RHBDL1 cdna clone
RHBDL1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein similar to Rhomboid in Drosophila which is involved in signalling in the Spitz/epidermal growth factor receptor/mitogen-activated protein kinase pathway. The Rhomboid family of proteins consists of intramembrane serine proteases containing several transmembrane domains. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Uniprot Description
RHBDL1: May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Belongs to the peptidase S54 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.21.105; Membrane protein, multi-pass; Protease; Membrane protein, integral
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: integral to plasma membrane; membrane; mitochondrial inner membrane
Molecular Function: serine-type endopeptidase activity
Biological Process: protein processing; signal transduction
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Product Notes
The RHBDL1 rhbdl1 (Catalog #AAA1270948) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGGTAGGG TGGAAGACGG GGGAACAACT GAGGAGCTGG AGGACTGGGA CCCAGGCACC AGTGCCCTGC CAGCTCCTGG GATCAAGCAG GGTCCCAGGG AACAGACAGG CACGGGGCCC CTGTCCCAAA AGTGCTGGGA GCCTGAGCCT GATGCTCCCA GCCAGCCTGG CCCAGCCCTT TGGTCCAGGG GTCGGGCCCG CACTCAGGCC TTGGCTGGCG GCTCCTCACT GCAGCAGCTG GACCCCGAGA ACACAGGCTT CATCGGTGCG GACACCTTCA CTGGCCTGGT GCACAGCCAT GAGCTGCCCC TGGACCCGGC CAAGCTGGAC ATGCTGGTGG CCCTGGCTCA GAGCAACGAG CAGGGCCAGG TCTGCTACCA GGAGCTGGTG GACCTGATCA GCAGCAAGCG CTCCAGCAGT TTCAAGCGGG CCATTGCTAA CGGACAGCGG GCACTGCCCC GGGACGGGCC GCTGGATGAG CCAGGCCTAG GTGTCTACAA GCGGTTTGTG CGTTACGTGG CCTACGAGAT CCTGCCTTGT GAGGTGGACC GCCGCTGGTA CTTCTACCGT CACCGCAGCT GCCCACCCCC CGTGTTCATG GCCTCGGTCA CTCTTGCCCA GATCATCGTG TTCCTGTGTT ACGGGGCCCG CCTCAACAAG TGGGTGCTGC AGACCTACCA CCCCGAGTAC ATGAAGAGCC CCCTTGTGTA CCACCCCGGG CACCGTGCCC GCGCCTGGCG CTTCCTCACC TACATGTTCA TGCACGTTGG GCTGGAGCAG CTGGGGTTCA ACGCCCTCCT GCAGCTGATG ATCGGGGTGC CCCTGGAGAT GGTGCACGGC CTGCTCCGCA TCAGCCTGCT CTACCTGGCA GGCGTGCTGG CAGGCTCCCT AACCGTCTCC ATCACCGACA TGCGGGCCCC GGTGGTGGGA GGCTCCGGCG GGGTCTACGC CCTGTGCTCG GCACACCTGG CCAACGTTGT CATGAACTGG GCTGGGATGA GATGTCCCTA CAAGTTGCTG AGGATGGTGC TGGCCTTGGT GTGCATGAGC TCCGAGGTGG GCCGGGCCGT GTGGCTGCGC TTCTCCCCGC CGCTGCCCGC CTCGGGCCCA CAGCCCAGCT TCATGGCGCA CCTGGCAGGC GCGGTGGTGG GGGTGAGCAT GGGCCTGACC ATCCTGCGGA GCTACGAGGA GCGCCTGCGG GACCAGTGCG GCTGGTGGGT GGTGCTGCTG GCCTACGGCA CCTTCCTGCT CTTCGCCGTC TTCTGGAACG TCTTCGCCTA CGACCTGCTG GGCGCCCACA TCCCCCCACC GCCCTGA. It is sometimes possible for the material contained within the vial of "RHBDL1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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