaagatgatgatgtatctgtttcagatgagagtgagctccccacaagtaccaccctgaaggcctccgagaagtctacaatggaacagttggtggaaaaagcttgtttcagagactatcagcgtttaggtttaggaaccataagtggcagctcttcccgttcaagacccgagtattttagaattactgcctccaacaggatgtattcactctgccggagctatcctggccttttagtcgtacctcaagctgtacaggacagtagtttaccaagagtagctcgctgctatcgacacaatcgcctgcctgttgtatgttggaagaactcaagaagtggtactctgctcctccgatctggaggattccatgggaagggagtcgttggtcttttcaaatctcagaactcccctgaggccgctcctacctcctctttagaatcttccagtagcatagaacaagagaaatacttgcaagccttactgaatgctgtttctgtccatcagaaactcagaggcaacagcactcttactgtcaggccagcctttgctctatctccaggtgtgtgggcaagtcttcgctctagcactcgcttgatcagctctccaacatccttcattgatgttggcgcccggctggcaggcaaggatcactcggcctccttcagtaacagcagctacctacaaaaccagctcttgaaacggcaagcagccctttacatatttggtgaaaagtcgcaactaaggaacttcaaggtagaatttgctttaaattgtgagtttgttcctgttgaatttcatgaaatccggcaagtgaaagccagttttaagaagctgatgagggcttgtatcccaagcaccatccctactgactcagaagtgaccttcctgaaagcgctgggagattctgagtggttcccacagcttcacaggataatgcagctggctgtggttgtatcagaagtacttgagaatggttcctcagttttggtctgtttggaggaaggctgggacatcactgcacaagtgacatccctggttcagttactcagtgatcccttttataggacacttgaaggcttccagatgttggttgaaaaagagtggctctcttttggtcacaaattcagtcagaggagcagcttgaccctcaactgtcaggggagtggttttgctccagtcttcttacagttcttagactgtgtacaccaggttcacaaccagtatccaactgagtttgaattcaatctctattacttaaagttcttggctttccactatgtgtctaatcgctttaaaacatttctcctggattcagactatgaaagattagagcacggaactttatttgatgataaaggagaaaagcatgccaaaaaaggagtctgtatttgggaatgtattgacagaatgcacaagaggagtcccattttctttaattatttatattcaccattggaaatagaggctctaaagcccaatgtaaacgtctctagcctcaagaagtgggattactacatagaagagaccctgtccacaggcccttcctatgactggatgatgctaacccccaagcacttcccctccgaagactctgacctggctggagaagctgggccacggagccagaggagaacagtgtggccatgctatgatgatgtcagctgtactcagcctgatgctctcaccagccttttcagtgaaattgaaaaattggagcacaaattgaaccaagcccctgagaagtggcagcagctgtgggaaagggtaaccgtggaccttaaagaagaaccaagaacagatcgctcccaaagacacctgtcgagatccccaggaattgtgtctaccaacctaccttcctatcagaagaggtctctgctacatctcccagacagcagcatgggggaggaacagaattccagcatctccccatccaatggagtggagcgaagagcagccacgctctatagccagtatacatccaagaatgatgaaaacaggtcctttgagggaacactttataaaagaggggctttgctgaaaggttggaagccccgttggtttgttttggatgtaacaaaacatcagctgcgctactatgactcaggtgaggacacaagctgtaaaggccacattgatctggctgaagtagaaatggtcatccctgctggccccagcatgggagccccaaagcacacaagtgacaaggctttctttgatctcaagaccagcaaacgtgtgtataacttctgcgcccaggatggacagagtgcccagcaatggatggacaagatccagagttgtatctctgatgcctga
Sequence Length
5550
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
129,344 Da
NCBI Official Full Name
Homo sapiens SET binding factor 2, mRNA
NCBI Official Synonym Full Names
SET binding factor 2
NCBI Official Symbol
SBF2
NCBI Official Synonym Symbols
CMT4B2; MTMR13; DENND7B
NCBI Protein Information
myotubularin-related protein 13
UniProt Protein Name
Myotubularin-related protein 13
Protein Family
UniProt Gene Name
SBF2
UniProt Synonym Gene Names
CMT4B2; KIAA1766; MTMR13
UniProt Entry Name
MTMRD_HUMAN
NCBI Description
This gene encodes a pseudophosphatase and member of the myotubularin-related protein family. This gene maps within the CMT4B2 candidate region of chromosome 11p15 and mutations in this gene have been associated with Charcot-Marie-Tooth Disease, type 4B2. [provided by RefSeq, Jul 2008]
Uniprot Description
MTMR13: a widely expressed pseudophosphatase and peripheral membrane guanine nucleotide exchange factor (GEF) that activates RAB28, a small G protein of the Rab subfamily. Promotes Rab21 GTPase activation associated with PI(3)P endosomes. Coordinates PIP3 and Rab21 regulation in an endosomal pathway. Functions together with Mtm and Rab21, along with Rab11-mediated endosomal trafficking, to control macrophage protrusion formation and to promote turnover of a PI(3)P subpool essential for endosomal trafficking. Interacts with MTMR2. Defects in MTMR13 are the cause of Charcot-Marie-Tooth disease type 4B2 (CMT4B2). CMT4B2 is a recessive form of Charcot-Marie-Tooth disease, the most common inherited disorder of the peripheral nervous system. Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. Two isoforms of the human protein are produced by alternative splicing.
