RNF181 cdna clone
RNF181 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
RNF181 binds the integrin alpha-IIb (ITGA2B; MIM 607759)/beta-3 (ITGB3; MIM 173470) complex and has E3 ubiquitin ligase activity (Brophy et al., 2008 [PubMed 18331836]).[supplied by OMIM, Dec 2008]
Uniprot Description
RNF181: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Belongs to the RNF181 family.
Protein type: Ubiquitin ligase; Ubiquitin conjugating system; Ligase; EC 6.3.2.-
Chromosomal Location of Human Ortholog: 2p11.2
Molecular Function: ubiquitin-protein ligase activity
Biological Process: proteasomal ubiquitin-dependent protein catabolic process; protein autoubiquitination; protein polyubiquitination; protein ubiquitination during ubiquitin-dependent protein catabolic process
Research Articles on RNF181
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Product Notes
The RNF181 rnf181 (Catalog #AAA1270103) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggcgtcct atttcgatga acacgactgc gagccgtcgg accctgagca ggagacgcga accaacatgc tgctggagct cgcaaggtca cttttcaata ggatggactt tgaagacttg gggttggtag tagattggga ccaccacctg cctccaccag ctgccaagac tgtggttgag aacctcccca ggacagtcat cagaggctct caggctgagc tcaagtgccc cgtgtgtctt ttggaatttg aggaggagga gactgccatt gagatgcctt gccatcacct tttccattcc agctgcattc tgccctggct aagcaagaca aattcctgtc ccttgtgccg ctatgagctg cccactgatg acgacactta tgaggagcac agacgagata aggctcgaaa acagcagcag caacaccgac tggagaacct ccatggagcc atgtacacgt ga. It is sometimes possible for the material contained within the vial of "RNF181, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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