Protein type: GEFs; GEFs, Rab
Chromosomal Location of Human Ortholog: 11p15.4
Cellular Component: membrane
Molecular Function: protein binding; Rab guanyl-nucleotide exchange factor activity
Disease: Charcot-marie-tooth Disease, Type 4b2
Research Articles on SBF2
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Product Notes
The SBF2 sbf2 (Catalog #AAA1275014) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggcccggc tggctgacta cttcattgtg gtaggctatg accacgagaa gccaggatca ggagaaggtc tggggaaaat aatccagaga tttccacaga aggactggga tgatacacct tttccacagg gaattgagtt gttttgtcag cctggcgggt ggcagctgtc cagagagagg aagcagccaa cgttctttgt ggttgtcctg acagacattg actcagatcg acattactgc tcatgcctaa ccttctatga ggcagagatc aatcttcagg gaacaaagaa ggaagagatt gaaggtgaag caaaagtgtc tggtttaatt cagcctgcag aagtgtttgc tcccaaaagc ctggtgttgg tatccagatt atattatcca gaaattttta gggcttgcct gggtttgatc tataccgtgt atgtggacag cctgaatgtc tccttggaaa gtctaattgc aaacctttgt gcctgccttg tcccagcggc tggagggtct cagaagctgt tttctttggg tgcaggagat agacagttga tccagactcc tttacatgat agtcttccta tcacgggcac tagtgtggct ctcctgttcc agcaattggg aattcaaaat gtcctcagcc tcttttgtgc agtcctcaca gaaaataagg ttctcttcca ttctgcaagt ttccagagac ttagtgatgc ttgtagagcc ctggaatctt taatgtttcc tcttaaatat agttatcctt atatccctat tctcccggct cagctactgg aagttctaag ttccccaacg cctttcatta ttggagtaca ttctgtcttt aaaactgatg tccatgaact tttagatgta atcatagcag atttggatgg aggcactatt aaaattcccg aatgtattca cctctcttcc ctcccagaac cacttctaca tcagactcaa tcagctcttt ctttgatttt acacccagat ttggaagtag cagatcatgc ttttcctcct ccacgaacag ctttatccca ctcaaaaatg ctggataaag aggtgcgagc cgttttcctt agattatttg cacaactctt ccaaggatat agatcctgcc tgcaacttat aagaattcat gcagagccag taatacattt ccacaagaca gcattcttgg ggcagcgtgg tttggtcgag aatgatttcc tcactaaagt actcagtgga atggcatttg caggttttgt ttcagaaaga ggtcctcctt atagatcttg tgatctcttt gatgagttgg tagcctttga agtagagaga attaaagttg aagaaaataa cccagtgaag atgataaagc atgtcaggga acttgctgag caactattca aaaatgagaa tccaaatcct catatggcat tccagaaagt tccacggcca acagaaggat cccatttgcg agttcatatt cttcctttcc cagagattaa tgaagcccgg gttcaggaat taatacagga aaatgttgct aagaaccaga atgcacctcc tgccacacga atagaaaaga aatgtgttgt gccagcaggt ccacctgttg tttcgataat ggacaaggtg acgacagttt tcaacagtgc acaaagacta gaagttgtca gaaactgtat ctcattcata tttgaaaata aaattttgga aactgaaaag acccttcctg ctgcactcag agcccttaaa ggaaaggcag caagacagtg tctcactgat gaattgggtt tgcatgtcca gcaaaaccgg gcaatattag accatcaaca gtttgactac ataataagga tgatgaattg tactctacag gattgttcaa gtttagaaga atacaacatt gccgcagcat tactcccttt gaccagtgct ttctatagga aacttgcccc tggagtcagc cagtttgctt acacgtgtgt acaagaccac cccatttgga caaatcagca attttgggag acaacctttt acaatgcagt gcaggaacag gttcgctccc tttatctctc agccaaggaa gacaatcatg ccccgcatct gaagcaaaag gataagcttc ctgatgacca ttatcaggag aagacagcaa tggacctggc agctgagcaa ctacgccttt ggcctaccct gagcaagtca actcagcaag agctagtgca acatgaggaa agcactgtct ttagtcaggc cattcacttt gcaaacctca tggtgaacct gctagttcca ctcgacacaa gtaaaaacaa gctcctaaga acatcagcgc caggtgactg ggagagcgga agcaacagca ttgtcacaaa cagtattgca ggaagtgtag ctgagagcta tgatacagag agtgggtttg aagattcaga gaatactgac attgccaatt ctgttgtgcg gttcattacc cgatttattg acaaagtttg tacagagagt ggagttactc aggatcacat caagagcctt cattgcatga taccaggaat tgtagctatg cacattgaga ccctagaagc agtacatcga gaaagcagaa gacttccgcc tattcagaag cccaagattc ttagacctgc tctgctgcca ggagaagaaa ttgtctgtga gggtcttcga gtcttgctgg atcctgatgg aagagaagaa gctactggag gtcttcttgg aggccctcag ctcctgccag cagaaggagc cttgttcctc accacataca gaattctctt cagaggaaca ccccatgatc agttagtggg tgagcagaca gttgtgcgga gctttcccat tgcctccatc accaaggaga agaagattac aatgcagaac cagctacagc agaacatgca agaaggactg cagatcacat cagcatcttt tcagttgatt aaggtagcat ttgatgaaga agtcagtcca gaagtagtag agatctttaa gaaacagctg atgaagttcc gttatcctca gtccattttc agtacctttg cttttgctgc tggacaaact accccacaaa taattttacc aaaacagaag gaaaagaaca cttcttttcg taccttctca aaaacaattg tgaaaggtgc caaaagggca gggaaaatga caattgggcg gcaatattta ctgaagaaga agacagggac aattgtggaa gaaagagtaa atcgtcctgg atggaatgaa gatgatgatg tatctgtttc agatgagagt gagctcccca caagtaccac cctgaaggcc tccgagaagt ctacaatgga acagttggtg gaaaaagctt gtttcagaga ctatcagcgt ttaggtttag gaaccataag tggcagctct tcccgttcaa gacccgagta ttttagaatt actgcctcca acaggatgta ttcactctgc cggagctatc ctggcctttt agtcgtacct caagctgtac aggacagtag tttaccaaga gtagctcgct gctatcgaca caatcgcctg cctgttgtat gttggaagaa ctcaagaagt ggtactctgc tcctccgatc tggaggattc catgggaagg gagtcgttgg tcttttcaaa tctcagaact cccctgaggc cgctcctacc tcctctttag aatcttccag tagcatagaa caagagaaat acttgcaagc cttactgaat gctgtttctg tccatcagaa actcagaggc aacagcactc ttactgtcag gccagccttt gctctatctc caggtgtgtg ggcaagtctt cgctctagca ctcgcttgat cagctctcca acatccttca ttgatgttgg cgcccggctg gcaggcaagg atcactcggc ctccttcagt aacagcagct acctacaaaa ccagctcttg aaacggcaag cagcccttta catatttggt gaaaagtcgc aactaaggaa cttcaaggta gaatttgctt taaattgtga gtttgttcct gttgaatttc atgaaatccg gcaagtgaaa gccagtttta agaagctgat gagggcttgt atcccaagca ccatccctac tgactcagaa gtgaccttcc tgaaagcgct gggagattct gagtggttcc cacagcttca caggataatg cagctggctg tggttgtatc agaagtactt gagaatggtt cctcagtttt ggtctgtttg gaggaaggct gggacatcac tgcacaagtg acatccctgg ttcagttact cagtgatccc ttttatagga cacttgaagg cttccagatg ttggttgaaa aagagtggct ctcttttggt cacaaattca gtcagaggag cagcttgacc ctcaactgtc aggggagtgg ttttgctcca gtcttcttac agttcttaga ctgtgtacac caggttcaca accagtatcc aactgagttt gaattcaatc tctattactt aaagttcttg gctttccact atgtgtctaa tcgctttaaa acatttctcc tggattcaga ctatgaaaga ttagagcacg gaactttatt tgatgataaa ggagaaaagc atgccaaaaa aggagtctgt atttgggaat gtattgacag aatgcacaag aggagtccca ttttctttaa ttatttatat tcaccattgg aaatagaggc tctaaagccc aatgtaaacg tctctagcct caagaagtgg gattactaca tagaagagac cctgtccaca ggcccttcct atgactggat gatgctaacc cccaagcact tcccctccga agactctgac ctggctggag aagctgggcc acggagccag aggagaacag tgtggccatg ctatgatgat gtcagctgta ctcagcctga tgctctcacc agccttttca gtgaaattga aaaattggag cacaaattga accaagcccc tgagaagtgg cagcagctgt gggaaagggt aaccgtggac cttaaagaag aaccaagaac agatcgctcc caaagacacc tgtcgagatc cccaggaatt gtgtctacca acctaccttc ctatcagaag aggtctctgc tacatctccc agacagcagc atgggggagg aacagaattc cagcatctcc ccatccaatg gagtggagcg aagagcagcc acgctctata gccagtatac atccaagaat gatgaaaaca ggtcctttga gggaacactt tataaaagag gggctttgct gaaaggttgg aagccccgtt ggtttgtttt ggatgtaaca aaacatcagc tgcgctacta tgactcaggt gaggacacaa gctgtaaagg ccacattgat ctggctgaag tagaaatggt catccctgct ggccccagca tgggagcccc aaagcacaca agtgacaagg ctttctttga tctcaagacc agcaaacgtg tgtataactt ctgcgcccag gatggacaga gtgcccagca atggatggac aagatccaga gttgtatctc tgatgcctga. It is sometimes possible for the material contained within the vial of "SBF2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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